3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone
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- $12 - $2097.8
- Product name: 3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone
- CAS: 491871-58-0
- MF: C18H11BrN2O2
- MW: 367.2
- EINECS:
- MDL Number:MFCD00276275
- Synonyms:3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone;TCS PIM-1 1;SC 204330;6-(5-Bromo-2-hydroxyphenyl)-1,2-dihydro-2-oxo-4-phenyl-3-pyridinecarbonitrile;TCS PIM-1;TCS PIM-1 1, >=98%;SC 204330; TCS PIM 1-1;CS-1482
59 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10mM(in 1mL DMSO)
- 5mg
- 10mM(in1mLDMSO)
- 10mg
- 10
- 1mg
- 10mM*1mLinDMSO
- 50
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 1000mg
- 5G
- Manufactureraablocks
- Product numberAA00DB4V
- Product description3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 98%
- Packaging25mg
- Price$71
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DB4V
- Product description3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 98%
- Packaging50mg
- Price$85
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DB4V
- Product description3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 98%
- Packaging100mg
- Price$102
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DB4V
- Product description3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 95%
- Packaging250mg
- Price$213
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DB4V
- Product description3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 95%
- Packaging1g
- Price$558
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DB4V
- Product description3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 98%
- Packaging10mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DB4V
- Product description3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 98%
- Packaging5mg
- Price$24
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DB4V
- Product description3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 98%
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65710
- Product description6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile 98%
- Packaging5G
- Price$1960
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65710
- Product description6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile 98%
- Packaging250MG
- Price$190
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65710
- Product description6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile 98%
- Packaging1G
- Price$490
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5483
- Product descriptionTCSPIM-11
- Packaging100mg
- Price$931
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ57518
- Product descriptionTCSPIM-11
- Packaging5mg
- Price$62
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA118376
- Product descriptionTCSPIM-11 98+%
- Packaging1g
- Price$657
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA118376
- Product descriptionTCSPIM-11 98+%
- Packaging1mg
- Price$27
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA118376
- Product descriptionTCSPIM-11 98+%
- Packaging5mg
- Price$46
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00DB4V | 3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 98% | 25mg | $71 | 2026-05-28 | Buy |
| aablocks | AA00DB4V | 3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 98% | 50mg | $85 | 2026-05-28 | Buy |
| aablocks | AA00DB4V | 3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 98% | 100mg | $102 | 2026-05-28 | Buy |
| aablocks | AA00DB4V | 3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 95% | 250mg | $213 | 2026-05-28 | Buy |
| aablocks | AA00DB4V | 3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 95% | 1g | $558 | 2026-05-28 | Buy |
| aablocks | AA00DB4V | 3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 98% | 10mg | $36 | 2026-05-28 | Buy |
| aablocks | AA00DB4V | 3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 98% | 5mg | $24 | 2026-05-28 | Buy |
| aablocks | AA00DB4V | 3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone 98% | 1mg | $12 | 2026-05-28 | Buy |
| ACHEMBLOCK | Q65710 | 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile 98% | 5G | $1960 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65710 | 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile 98% | 250MG | $190 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65710 | 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile 98% | 1G | $490 | 2026-05-27 | Buy |
| AK Scientific | SYN5483 | TCSPIM-11 | 100mg | $931 | 2021-12-16 | Buy |
| AK Scientific | J57518 | TCSPIM-11 | 5mg | $62 | 2021-12-16 | Buy |
| Ambeed | A118376 | TCSPIM-11 98+% | 1g | $657 | 2021-12-16 | Buy |
| Ambeed | A118376 | TCSPIM-11 98+% | 1mg | $27 | 2021-12-16 | Buy |
| Ambeed | A118376 | TCSPIM-11 98+% | 5mg | $46 | 2021-12-16 | Buy |
Properties
Boiling point :592.6±50.0 °C(Predicted)
Density :1.63±0.1 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :insoluble in H2O; insoluble in EtOH; ≥12.8 mg/mL in DMSO
form :solid
pka :6.93±0.10(Predicted)
color :Light yellow to yellow
Density :1.63±0.1 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :insoluble in H2O; insoluble in EtOH; ≥12.8 mg/mL in DMSO
form :solid
pka :6.93±0.10(Predicted)
color :Light yellow to yellow
Safety Information
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Description
The proto-oncogene serine/threonine-protein kinases, Pim-1 and Pim-2, are enzymes involved in cytokine signaling and participate in various signal transduction pathways, including cell growth, differentiation, and apoptosis. Their overexpression has been implicated in prostate cancer, some forms of leukemia, and lymphoma. TCS PIM-1 1 is an ATP-competitive Pim-1 kinase inhibitor (IC50 = 50 nM) that displays selectivity over the related kinases, Pim-2 and MEK1/2 (IC50s = >20 μM).Related product price
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