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ChemicalBook >> CAS DataBase List >> (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide

(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide

$9 - $10000
Product name: (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide
CAS: 368421-58-3
MF: C13H14F2N4OS
MW: 312.34
EINECS:609-299-8
MDL Number:MFCD28404611
Synonyms:(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide;NaMe:Isavuconazole interMediate 8;Isavuconazole intermediate 8;(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide Hydrate Hydrosulfate;(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMid;(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutraMide;Isavuconazole intermediate 8 ? ?(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramide;Isoxaconazole Intermediate 8

Price22 Properties Safety Information Description

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aablocks
ACHEMBLOCK
Alichem
Ambeed
Ark Pharm
Chemenu
ChemScene
Crysdot
Labseeker
Medical Isotopes, Inc.
TRC

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1mg
100mg
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1g
5g
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200g

Manufactureraablocks
Product numberAA00C6IF
Product description(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide ≥97%
Packaging250mg
Price$16
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00C6IF
Product description(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide ≥97%
Packaging1g
Price$38
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00C6IF
Product description(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide ≥97%
Packaging5g
Price$170
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00C6IF
Product description(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide ≥97%
Packaging25g
Price$407
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberL14649
Product description(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%
Packaging25G
Price$325
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberL14649
Product description(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%
Packaging100G
Price$965
Updated2026-05-27
Buy

ManufacturerAlichem
Product number368421583
Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide
Packaging5g
Price$280.8
Updated2021-12-16
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ManufacturerAmbeed
Product numberA401662
Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%
Packaging1g
Price$28
Updated2021-12-16
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ManufacturerAmbeed
Product numberA401662
Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%
Packaging100mg
Price$9
Updated2021-12-16
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ManufacturerAmbeed
Product numberA401662
Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%
Packaging250mg
Price$11
Updated2021-12-16
Buy

ManufacturerArk Pharm
Product numberP000096376
Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%
Packaging100mg
Price$17
Updated2021-12-16
Buy

ManufacturerArk Pharm
Product numberP000096376
Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%
Packaging250mg
Price$25
Updated2021-12-16
Buy

ManufacturerArk Pharm
Product numberP000096376
Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%
Packaging1g
Price$62
Updated2021-12-16
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ManufacturerChemenu
Product numberCM186290
Product description(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 98%
Packaging5g
Price$65
Updated2026-05-20
Buy

ManufacturerChemenu
Product numberCM186290
Product description(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 98%
Packaging5g
Price$65
Updated2026-05-26
Buy

ManufacturerChemenu
Product numberCM186290
Product description(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 95+%
Packaging100g
Price$815
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00C6IF	(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide ≥97%	250mg	$16	2026-05-28	Buy
aablocks	AA00C6IF	(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide ≥97%	1g	$38	2026-05-28	Buy
aablocks	AA00C6IF	(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide ≥97%	5g	$170	2026-05-28	Buy
aablocks	AA00C6IF	(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide ≥97%	25g	$407	2026-05-28	Buy
ACHEMBLOCK	L14649	(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%	25G	$325	2026-05-27	Buy
ACHEMBLOCK	L14649	(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%	100G	$965	2026-05-27	Buy
Alichem	368421583	(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide	5g	$280.8	2021-12-16	Buy
Ambeed	A401662	(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%	1g	$28	2021-12-16	Buy
Ambeed	A401662	(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%	100mg	$9	2021-12-16	Buy
Ambeed	A401662	(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%	250mg	$11	2021-12-16	Buy
Ark Pharm	P000096376	(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%	100mg	$17	2021-12-16	Buy
Ark Pharm	P000096376	(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%	250mg	$25	2021-12-16	Buy
Ark Pharm	P000096376	(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%	1g	$62	2021-12-16	Buy
Chemenu	CM186290	(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 98%	5g	$65	2026-05-20	Buy
Chemenu	CM186290	(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 98%	5g	$65	2026-05-26	Buy
Chemenu	CM186290	(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 95+%	100g	$815	2021-12-16	Buy

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Properties

Melting point :198-200oC
Boiling point :536.4±60.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :11.54±0.29(Predicted)
color :Off-White
InChI :InChI=1/C13H14F2N4OS/c1-8(12(16)21)13(20,5-19-7-17-6-18-19)10-4-9(14)2-3-11(10)15/h2-4,6-8,20H,5H2,1H3,(H2,16,21)/t8-,13+/s3
InChIKey :UWVOPVUWKIHGRF-MKHMJDPCNA-N
SMILES :C(=S)(N)[C@H](C)[C@](C1=CC(F)=CC=C1F)(O)CN1C=NC=N1 |&1:3,5,r|
CAS DataBase Reference :368421-58-3

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning		P264, P270, P301+P312, P330, P501

Precautionary statements:

P280	Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramide is an intermediate in the synthesis of Isavuconazole (I777830), an triazole based antifungal agent for the treatment of invasive fungal infections.

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Isavuconazonium sulfate

Suppliers and manufacturers

Zhengzhou Anbu Chem Co.,Ltd

(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide CAS:368421-58-3

ShenZhen H&D Pharmaceutical Technology Co., LTD

Isavuconazole Impurity 36 CAS:368421-58-3

Hebei Ganmiao New material Technology Co., LTD

$7.00
(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide CAS:368421-58-3

career henan chemical co

$100.00
(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide CAS:368421-58-3

Chengdu Aupone Pharmaceutical Co.Ltd.

Capot Chemical Co.,Ltd.

Shanghai Daken Advanced Materials Co.,Ltd

Beijing Cooperate Pharmaceutical Co.,Ltd

Henan Tianfu Chemical Co.,Ltd.

ATK CHEMICAL COMPANY LIMITED

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(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide

Properties

Safety Information

Description

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