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ChemicalBook >> CAS DataBase List >> (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

$32 - $21666
Product name: (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride
CAS: 149690-12-0
MF: C20H26ClNO2
MW: 347.88
EINECS:695-675-7
MDL Number:MFCD27955983
Synonyms:(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate HCl;LCZ696 Intermediate2;[1,1'-Biphenyl]-4-pentanoic acid, γ-amino-α-methyl-, ethyl ester, hydrochloride (1:1), (αR,γS)-;(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate;(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride;(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride (1:1);(2R, 4S) - ethyl 5- ([1,1'- biphenyl]-4- group) -4- amino -2- methyl valerate hydrochloride;acubitril Impurity 9 HCl

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aablocks
AccelPharmtech
ACHEMBLOCK
AK Scientific
Alichem
Ambeed
Biosynth
Chemenu
Crysdot
Labseeker
Synthonix
TRC

Package

50mg
1g
5g
10g
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50g
100g
1000g
1kg

Manufactureraablocks
Product numberAA00ANBT
Product description(2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 98%
Packaging1g
Price$32
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00ANBT
Product description(2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 98%
Packaging5g
Price$140
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00ANBT
Product description(2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 98%
Packaging10g
Price$228
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00ANBT
Product description(2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 98%
Packaging25g
Price$439
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00ANBT
Product description(2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 98%
Packaging100g
Price$1280
Updated2026-05-28
Buy

ManufacturerAccelPharmtech
Product numberXP1500
Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%
Packaging25G
Price$710
Updated2021-12-16
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ManufacturerAccelPharmtech
Product numberXP1500
Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride 99%
Packaging25G
Price$710
Updated2026-05-21
Buy

ManufacturerAccelPharmtech
Product numberXP1500
Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%
Packaging5G
Price$280
Updated2021-12-16
Buy

ManufacturerAccelPharmtech
Product numberXP1500
Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride 99%
Packaging5G
Price$280
Updated2026-05-21
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ManufacturerAccelPharmtech
Product numberXP1500
Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride 99%
Packaging1G
Price$230
Updated2026-05-21
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ManufacturerAccelPharmtech
Product numberXP1500
Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%
Packaging1G
Price$230
Updated2021-12-16
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ManufacturerACHEMBLOCK
Product numberX182054
Product descriptionethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 95%
Packaging25G
Price$495
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberX182054
Product descriptionethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 95%
Packaging5G
Price$140
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number2498DC
Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride
Packaging25g
Price$870
Updated2021-12-16
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ManufacturerAlichem
Product number149690120
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride
Packaging25g
Price$490
Updated2021-12-16
Buy

ManufacturerAlichem
Product number149690120
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride
Packaging10g
Price$250
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00ANBT	(2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 98%	1g	$32	2026-05-28	Buy
aablocks	AA00ANBT	(2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 98%	5g	$140	2026-05-28	Buy
aablocks	AA00ANBT	(2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 98%	10g	$228	2026-05-28	Buy
aablocks	AA00ANBT	(2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 98%	25g	$439	2026-05-28	Buy
aablocks	AA00ANBT	(2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 98%	100g	$1280	2026-05-28	Buy
AccelPharmtech	XP1500	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%	25G	$710	2021-12-16	Buy
AccelPharmtech	XP1500	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride 99%	25G	$710	2026-05-21	Buy
AccelPharmtech	XP1500	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%	5G	$280	2021-12-16	Buy
AccelPharmtech	XP1500	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride 99%	5G	$280	2026-05-21	Buy
AccelPharmtech	XP1500	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride 99%	1G	$230	2026-05-21	Buy
AccelPharmtech	XP1500	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%	1G	$230	2021-12-16	Buy
ACHEMBLOCK	X182054	ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 95%	25G	$495	2026-05-27	Buy
ACHEMBLOCK	X182054	ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 95%	5G	$140	2026-05-27	Buy
AK Scientific	2498DC	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride	25g	$870	2021-12-16	Buy
Alichem	149690120	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride	25g	$490	2021-12-16	Buy
Alichem	149690120	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride	10g	$250	2021-12-16	Buy

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Properties

Melting point :155 - 162°C
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
Stability :Hygroscopic
InChI :InChI=1/C20H25NO2.ClH/c1-3-23-20(22)15(2)13-19(21)14-16-9-11-18(12-10-16)17-7-5-4-6-8-17;/h4-12,15,19H,3,13-14,21H2,1-2H3;1H/t15-,19+;/s3
InChIKey :MYJTZLYRAWUSLB-MTPCZXHRNA-N
SMILES :C(C1C=CC(C2C=CC=CC=2)=CC=1)[C@@H](N)C[C@@H](C)C(=O)OCC.Cl |&1:13,16,r|

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is used as a reagent in the synthesis of LCZ696, an angiotensin II receptor and neprilysin receptor dual inhibitor. (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is also used as a reagent in the preparation of novel NEP inhibitor prodrugs for the treatment of hypertension and cardiovascular diseases.

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Suppliers and manufacturers

career henan chemical co

$100.00
(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate CAS:149690-12-0

Capot Chemical Co.,Ltd.

Beijing Cooperate Pharmaceutical Co.,Ltd

Henan Tianfu Chemical Co.,Ltd.

ATK CHEMICAL COMPANY LIMITED

Jinan Finer Chemical Co., Ltd

HubeiwidelychemicaltechnologyCo.,Ltd

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(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

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