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ChemicalBook >> CAS DataBase List >> 3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE

3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE

$110 - $2950
Product name: 3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE
CAS: 180637-89-2
MF: C22H24N2O2S
MW: 380.5
EINECS:
MDL Number:MFCD09751002
Synonyms:3-[[(2R)-1-Methyl-2-pyrrolidinyl]Methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole;3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE;(R)-3-[(1-Methyl-2-pyrrolidinyl)methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole;(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole;(R)-5-[(2-phenylsulfonyl)ethenyl]-3-(N-methylpyrrolidine-2-ylmethyl)-1H-indole;Eletriptan Impurity 23;1H-Indole, 3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethenyl]-;(R)5-(2-Benzenesulfonyl-vinyl)-3-(1-methyl-pyrrolidin-2-ylmethyl)-1H-indole

Price31 Properties Safety Information Description

31 prices

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Brand

aablocks
ACHEMBLOCK
AK Scientific
Alichem
American Custom Chemicals Corporation
Biosynth
Chemenu
Crysdot
Matrix Scientific
Medical Isotopes, Inc.
TRC
Usbiological

Package

2mg
5MG
10mg
0.01g
0.025g
25mg
0.05g
50mg
0.1g
100MG
0.25g
250.00mg
250mg
500mg
1g

Manufactureraablocks
Product numberAA00224H
Product description(R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
Packaging250mg
Price$325
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00224H
Product description(R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
Packaging500mg
Price$463
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00224H
Product description(R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
Packaging1g
Price$740
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberAD270273
Product description(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole 95%
Packaging100MG
Price$1850
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberAD270273
Product description(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole 95%
Packaging1G
Price$2950
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number9474AA
Product description(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole
Packaging250mg
Price$2551
Updated2021-12-16
Buy

ManufacturerAlichem
Product number180637892
Product description(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole
Packaging1g
Price$1630.72
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberAPN0000866
Product description(R)-3-[(1-METHYL-2-PYRROLIDINYL)METHYL]-5-[2-(PHENYLSULFONYL)ETHENYL]-1H-INDOLE 95.00%
Packaging5MG
Price$496.4
Updated2021-12-16
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ManufacturerBiosynth
Product numberFB18184
Product descriptionR-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
Packaging10mg
Price$363.5
Updated2021-12-16
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ManufacturerBiosynth
Product numberFB18184
Product descriptionR-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
Packaging2mg
Price$110
Updated2021-12-16
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ManufacturerBiosynth
Product numberFB18184
Product descriptionR-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
Packaging5mg
Price$199.9
Updated2021-12-16
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ManufacturerBiosynth
Product numberFB18184
Product descriptionR-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
Packaging25mg
Price$661
Updated2021-12-16
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ManufacturerBiosynth
Product numberFB18184
Product descriptionR-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
Packaging0.01g
Price$900
Updated2026-06-04
Buy

ManufacturerBiosynth
Product numberFB18184
Product descriptionR-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
Packaging0.025g
Price$900
Updated2026-06-04
Buy

ManufacturerBiosynth
Product numberFB18184
Product descriptionR-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
Packaging0.05g
Price$900
Updated2026-06-04
Buy

ManufacturerBiosynth
Product numberFB18184
Product descriptionR-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
Packaging0.1g
Price$900
Updated2026-06-04
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00224H	(R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole	250mg	$325	2026-05-28	Buy
aablocks	AA00224H	(R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole	500mg	$463	2026-05-28	Buy
aablocks	AA00224H	(R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole	1g	$740	2026-05-28	Buy
ACHEMBLOCK	AD270273	(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole 95%	100MG	$1850	2026-05-27	Buy
ACHEMBLOCK	AD270273	(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole 95%	1G	$2950	2026-05-27	Buy
AK Scientific	9474AA	(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole	250mg	$2551	2021-12-16	Buy
Alichem	180637892	(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)vinyl)-1H-indole	1g	$1630.72	2021-12-16	Buy
American Custom Chemicals Corporation	APN0000866	(R)-3-[(1-METHYL-2-PYRROLIDINYL)METHYL]-5-[2-(PHENYLSULFONYL)ETHENYL]-1H-INDOLE 95.00%	5MG	$496.4	2021-12-16	Buy
Biosynth	FB18184	R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole	10mg	$363.5	2021-12-16	Buy
Biosynth	FB18184	R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole	2mg	$110	2021-12-16	Buy
Biosynth	FB18184	R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole	5mg	$199.9	2021-12-16	Buy
Biosynth	FB18184	R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole	25mg	$661	2021-12-16	Buy
Biosynth	FB18184	R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole	0.01g	$900	2026-06-04	Buy
Biosynth	FB18184	R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole	0.025g	$900	2026-06-04	Buy
Biosynth	FB18184	R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole	0.05g	$900	2026-06-04	Buy
Biosynth	FB18184	R-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole	0.1g	$900	2026-06-04	Buy

Next Last

Properties

Boiling point :617.7±55.0 °C(Predicted)
Density :1.263
solubility :soluble in Dichloromethane, Dimethylformamide, Methanol
pka :16.92±0.30(Predicted)

Safety Information

Symbol(GHS):

Signal word:

Danger

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H317	May cause an allergic skin reaction	Sensitisation, Skin	Category 1	Warning	P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H318	Causes serious eye damage	Serious eye damage/eye irritation	Category 1	Danger	P280, P305+P351+P338, P310
H373	May cause damage to organs through prolonged or repeated exposure	Specific target organ toxicity, repeated exposure	Category 2	Warning	P260, P314, P501

Precautionary statements:

P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P272	Contaminated work clothing should not be allowed out of the workplace.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310	Immediately call a POISON CENTER or doctor/physician.
P314	Get medical advice/attention if you feel unwell.
P321	Specific treatment (see … on this label).
P330	Rinse mouth.
P333+P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P363	Wash contaminated clothing before reuse.
P501	Dispose of contents/container to..…

Description

(R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole is the free base of (R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole Hydrobromide (B120725), which is an impurity of Eletriptan (E505000). Eletriptan is a selective serotonin 5-HT1B and 5-HT1D receptor agonist and used to treat migraines (1,2,3). (R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole is also an intermediate in the synthesis of 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-1-[1-[3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-1H-indol-5-yl]-2-(phenylsulfonyl)ethyl]-5-[(1E)-2-(phenylsulfonyl)ethenyl]-1H-indole (M320195).

Suppliers and manufacturers

CONIER CHEM AND PHARMA LIMITED

SIMAGCHEM CORP

XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.

DAYANG CHEM (HANGZHOU) CO.,LTD

Mainchem Co., Ltd. J & K SCIENTIFIC LTD. Chemsky（shanghai）International Co.,Ltd. AN PharmaTech Co Ltd Nanjing crow LuNing pharmaceutical technology co., LTD Shenzhen Polymeri Biochemical Technology Co., Ltd.

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3-[((2R)-1-METHYLPYRROLIDIN-2-YL)METHYL]-5-[(E)-2-(PHENYLSULFONYL)VINYL]INDOLE

Properties

Safety Information

Description

Suppliers and manufacturers