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ChemicalBook >> CAS DataBase List >> 2-Methoxyethoxymethyl chloride

2-Methoxyethoxymethyl chloride

2-Methoxyethoxymethyl chloride price.
  • $10 - $3115.2
  • Product name: 2-Methoxyethoxymethyl chloride
  • CAS: 3970-21-6
  • MF: C4H9ClO2
  • MW: 124.57
  • EINECS:223-589-8
  • MDL Number:MFCD00000888
  • Synonyms:ALKOXYETHOXYMETHYLCHLORIDE;BETA-METHOXYETHOXYMETHYL CHLORIDE;ETHYLENE GLYCOL CHLOROMETHYL METHYL ETHER;1-(Chloromethoxy)-2-methoxyethane~MEM chloride;Alcoxyethoxymethylchloride;2-Methoxyethoxymethyl chloride, technical grade;2-METHOXYETHOXYMETHYL CHLORIDE;MEM Chlordie
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  • Manufactureraablocks
  • Product numberAA0033AV
  • Product description2-Methoxyethoxymethyl chloride ≥95%
  • Packaging5g
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0033AV
  • Product description2-Methoxyethoxymethyl chloride ≥95%
  • Packaging25g
  • Price$18
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0033AV
  • Product description2-Methoxyethoxymethyl chloride ≥95%
  • Packaging500g
  • Price$235
  • Updated2026-05-28
  • Buy
  • ManufacturerAHH
  • Product numberMT-05678
  • Product description1-Chloromethoxy-2-methoxyethane 94%
  • Packaging1000g
  • Price$835
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberMT-05678
  • Product description1-Chloromethoxy-2-methoxyethane 97%
  • Packaging1000g
  • Price$835
  • Updated2026-05-25
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  • ManufacturerAHH
  • Product numberMT-05678
  • Product description1-Chloromethoxy-2-methoxyethane 97%
  • Packaging1000g
  • Price$835
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product numberE935
  • Product description2-Methoxyethoxymethyl chloride 95%(GC)
  • Packaging500gG
  • Price$548
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberE935
  • Product description2-Methoxyethoxymethyl chloride 95%(GC)
  • Packaging100g
  • Price$172
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberE935
  • Product description2-Methoxyethoxymethyl chloride
  • Packaging100g
  • Price$174
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberE935
  • Product description2-Methoxyethoxymethyl chloride
  • Packaging5g
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberE935
  • Product description2-Methoxyethoxymethyl chloride 95%(GC)
  • Packaging5g
  • Price$22
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberE935
  • Product description2-Methoxyethoxymethyl chloride 95%(GC)
  • Packaging25g
  • Price$56
  • Updated2026-06-04
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  • ManufacturerApolloscientific
  • Product numberOR4841
  • Product description2,5-Dioxahexyl chloride tech
  • Packaging25g
  • Price$48
  • Updated2026-06-04
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  • ManufacturerApolloscientific
  • Product numberOR4841
  • Product description2,5-Dioxahexyl chloride tech
  • Packaging5g
  • Price$21
  • Updated2026-06-04
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  • ManufacturerApolloscientific
  • Product numberOR4841
  • Product description2,5-Dioxahexyl chloride tech
  • Packaging100g
  • Price$184
  • Updated2026-06-04
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  • ManufacturerApolloscientific
  • Product numberOR4841
  • Product description2,5-Dioxahexyl chloride tech
  • Packaging500g
  • Price$626
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0033AV 2-Methoxyethoxymethyl chloride ≥95% 5g $10 2026-05-28 Buy
aablocks AA0033AV 2-Methoxyethoxymethyl chloride ≥95% 25g $18 2026-05-28 Buy
aablocks AA0033AV 2-Methoxyethoxymethyl chloride ≥95% 500g $235 2026-05-28 Buy
AHH MT-05678 1-Chloromethoxy-2-methoxyethane 94% 1000g $835 2021-12-16 Buy
AHH MT-05678 1-Chloromethoxy-2-methoxyethane 97% 1000g $835 2026-05-25 Buy
AHH MT-05678 1-Chloromethoxy-2-methoxyethane 97% 1000g $835 2026-05-26 Buy
AK Scientific E935 2-Methoxyethoxymethyl chloride 95%(GC) 500gG $548 2026-06-04 Buy
AK Scientific E935 2-Methoxyethoxymethyl chloride 95%(GC) 100g $172 2026-06-04 Buy
AK Scientific E935 2-Methoxyethoxymethyl chloride 100g $174 2021-12-16 Buy
AK Scientific E935 2-Methoxyethoxymethyl chloride 5g $21 2021-12-16 Buy
AK Scientific E935 2-Methoxyethoxymethyl chloride 95%(GC) 5g $22 2026-06-04 Buy
AK Scientific E935 2-Methoxyethoxymethyl chloride 95%(GC) 25g $56 2026-06-04 Buy
Apolloscientific OR4841 2,5-Dioxahexyl chloride tech 25g $48 2026-06-04 Buy
Apolloscientific OR4841 2,5-Dioxahexyl chloride tech 5g $21 2026-06-04 Buy
Apolloscientific OR4841 2,5-Dioxahexyl chloride tech 100g $184 2026-06-04 Buy
Apolloscientific OR4841 2,5-Dioxahexyl chloride tech 500g $626 2026-06-04 Buy

Properties

Melting point :200-202 °C
Boiling point :50-52 °C/13 mmHg (lit.)
Density :1.091 g/mL at 25 °C (lit.)
refractive index :n20/D 1.427(lit.)
Flash point :>230 °F
storage temp. :2-8°C
solubility :Chloroform, Methanol
form :Liquid
Specific Gravity :1.091
color :Clear colorless to yellow
Water Solubility :It hydrolyzes with water.
Sensitive :Moisture Sensitive
BRN :1900576
Exposure limits :ACGIH: TWA 0.001 ppm
InChI :1S/C4H9ClO2/c1-6-2-3-7-4-5/h2-4H2,1H3
InChIKey :BIAAQBNMRITRDV-UHFFFAOYSA-N
SMILES :COCCOCCl
CAS DataBase Reference :3970-21-6(CAS DataBase Reference)
NIST Chemistry Reference :«BETA»-methoxyethoxymethyl chloride(3970-21-6)
EPA Substance Registry System :Ethane, 1-(chloromethoxy)-2-methoxy- (3970-21-6)

Safety Information

Symbol(GHS): Flame (GHS02)Skull and Crossbones (GHS06)Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

2-Methoxyethoxymethyl chloride, is used as selectively cleaved under aprotic conditions in the presence of a wide range of OH-protected reagents. It is used as an OH-protecting reagent. An examples of the target molecule MEM Chloride is the side chain of roxithromycin. It is also used in the protection of the OH groups in serine and threonine during peptide synthesis. Some of the other applications include have the ability to coordinate to metals, which is thought to accelerate the cleavage by Lewis acids. The chelating ability of the MEM ether also makes it useful as a stereodirecting group in organometallic reactions, first noted in the stereo controlled addition of ?-methoxyvinyllithium to a carbonyl in the synthesis of taxusin.

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