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ChemicalBook >> CAS DataBase List >> (E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one

(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one

(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one price.
  • $71 - $1274
  • Product name: (E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one
  • CAS: 347323-96-0
  • MF: C22H17N3OS
  • MW: 371.45
  • EINECS:
  • MDL Number:MFCD02629172
  • Synonyms:(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one;ITX 3;2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]-thiazolo[3,2-a]benzimidazol-3(2H)-one;Trio N-Terminal RhoGEF Domain Inhibitor, ITX3 ;CS-1227;Trio N-Terminal RhoGEF Domain Inhibitor, ITX3 - CAS 347323-96-0 - Calbiochem;Thiazolo[3,2-a]benzimidazol-3(2H)-one, 2-[(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]-;ITX3 >=98% (HPLC)
42 prices
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  • aablocks
  • ACHEMBLOCK
  • American Custom Chemicals Corporation
  • Arctom
  • Chemenu
  • ChemScene
  • Crysdot
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
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  • Manufactureraablocks
  • Product numberAA00C6D9
  • Product description(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one ≥98%
  • Packaging5mg
  • Price$110
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C6D9
  • Product description(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one ≥98%
  • Packaging10mg
  • Price$179
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C6D9
  • Product description(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one ≥98%
  • Packaging25mg
  • Price$382
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C6D9
  • Product description(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one ≥98%
  • Packaging50mg
  • Price$708
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C6D9
  • Product description(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one ≥98%
  • Packaging100mg
  • Price$1274
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberY226699
  • Product descriptionITX3 97.00%
  • Packaging100MG
  • Price$470
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberY226699
  • Product descriptionITX3 97.00%
  • Packaging25MG
  • Price$170
  • Updated2026-05-27
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000979
  • Product descriptionITX3 95.00%
  • Packaging10MG
  • Price$502
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000979
  • Product descriptionITX3 95.00%
  • Packaging5MG
  • Price$456
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000979
  • Product descriptionITX3 95.00%
  • Packaging50MG
  • Price$856
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberHY-16663
  • Product descriptionITX3 98.60%
  • Packaging5mg
  • Price$71
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-16663
  • Product descriptionITX3 98.60%
  • Packaging5mg
  • Price$71
  • Updated2026-05-25
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  • ManufacturerArctom
  • Product numberHY-16663
  • Product descriptionITX3 98.60%
  • Packaging100mg
  • Price$570
  • Updated2026-05-25
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  • ManufacturerArctom
  • Product numberHY-16663
  • Product descriptionITX3 98.60%
  • Packaging100mg
  • Price$570
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-16663
  • Product descriptionITX3 98.60%
  • Packaging10mg
  • Price$128
  • Updated2026-05-25
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  • ManufacturerArctom
  • Product numberHY-16663
  • Product descriptionITX3 98.60%
  • Packaging10mg
  • Price$128
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00C6D9 (E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one ≥98% 5mg $110 2026-05-28 Buy
aablocks AA00C6D9 (E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one ≥98% 10mg $179 2026-05-28 Buy
aablocks AA00C6D9 (E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one ≥98% 25mg $382 2026-05-28 Buy
aablocks AA00C6D9 (E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one ≥98% 50mg $708 2026-05-28 Buy
aablocks AA00C6D9 (E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one ≥98% 100mg $1274 2026-05-28 Buy
ACHEMBLOCK Y226699 ITX3 97.00% 100MG $470 2026-05-27 Buy
ACHEMBLOCK Y226699 ITX3 97.00% 25MG $170 2026-05-27 Buy
American Custom Chemicals Corporation INB0000979 ITX3 95.00% 10MG $502 2021-12-16 Buy
American Custom Chemicals Corporation INB0000979 ITX3 95.00% 5MG $456 2021-12-16 Buy
American Custom Chemicals Corporation INB0000979 ITX3 95.00% 50MG $856 2021-12-16 Buy
Arctom HY-16663 ITX3 98.60% 5mg $71 2026-05-26 Buy
Arctom HY-16663 ITX3 98.60% 5mg $71 2026-05-25 Buy
Arctom HY-16663 ITX3 98.60% 100mg $570 2026-05-25 Buy
Arctom HY-16663 ITX3 98.60% 100mg $570 2026-05-26 Buy
Arctom HY-16663 ITX3 98.60% 10mg $128 2026-05-25 Buy
Arctom HY-16663 ITX3 98.60% 10mg $128 2026-05-26 Buy

Properties

Boiling point :589.5±60.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMSO: ≥4mg/mL
form :Yellow solid
pka :0.17±0.20(Predicted)
color :Light yellow to yellow
InChI :1S/C22H17N3OS/c1-14-12-16(15(2)24(14)17-8-4-3-5-9-17)13-20-21(26)25-19-11-7-6-10-18(19)23-22(25)27-20/h3-13H,1-2H3/b20-13+
InChIKey :SJMYMKPBODEZSH-DEDYPNTBSA-N
SMILES :Cc1cc(\C=C2\Sc3nc4ccccc4n3C2=O)c(C)n1-c5ccccc5

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

A selective inhibitor of TrioN RhoGEF activity. Has been shown to inhibit TrioN-mediated GTP exchange on RhoG and Rac1, formation of TrioN-induced cellular structures in REF52 fibroblasts and NGF-mediated neurite outgrowth in PC12 cells in vitro.

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