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ChemicalBook >> CAS DataBase List >> Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid

Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid

$4 - $3213.79
Product name: Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
CAS: 486460-00-8
MF: C15H18F3NO4
MW: 333.31
EINECS:691-120-8
MDL Number:MFCD06659147
Synonyms:Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,(bR)-;(R)-Sitagliptin N-Boc-Acid IMpurity;Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid (3R)-N-(tert-Butoxycarbonyl)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid;Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid, >=99%;(3R)-N-Boc-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid;(3R)-N-(tert-Butoxycarbonyl)-3-aMino-4-(2,4,5-trifluorophenyl)-butanoic acid- Boc-(R)-3-AMino-4-(2,4,5-trifluorophenyl) butanoic acid (BOC acid);[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-(R)-benzenebuta;(R)-Boc-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacid

Price44 Properties Safety Information Description

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aablocks
AccelPharmtech
Acrotein
AK Scientific
Alichem
Ambeed
American Custom Chemicals Corporation
Biosynth
Chemenu
Chem-Impex
ChemScene
Crysdot
Matrix Scientific
Synthonix
TRC

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Manufactureraablocks
Product numberAA0038M7
Product description(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid 98%
Packaging1g
Price$4
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0038M7
Product description(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid 98%
Packaging5g
Price$6
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0038M7
Product description(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid 98%
Packaging10g
Price$10
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0038M7
Product description(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid 98%
Packaging25g
Price$20
Updated2026-05-28
Buy

ManufacturerAccelPharmtech
Product numberQH1005
Product descriptionBOC-(R)-3-AMINO-4-(2,4,5-TRIFLUORO-pheNYL)-BUTYRIC ACID 99%
Packaging5G
Price$190
Updated2026-05-21
Buy

ManufacturerAcrotein
Product numberA-1307
Product descriptionN-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97%
Packaging250g
Price$229.6
Updated2026-05-25
Buy

ManufacturerAcrotein
Product numberA-1307
Product descriptionN-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97%
Packaging100g
Price$92.4
Updated2026-05-25
Buy

ManufacturerAcrotein
Product numberA-1307
Product descriptionN-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97%
Packaging25g
Price$107.25
Updated2021-12-16
Buy

ManufacturerAcrotein
Product numberA-1307
Product descriptionN-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97%
Packaging5g
Price$32.82
Updated2021-12-16
Buy

ManufacturerAcrotein
Product numberA-1307
Product descriptionN-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97%
Packaging25g
Price$34.3
Updated2026-05-25
Buy

ManufacturerAcrotein
Product numberA-1307
Product descriptionN-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97%
Packaging100g
Price$321.75
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product numberX1035
Product descriptionBoc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacid
Packaging25g
Price$147
Updated2021-12-16
Buy

ManufacturerAlichem
Product number486460008
Product descriptionBoc-(R)-3-AMino-4-(2,4,5-trifluorophenyl)butanoicacid
Packaging25g
Price$218.25
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA240774
Product description(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoicacid 98%
Packaging5g
Price$14
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA240774
Product description(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoicacid 98%
Packaging500g
Price$727
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberHCH0027721
Product description(3R)-N-(TERT-BUTOXYCARBONYL)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOIC ACID 95.00%
Packaging1G
Price$1212.75
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA0038M7	(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid 98%	1g	$4	2026-05-28	Buy
aablocks	AA0038M7	(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid 98%	5g	$6	2026-05-28	Buy
aablocks	AA0038M7	(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid 98%	10g	$10	2026-05-28	Buy
aablocks	AA0038M7	(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid 98%	25g	$20	2026-05-28	Buy
AccelPharmtech	QH1005	BOC-(R)-3-AMINO-4-(2,4,5-TRIFLUORO-pheNYL)-BUTYRIC ACID 99%	5G	$190	2026-05-21	Buy
Acrotein	A-1307	N-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97%	250g	$229.6	2026-05-25	Buy
Acrotein	A-1307	N-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97%	100g	$92.4	2026-05-25	Buy
Acrotein	A-1307	N-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97%	25g	$107.25	2021-12-16	Buy
Acrotein	A-1307	N-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97%	5g	$32.82	2021-12-16	Buy
Acrotein	A-1307	N-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97%	25g	$34.3	2026-05-25	Buy
Acrotein	A-1307	N-Boc-(R)-2,4,5-trifluoro-b-homophenylalanine 97%	100g	$321.75	2021-12-16	Buy
AK Scientific	X1035	Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacid	25g	$147	2021-12-16	Buy
Alichem	486460008	Boc-(R)-3-AMino-4-(2,4,5-trifluorophenyl)butanoicacid	25g	$218.25	2021-12-16	Buy
Ambeed	A240774	(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoicacid 98%	5g	$14	2021-12-16	Buy
Ambeed	A240774	(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoicacid 98%	500g	$727	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0027721	(3R)-N-(TERT-BUTOXYCARBONYL)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOIC ACID 95.00%	1G	$1212.75	2021-12-16	Buy

