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ChemicalBook >> CAS DataBase List >> 2-Pyrrolidinone

2-Pyrrolidinone

2-Pyrrolidinone price.
  • $12 - $2167.55
  • Product name: 2-Pyrrolidinone
  • CAS: 616-45-5
  • MF: C4H7NO
  • MW: 85.1
  • EINECS:210-483-1
  • MDL Number:MFCD00005270
  • Synonyms:-Tetrahydropyrrolone;zacyclopentan-2-one;α-PVR ;Piperidinic acid anhydride;gama-Butyrolactam;2-PYRROLIDINONE, 99+%;2-Pyrrolidinone,Certified;2-Pyrrolidone,>98%
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  • AK Scientific
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Biorbyt Ltd
  • Biosynth
  • Chem-Impex
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Thermo Scientific Chemicals
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  • Usbiological
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  • 20 mg
  • ManufacturerAK Scientific
  • Product numberJ50634
  • Product description2-Pyrrolidone 98%
  • Packaging5g
  • Price$12
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberH644
  • Product description2-Pyrrolidone 99.5%(GC)
  • Packaging5g
  • Price$16
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ50634
  • Product description2-Pyrrolidone 98%
  • Packaging25g
  • Price$16
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberH644
  • Product description2-Pyrrolidone 99.5%(GC)
  • Packaging25g
  • Price$22
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ50634
  • Product description2-Pyrrolidone 98%
  • Packaging100g
  • Price$24
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberH644
  • Product description2-Pyrrolidone
  • Packaging100g
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH644
  • Product description2-Pyrrolidone 99.5%(GC)
  • Packaging100g
  • Price$30
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ50634
  • Product description2-Pyrrolidone 98%
  • Packaging500g
  • Price$50
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberH644
  • Product description2-Pyrrolidone 99.5%(GC)
  • Packaging500g
  • Price$67
  • Updated2026-06-04
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0021919
  • Product description2-PYRROLIDONE 95.00%
  • Packaging500MG
  • Price$727.65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0021919
  • Product description2-PYRROLIDONE 95.00%
  • Packaging1G
  • Price$909.56
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR922249
  • Product description2-Pyrrolidone ≥95%
  • Packaging25g
  • Price$60
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR922249
  • Product description2-Pyrrolidone ≥95%
  • Packaging25g
  • Price$60
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR922249
  • Product description2-Pyrrolidone
  • Packaging100g
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR922249
  • Product description2-Pyrrolidone
  • Packaging25g
  • Price$44
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR922249
  • Product description2-Pyrrolidone ≥95%
  • Packaging5g
  • Price$21
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J50634 2-Pyrrolidone 98% 5g $12 2026-06-04 Buy
AK Scientific H644 2-Pyrrolidone 99.5%(GC) 5g $16 2026-06-04 Buy
AK Scientific J50634 2-Pyrrolidone 98% 25g $16 2026-06-04 Buy
AK Scientific H644 2-Pyrrolidone 99.5%(GC) 25g $22 2026-06-04 Buy
AK Scientific J50634 2-Pyrrolidone 98% 100g $24 2026-06-04 Buy
AK Scientific H644 2-Pyrrolidone 100g $27 2021-12-16 Buy
AK Scientific H644 2-Pyrrolidone 99.5%(GC) 100g $30 2026-06-04 Buy
AK Scientific J50634 2-Pyrrolidone 98% 500g $50 2026-06-04 Buy
AK Scientific H644 2-Pyrrolidone 99.5%(GC) 500g $67 2026-06-04 Buy
American Custom Chemicals Corporation CHM0021919 2-PYRROLIDONE 95.00% 500MG $727.65 2021-12-16 Buy
American Custom Chemicals Corporation CHM0021919 2-PYRROLIDONE 95.00% 1G $909.56 2021-12-16 Buy
Apolloscientific OR922249 2-Pyrrolidone ≥95% 25g $60 2026-06-04 Buy
Apolloscientific OR922249 2-Pyrrolidone ≥95% 25g $60 2026-06-04 Buy
Apolloscientific OR922249 2-Pyrrolidone 100g $66 2021-12-16 Buy
Apolloscientific OR922249 2-Pyrrolidone 25g $44 2021-12-16 Buy
Apolloscientific OR922249 2-Pyrrolidone ≥95% 5g $21 2026-06-04 Buy

Properties

Melting point :23-25 °C (lit.)
Boiling point :245 °C (lit.)
Density :1.12 g/mL at 25 °C (lit.)
vapor density :2.9 (vs air)
vapor pressure :0.04 hPa (20 °C)
refractive index :n20/D 1.487(lit.)
FEMA :4829 | 2-PYRROLIDONE
Flash point :>230 °F
storage temp. :2-8°C
solubility :H2O: miscible (completely)
pka :16.62±0.20(Predicted)
form :Liquid
color :Clear colorless to pale yellow
PH :9-11 (100g/l, H2O, 20℃)
explosive limit :1.8-16.6%(V)
biological source :synthetic
Water Solubility :miscible
Sensitive :Hygroscopic
Merck :14,8016
BRN :105241
Henry's Law Constant :9.3×103 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)
Stability :Hygroscopic
InChI :1S/C4H7NO/c6-4-2-1-3-5-4/h1-3H2,(H,5,6)
InChIKey :HNJBEVLQSNELDL-UHFFFAOYSA-N
SMILES :O=C1CCCN1
LogP :-0.71 at 20℃
Surface tension :46.31mN/m at 293.15K
CAS DataBase Reference :616-45-5(CAS DataBase Reference)
NIST Chemistry Reference :2-Pyrrolidinone(616-45-5)
EPA Substance Registry System :2-Pyrrolidinone (616-45-5)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

2-pyrrolidone carboxylic acid, also known as pyroglutamic acid, is a derivative of the glutamine and glutamate. It is contained in many kinds of proteins including bacteriorhodopsin. It is a nonessential nutrient which can be normally generated during the glutathione cycle process inside the human body. It is also contained in fruits and vegetables. Pyroglutamic acid has many physiological functions and healthy effects. Its L-form can increase the activity off neurotransmitter acetylcholine and can be used in the production of the neurotransmitters gramma-aminobutyric acid (GABA) as well as glycine. Based on this, L-pyroglutamic acid is beneficial to brain function, being capable of supporting memory and learning as well as alleviating anxiety. In addition, its sodium-form product (sodium pyroglutamate), as a humectant, can be used for dry skin and hair products.

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