(4-Chloro-3-nitrophenyl)(4-(2-fluorophenyl)piperazin-1-yl)Methanone
|
- $36 - $2014
- Product name: (4-Chloro-3-nitrophenyl)(4-(2-fluorophenyl)piperazin-1-yl)Methanone
- CAS: 432020-20-7
- MF: C17H15ClFN3O3
- MW: 363.7707032
- EINECS:
- MDL Number:MFCD03575351
- Synonyms:(4-Chloro-3-nitrophenyl)(4-(2-fluorophenyl)piperazin-1-yl)Methanone;1-(4-Chloro-3-nitrobenzoyl)-4-(2-fluorophenyl)-piperazine;SID: 164348711;SMI481;Methanone, (4-chloro-3-nitrophenyl)[4-(2-fluorophenyl)-1-piperazinyl]-;NPPM 6748481;NPPM 6748-481;NPPM6748481
33 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Arctom
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100MG
- 250MG
- 1G
- Manufactureraablocks
- Product numberAA00DLWX
- Product descriptionSMI-481
- Packaging10mg
- Price$72
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DLWX
- Product descriptionSMI-481
- Packaging25mg
- Price$99
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DLWX
- Product descriptionSMI-481
- Packaging50mg
- Price$144
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DLWX
- Product descriptionSMI-481
- Packaging5mg
- Price$52
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DLWX
- Product descriptionSMI-481 ≥98%
- Packaging1mg
- Price$36
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY230561
- Product descriptionSMI481 98%
- Packaging1G
- Price$1405
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY230561
- Product descriptionSMI481 98%
- Packaging250MG
- Price$540
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY230561
- Product descriptionSMI481 98%
- Packaging100MG
- Price$270
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5232
- Product descriptionSMI481
- Packaging50mg
- Price$460
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCS-0009134
- Product descriptionNPPM 6748-481 >=98%
- Packaging5mg
- Price$38
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberCS-0009134
- Product descriptionNPPM 6748-481 >=98%
- Packaging50mg
- Price$143
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberCS-0009134
- Product descriptionNPPM 6748-481 >=98%
- Packaging100mg
- Price$210
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberCS-0009134
- Product descriptionNPPM 6748-481 >=98%
- Packaging10mg
- Price$60
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberCS-0009134
- Product descriptionNPPM 6748-481 >=98%
- Packaging25mg
- Price$98
- Updated2026-05-26
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2387
- Product descriptionSMI 481
- Packaging10mg
- Price$88
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2387
- Product descriptionSMI 481
- Packaging50mg
- Price$330
- Updated2026-05-19
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00DLWX | SMI-481 | 10mg | $72 | 2026-05-28 | Buy |
| aablocks | AA00DLWX | SMI-481 | 25mg | $99 | 2026-05-28 | Buy |
| aablocks | AA00DLWX | SMI-481 | 50mg | $144 | 2026-05-28 | Buy |
| aablocks | AA00DLWX | SMI-481 | 5mg | $52 | 2026-05-28 | Buy |
| aablocks | AA00DLWX | SMI-481 ≥98% | 1mg | $36 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y230561 | SMI481 98% | 1G | $1405 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y230561 | SMI481 98% | 250MG | $540 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y230561 | SMI481 98% | 100MG | $270 | 2026-05-27 | Buy |
| AK Scientific | SYN5232 | SMI481 | 50mg | $460 | 2021-12-16 | Buy |
| Arctom | CS-0009134 | NPPM 6748-481 >=98% | 5mg | $38 | 2026-05-26 | Buy |
| Arctom | CS-0009134 | NPPM 6748-481 >=98% | 50mg | $143 | 2026-05-26 | Buy |
| Arctom | CS-0009134 | NPPM 6748-481 >=98% | 100mg | $210 | 2026-05-26 | Buy |
| Arctom | CS-0009134 | NPPM 6748-481 >=98% | 10mg | $60 | 2026-05-26 | Buy |
| Arctom | CS-0009134 | NPPM 6748-481 >=98% | 25mg | $98 | 2026-05-26 | Buy |
| Axon Medchem | Axon2387 | SMI 481 | 10mg | $88 | 2026-05-19 | Buy |
| Axon Medchem | Axon2387 | SMI 481 | 50mg | $330 | 2026-05-19 | Buy |
Properties
Boiling point :543.3±50.0 °C(Predicted)
Density :1.411±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear
form :powder
pka :1.04±0.10(Predicted)
color :white to beige
InChI :1S/C17H15ClFN3O3/c18-13-6-5-12(11-16(13)22(24)25)17(23)21-9-7-20(8-10-21)15-4-2-1-3-14(15)19/h1-6,11H,7-10H2
InChIKey :LSPJXCGEFJDMHA-UHFFFAOYSA-N
SMILES :ClC1=C([N+]([O-])=O)C=C(C(N2CCN(C3=CC=CC=C3F)CC2)=O)C=C1
Density :1.411±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear
form :powder
pka :1.04±0.10(Predicted)
color :white to beige
InChI :1S/C17H15ClFN3O3/c18-13-6-5-12(11-16(13)22(24)25)17(23)21-9-7-20(8-10-21)15-4-2-1-3-14(15)19/h1-6,11H,7-10H2
InChIKey :LSPJXCGEFJDMHA-UHFFFAOYSA-N
SMILES :ClC1=C([N+]([O-])=O)C=C(C(N2CCN(C3=CC=CC=C3F)CC2)=O)C=C1
Safety Information
| Symbol(GHS): |
|
||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||||||||||||||||
| Hazard statements: |
|
||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Phosphatidylinositol (PtdIns) transfer proteins (PITPs) mediate the exchange of PtdIns and phosphatidylcholine between membranes, a step required for a wide array of cellular processes including cell division. SMI-481 is an inhibitor of the yeast PITP Sec14, blocking both Sec14-mediated transfer of [3H]-PtdIns in vitro and growth (IC50s = 0.21 and 2.87 μM, respectively). Suppression of Sec14 expression leads to proportional reduction in SMI-481 inhibition, suggesting that SMI-481 acts specifically through Sec14. Moreover, SMI-481 does not affect [3H]-PtdIns transfer mediated by other yeast PITPs.Related product price
Suppliers and manufacturers
Shaanxi Dideu New Materials Co. Ltd
TargetMol Chemicals Inc.
Aladdin Scientific
Amadis Chemical Company Limited
Guangzhou Isun Pharmaceutical Co., Ltd
SPIRO PHARMA
Pharmacodia (Beijing) Co.,Ltd
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
Lynnchem
NPPM 6748-481
CAS:432020-20-7