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Properties

Melting point :136-138℃
Boiling point :443.1±45.0 °C(Predicted)
Density :1.292±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka :4.30±0.10(Predicted)
form :Solid
color :White to Off-White
optical activity :25.305°(C=0.01g/ mI, CHCL3 , 20°C, 589nm)
InChI :InChI=1/C15H18F3NO4/c1-15(2,3)23-14(22)19-9(6-13(20)21)4-8-5-11(17)12(18)7-10(8)16/h5,7,9H,4,6H2,1-3H3,(H,19,22)(H,20,21)/t9-/s3
InChIKey :TUAXCHGULMWHIO-DJEYLCQNNA-N
SMILES :C(C1C=C(F)C(F)=CC=1F)[C@H](CC(=O)O)NC(=O)OC(C)(C)C |&1:10,r|

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning		P264, P280, P305+P351+P338,P337+P313P

Precautionary statements:

P305+P351+P338

IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Boc-(R) -3-amino-4 -(2,4, 5-trifluorophenyl) butyric acid is an important intermediate for the preparation of sitagliptin. Sitagliptinphosphate is the first dipeptidase -IV(dpp-4) inhibitor approved by FDA in 2006. It is used for the treatment of type II diabetes mellitus. It has obvious hypoglycemic effect when used alone or in combination with metformin and pioglitazone, and it is safe to take, well tolerated, with few adverse reactions.

More related product prices

ETHYLENE OXIDE Butyraldehyde Sebacic acid 2-Deoxy-L-ribose BOC-(R)-3-AMINO-4-(2-FLUORO-PHENYL)-BUTYRIC ACID BOC-(R)-3-AMINO-4-(3,4-DIFLUORO-PHENYL)-BUTYRIC ACID BOC-(R)-3-AMINO-4-(4-FLUORO-PHENYL)-BUTYRIC ACID 3-OXO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID METHYL ESTER Sitagliptin 243139-71-1 2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate 5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione 762240-92-6 762240-99-3 Sitagliptin Defuoro IMpurity 3 2,3,5-TRIFLUOROPHENYLACETIC ACID

Suppliers and manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

$10.00
BOC-(R)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID CAS:486460-00-8

Hangzhou ICH Biofarm Co., Ltd

(3R)-N-(tert-butoxycarbonyl)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid CAS:486460-00-8

Sinoway Industrial co., ltd.

Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid CAS:486460-00-8

Capot Chemical Co.,Ltd.

Beijing Cooperate Pharmaceutical Co.,Ltd

Hi-Tech Chemistry Corp

Henan Tianfu Chemical Co.,Ltd.

Shanghai Time Chemicals CO., Ltd.

Shanghai Yingrui Biopharma Co., Ltd.

ATK CHEMICAL COMPANY LIMITED

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Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers