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ChemicalBook >> CAS DataBase List >> 5-Fluorouracil

5-Fluorouracil

5-Fluorouracil price.
  • $5 - $2970
  • Product name: 5-Fluorouracil
  • CAS: 51-21-8
  • MF: C4H3FN2O2
  • MW: 130.08
  • EINECS:200-085-6
  • MDL Number:MFCD00006018
  • Synonyms:2,4(1H,3H)-Pyrimidinedione, 5-fluoro-;2,4-dioxo-5-fluoropyrimidine ;3h)-pyrimidinedione,5-fluoro-4(1h ;5-faracil ;fluoro-uracile ;fluoro-uracilo ;fluorouracilum ;Fluracilum
142 prices
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  • Manufactureraablocks
  • Product numberAA003MP2
  • Product description5-Fluorouracil 98%
  • Packaging1g
  • Price$9
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003MP2
  • Product description5-Fluorouracil 98%
  • Packaging5g
  • Price$11
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003MP2
  • Product description5-Fluorouracil 98%
  • Packaging25g
  • Price$12
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003MP2
  • Product description5-Fluorouracil 98
  • Packaging50g
  • Price$18
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003MP2
  • Product description5-Fluorouracil 98
  • Packaging100g
  • Price$24
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003MP2
  • Product description5-Fluorouracil 98
  • Packaging250g
  • Price$54
  • Updated2026-05-28
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  • ManufacturerActivate Scientific
  • Product numberAS21439
  • Product description5-Fluorouracil 97%
  • Packaging25g
  • Price$27
  • Updated2026-06-04
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  • ManufacturerActivate Scientific
  • Product numberAS21439
  • Product description5-Fluorouracil 97%
  • Packaging5g
  • Price$18
  • Updated2026-06-04
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  • ManufacturerActivate Scientific
  • Product numberAS21439
  • Product description5-Fluorouracil 97%
  • Packaging100g
  • Price$78
  • Updated2026-06-04
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-F0140-G025
  • Product descriptionFluorouracil ≥97%(UV)
  • Packaging25g
  • Price$113
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-F0140-4025
  • Product descriptionFluorouracil ≥97%(UV)
  • Packaging4x25g
  • Price$338
  • Updated2026-05-06
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  • ManufacturerAHH
  • Product numberMT-51852
  • Product descriptionFluorouracil 97%
  • Packaging10g
  • Price$580
  • Updated2026-05-25
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  • Product numberMT-51852
  • Product descriptionFluorouracil 97%
  • Packaging10g
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  • ManufacturerAHH
  • Product numberMT-13743
  • Product description5-Fluorouracil 98%
  • Packaging1000g
  • Price$798
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberMT-13743
  • Product description5-Fluorouracil 97%
  • Packaging1000g
  • Price$798
  • Updated2026-05-25
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  • ManufacturerAHH
  • Product numberMT-13743
  • Product description5-Fluorouracil 97%
  • Packaging1000g
  • Price$798
  • Updated2026-05-26
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003MP2 5-Fluorouracil 98% 1g $9 2026-05-28 Buy
aablocks AA003MP2 5-Fluorouracil 98% 5g $11 2026-05-28 Buy
aablocks AA003MP2 5-Fluorouracil 98% 25g $12 2026-05-28 Buy
aablocks AA003MP2 5-Fluorouracil 98 50g $18 2026-05-28 Buy
aablocks AA003MP2 5-Fluorouracil 98 100g $24 2026-05-28 Buy
aablocks AA003MP2 5-Fluorouracil 98 250g $54 2026-05-28 Buy
Activate Scientific AS21439 5-Fluorouracil 97% 25g $27 2026-06-04 Buy
Activate Scientific AS21439 5-Fluorouracil 97% 5g $18 2026-06-04 Buy
Activate Scientific AS21439 5-Fluorouracil 97% 100g $78 2026-06-04 Buy
Adipogen Life Sciences CDX-F0140-G025 Fluorouracil ≥97%(UV) 25g $113 2026-05-06 Buy
Adipogen Life Sciences CDX-F0140-4025 Fluorouracil ≥97%(UV) 4x25g $338 2026-05-06 Buy
AHH MT-51852 Fluorouracil 97% 10g $580 2026-05-25 Buy
AHH MT-51852 Fluorouracil 97% 10g $580 2026-05-26 Buy
AHH MT-13743 5-Fluorouracil 98% 1000g $798 2021-12-16 Buy
AHH MT-13743 5-Fluorouracil 97% 1000g $798 2026-05-25 Buy
AHH MT-13743 5-Fluorouracil 97% 1000g $798 2026-05-26 Buy

Properties

Melting point :282-286 °C (dec.) (lit.)
Boiling point :190-200°C/0.1mmHg
Density :1.4593 (estimate)
storage temp. :2-8°C
solubility :H2O: 10 mg/mL, clear
form :powder
pka :pKa 8.0±0.1 (H2O) (Uncertain);3.0±0.1(H2O) (Uncertain)
color :white
PH :4.3-5.3 (10g/l, H2O, 20℃)
Water Solubility :12.2 g/L 20 ºC
Sensitive :Air Sensitive
Merck :14,4181
BRN :127172
Henry's Law Constant :5.8×104 mol/(m3Pa) at 25℃, HSDB (2015)
Stability :Stable. Light sensitive. Combustible. Incompatible with strong oxidizing agents, strong bases.
Major Application :diagnostic assay manufacturing
hematology
histology InChI :1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
InChIKey :GHASVSINZRGABV-UHFFFAOYSA-N
SMILES :FC1=CNC(=O)NC1=O
CAS DataBase Reference :51-21-8(CAS DataBase Reference)
IARC :3 (Vol. 26, Sup 7) 1987
NIST Chemistry Reference :2,4-Pyrimidinedione, 5-fluoro-(51-21-8)
EPA Substance Registry System :5-Fluorouracil (51-21-8)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

5-Fluorouracil is a pyrimadine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis. 5-Fluorouracil has been widely used to treat many gastrointestinal tract adenocarcinomas. However, its clinical application is greatly limited due to drug resistance.

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