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ChemicalBook >> CAS DataBase List >> (S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid

(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid

(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid price.
  • $19 - $1780
  • Product name: (S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid
  • CAS: 17257-71-5
  • MF: C10H9F3O3
  • MW: 234.17
  • EINECS:241-292-1
  • MDL Number:MFCD00064200
  • Synonyms:(-)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETIC ACID;(-)-A-METHOXY-A-TRIFLUOROMETHYLPHENYLACETIC ACID;(S)-(-)-MOSHER'S ACID;(S)-(-)-MPTA;(S)-(-)-A-METHOXY-A-(TRIFLUOROMETHYL)PHENYLACETIC ACID;(S)-(-)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETIC ACID;(S)-(-)-2-METHOXY-2-(TRIFLUOROMETHYL)PHENYLACETIC ACID;(S)-(-)-1-METHOXY-1-(TRIFLUOROMETHYL)PHENYLACETIC ACID
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  • ManufacturerA2B
  • Product numberAI39068
  • Product description(S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic Acid 98%
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  • Price$231
  • Updated2026-05-25
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  • Updated2026-05-25
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  • ManufacturerA2B
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  • Price$25
  • Updated2026-05-25
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  • ManufacturerA2B
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  • Price$19
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA00HZI8
  • Product description(S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic Acid 97%
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  • Price$261
  • Updated2026-05-29
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  • Manufactureraablocks
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  • Manufactureraablocks
  • Product numberAA00HZI8
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  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00HZI8
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  • Price$72
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  • ManufacturerACHEMBLOCK
  • Product numberW167585
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  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberW167585
  • Product description(S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid 97%
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  • Price$120
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberW167585
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  • Updated2026-05-27
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  • ManufacturerAHH
  • Product numberMT-17275
  • Product description(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid 97%
  • Packaging5g
  • Price$508
  • Updated2026-05-26
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Manufacturer Product number Product description Packaging Price Updated Buy
A2B AI39068 (S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic Acid 98% 5g $231 2026-05-25 Buy
A2B AI39068 (S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic Acid 98% 1g $63 2026-05-25 Buy
A2B AI39068 (S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic Acid 98% 500mg $49 2026-05-25 Buy
A2B AI39068 (S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic Acid 98% 250mg $25 2026-05-25 Buy
A2B AI39068 (S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic Acid 98% 100mg $19 2026-05-25 Buy
aablocks AA00HZI8 (S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic Acid 97% 5g $261 2026-05-29 Buy
aablocks AA00HZI8 (S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic Acid 97% 100mg $22 2026-05-29 Buy
aablocks AA00HZI8 (S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic Acid 97% 250mg $29 2026-05-29 Buy
aablocks AA00HZI8 (S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic Acid 97% 1g $72 2026-05-29 Buy
ACHEMBLOCK W167585 (S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid 97% 1G $120 2026-05-25 Buy
ACHEMBLOCK W167585 (S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid 97% 1G $120 2026-05-27 Buy
ACHEMBLOCK W167585 (S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid 97% 5G $445 2026-05-25 Buy
ACHEMBLOCK W167585 (S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid 97% 5G $445 2026-05-27 Buy
ACHEMBLOCK W167585 (S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid 97% 25G $1780 2026-05-25 Buy
ACHEMBLOCK W167585 (S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid 97% 25G $1780 2026-05-27 Buy
AHH MT-17275 (S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid 97% 5g $508 2026-05-26 Buy

Properties

Melting point :46-49 °C(lit.)
alpha :D24 -71.8± 0.6° (c = 3.28 in CH3OH)
Boiling point :95-97 °C0.05 mm Hg(lit.)
Density :1.303 g/mL at 25 °C(lit.)
refractive index :n20/D 1.474(lit.)
Flash point :>230 °F
storage temp. :2-8°C
solubility :Readily soluble in hexane, ether, THF, CH2Cl2, benzene.
form :Viscous Liquid or Low Melting Solid
pka :1.47±0.10(Predicted)
color :Clear colorless or white
Specific Gravity :1.303
optical activity :[α]20/D 73±1°, c = 2% in methanol
Sensitive :Hygroscopic
Merck :14,6280
BRN :3591561
InChI :1S/C10H9F3O3/c1-16-9(8(14)15,10(11,12)13)7-5-3-2-4-6-7/h2-6H,1H3,(H,14,15)/t9-/m0/s1
InChIKey :JJYKJUXBWFATTE-VIFPVBQESA-N
SMILES :CO[C@](C(O)=O)(c1ccccc1)C(F)(F)F
CAS DataBase Reference :17257-71-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid is used as a chiral derivatizing agent, it reacts with an alcohol or amine of unknown stereochemistry to form an ester or amide. The absolute configuration of the ester or amide is then determined by proton and/or 19F NMR spectroscopy.

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