5-Hydroxy-1,4-naphthalenedione
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- $8 - $2120
- Product name: 5-Hydroxy-1,4-naphthalenedione
- CAS: 481-39-0
- MF: C10H6O3
- MW: 174.15
- EINECS:207-567-5
- MDL Number:MFCD00001684
- Synonyms:5-Hydroxy-p-naphthoquinone, 97% 5GR;Juglone(NSC 34266;NSC 622948);5-Hydroxy-1,4-naphthoquinone 97%;RARECHEM BW GC 0025;WALNUT EXTRACT, WATER SOLUBLE;1,4-Naphthalenedione,5-hydroxy- ;1,4-Naphthoquinone, 5-hydroxy-
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Brand
- aablocks
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- Arctom
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
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- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
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Package
- 1mg
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- 10mg
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- 10G
- 25g
- 5 g
- Manufactureraablocks
- Product numberAA00347F
- Product description5-Hydroxy-1，4-naphthalenedione 97%
- Packaging1mg
- Price$8
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00347F
- Product description5-Hydroxy-1，4-naphthalenedione ≥97%(GC)
- Packaging100mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00347F
- Product description5-Hydroxy-1，4-naphthalenedione 97%
- Packaging25mg
- Price$10
- Updated2026-05-28
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- Manufactureraablocks
- Product numberAA00347F
- Product description5-Hydroxy-1，4-naphthalenedione 97%
- Packaging250mg
- Price$16
- Updated2026-05-28
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- Manufactureraablocks
- Product numberAA00347F
- Product description5-Hydroxy-1，4-naphthalenedione 97%
- Packaging1g
- Price$19
- Updated2026-05-28
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- Manufactureraablocks
- Product numberAA00347F
- Product description5-Hydroxy-1，4-naphthalenedione 97%
- Packaging5g
- Price$44
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00347F
- Product description5-Hydroxy-1，4-naphthalenedione 98%
- Packaging25g
- Price$178
- Updated2026-05-28
- Buy
- ManufacturerAHH
- Product numberMT-15349
- Product description5-Hydroxy-1,4-naphthalenedione 97%
- Packaging25g
- Price$298
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-15349
- Product description5-Hydroxy-1,4-naphthalenedione 97%
- Packaging25g
- Price$298
- Updated2026-05-25
- Buy
- ManufacturerAHH
- Product numberMT-15349
- Product description5-Hydroxy-1,4-naphthalenedione 97%
- Packaging25g
- Price$298
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberV0179
- Product description5-Hydroxy-1,4-naphthoquinone
- Packaging1g
- Price$129
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHBL0000155
- Product descriptionJuglone 95.00%
- Packaging500MG
- Price$490
- Updated2021-12-16
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- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHBL0000155
- Product descriptionJuglone 95.00%
- Packaging5G
- Price$1150
- Updated2021-12-16
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- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHBL0000155
- Product descriptionJuglone 95.00%
- Packaging10G
- Price$1525
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHBL0000155
- Product descriptionJuglone 95.00%
- Packaging1G
- Price$647.6
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-N6949
- Product descriptionJuglone 99.77%
- Packaging100mg
- Price$281
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00347F | 5-Hydroxy-1，4-naphthalenedione 97% | 1mg | $8 | 2026-05-28 | Buy |
| aablocks | AA00347F | 5-Hydroxy-1，4-naphthalenedione ≥97%(GC) | 100mg | $10 | 2026-05-28 | Buy |
| aablocks | AA00347F | 5-Hydroxy-1，4-naphthalenedione 97% | 25mg | $10 | 2026-05-28 | Buy |
| aablocks | AA00347F | 5-Hydroxy-1，4-naphthalenedione 97% | 250mg | $16 | 2026-05-28 | Buy |
| aablocks | AA00347F | 5-Hydroxy-1，4-naphthalenedione 97% | 1g | $19 | 2026-05-28 | Buy |
| aablocks | AA00347F | 5-Hydroxy-1，4-naphthalenedione 97% | 5g | $44 | 2026-05-28 | Buy |
| aablocks | AA00347F | 5-Hydroxy-1，4-naphthalenedione 98% | 25g | $178 | 2026-05-28 | Buy |
| AHH | MT-15349 | 5-Hydroxy-1,4-naphthalenedione 97% | 25g | $298 | 2021-12-16 | Buy |
| AHH | MT-15349 | 5-Hydroxy-1,4-naphthalenedione 97% | 25g | $298 | 2026-05-25 | Buy |
| AHH | MT-15349 | 5-Hydroxy-1,4-naphthalenedione 97% | 25g | $298 | 2026-05-26 | Buy |
| AK Scientific | V0179 | 5-Hydroxy-1,4-naphthoquinone | 1g | $129 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HBL0000155 | Juglone 95.00% | 500MG | $490 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HBL0000155 | Juglone 95.00% | 5G | $1150 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HBL0000155 | Juglone 95.00% | 10G | $1525 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HBL0000155 | Juglone 95.00% | 1G | $647.6 | 2021-12-16 | Buy |
| Arctom | HY-N6949 | Juglone 99.77% | 100mg | $281 | 2026-05-26 | Buy |
Properties
Melting point :161-163 °C (lit.)
Boiling point :265.11°C (rough estimate)
Density :1.2346 (rough estimate)
refractive index :1.5036 (estimate)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :DMSO: 10 mg/ml; Ethanol: 10 mg/ml
form :Crystalline Powder
pka :6.59±0.20(Predicted)
color :Orange to brown
Water Solubility :SOLUBLE IN HOT WATER
Sensitive :Light Sensitive
Merck :14,5269
BRN :1909764
InChI :1S/C10H6O3/c11-7-4-5-9(13)10-6(7)2-1-3-8(10)12/h1-5,12H
InChIKey :KQPYUDDGWXQXHS-UHFFFAOYSA-N
SMILES :Oc1cccc2C(=O)C=CC(=O)c12
LogP :1.920
CAS DataBase Reference :481-39-0(CAS DataBase Reference)
NIST Chemistry Reference :1,4-Naphthalenedione, 5-hydroxy-(481-39-0)
EPA Substance Registry System :1,4-Naphthalenedione, 5-hydroxy- (481-39-0)
Boiling point :265.11°C (rough estimate)
Density :1.2346 (rough estimate)
refractive index :1.5036 (estimate)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :DMSO: 10 mg/ml; Ethanol: 10 mg/ml
form :Crystalline Powder
pka :6.59±0.20(Predicted)
color :Orange to brown
Water Solubility :SOLUBLE IN HOT WATER
Sensitive :Light Sensitive
Merck :14,5269
BRN :1909764
InChI :1S/C10H6O3/c11-7-4-5-9(13)10-6(7)2-1-3-8(10)12/h1-5,12H
InChIKey :KQPYUDDGWXQXHS-UHFFFAOYSA-N
SMILES :Oc1cccc2C(=O)C=CC(=O)c12
LogP :1.920
CAS DataBase Reference :481-39-0(CAS DataBase Reference)
NIST Chemistry Reference :1,4-Naphthalenedione, 5-hydroxy-(481-39-0)
EPA Substance Registry System :1,4-Naphthalenedione, 5-hydroxy- (481-39-0)
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Juglone is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. It has allelopathic actions, suppressing growth, photosynthesis, and respiration in plants and other organisms, although some bacteria can metabolize juglone. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 μM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms.Related product price
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