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ChemicalBook >> CAS DataBase List >> N'-Nitro-L-arginine-methyl ester hydrochloride

N'-Nitro-L-arginine-methyl ester hydrochloride

N'-Nitro-L-arginine-methyl ester hydrochloride price.
  • $10 - $1787.5
  • Product name: N'-Nitro-L-arginine-methyl ester hydrochloride
  • CAS: 51298-62-5
  • MF: C7H16ClN5O4
  • MW: 269.69
  • EINECS:257-116-1
  • MDL Number:MFCD00039052
  • Synonyms:H-L-Arg(NO2)-OMe*HCl;H-Arg(NOZ)-OMe.HCl;methyl N5-[imino(nitroamino)methyl]-L-ornithine monohydrochloride ;H-Ala(NO2)-OMeHCl;H-Ala(No2)-Omecl;ω-Nitro-L-arginine methyl·hydrochloric acid;NG-Nitro-L-arginine-methyl ester hydrochloride,98%;Nω-Nitro-L-arginine methyl ester hydrochloride ,98%
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  • aablocks
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  • 10mM*1mLinWater(Solution)
  • 10mM*1mLinWater(Solid+Solvent)
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  • Manufactureraablocks
  • Product numberAA00I943
  • Product descriptionNG-Nitroarginine methyl ester hydrochloride ≥98%
  • Packaging250mg
  • Price$10
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I943
  • Product descriptionNG-Nitroarginine methyl ester hydrochloride 96%
  • Packaging5g
  • Price$23
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I943
  • Product descriptionNG-Nitroarginine methyl ester hydrochloride 95%
  • Packaging1g
  • Price$16
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I943
  • Product descriptionNG-Nitroarginine methyl ester hydrochloride 97%
  • Packaging25g
  • Price$41
  • Updated2026-05-29
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  • Manufactureraablocks
  • Product numberAA00I943
  • Product descriptionNG-Nitroarginine methyl ester hydrochloride 97%
  • Packaging100g
  • Price$153
  • Updated2026-05-29
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  • ManufacturerActivate Scientific
  • Product numberAS112931
  • Product descriptionH-Arg(NO2)-OMe.HCl 98%
  • Packaging100g
  • Price$333
  • Updated2021-12-16
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  • ManufacturerActivate Scientific
  • Product numberAS112931
  • Product descriptionH-Arg(NO2)-OMe.HCl 98%
  • Packaging5G
  • Price$26
  • Updated2021-12-16
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  • ManufacturerActivate Scientific
  • Product numberAS112931
  • Product descriptionH-Arg(NO2)-OMe.HCl 98%
  • Packaging25g
  • Price$104
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberMT-52238
  • Product descriptionH-Ala(NO2)-OMehydrochloride 99%
  • Packaging10g
  • Price$330
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberMT-52238
  • Product descriptionH-Ala(NO2)-OMe hydrochloride 97%
  • Packaging10g
  • Price$330
  • Updated2026-05-25
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  • ManufacturerAHH
  • Product numberMT-52238
  • Product descriptionH-Ala(NO2)-OMe hydrochloride 97%
  • Packaging10g
  • Price$330
  • Updated2026-05-26
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  • ManufacturerAK Scientific
  • Product numberJ51453
  • Product descriptionNω-Nitro-L-arginine methyl ester hydrochloride
  • Packaging100g
  • Price$190
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberV1206
  • Product descriptionN-Nitro-L-arginine methyl ester hydrochloride 98%(HPLC)
  • Packaging25g
  • Price$89
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ51453
  • Product descriptionN-Nitro-L-arginine methyl ester hydrochloride 95%
  • Packaging25g
  • Price$69
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ51453
  • Product descriptionN-Nitro-L-arginine methyl ester hydrochloride 95%
  • Packaging5g
  • Price$29
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberV1206
  • Product descriptionN-Nitro-L-arginine methyl ester hydrochloride 98%(HPLC)
  • Packaging5g
  • Price$39
  • Updated2026-06-04
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00I943 NG-Nitroarginine methyl ester hydrochloride ≥98% 250mg $10 2026-05-29 Buy
aablocks AA00I943 NG-Nitroarginine methyl ester hydrochloride 96% 5g $23 2026-05-29 Buy
aablocks AA00I943 NG-Nitroarginine methyl ester hydrochloride 95% 1g $16 2026-05-29 Buy
aablocks AA00I943 NG-Nitroarginine methyl ester hydrochloride 97% 25g $41 2026-05-29 Buy
aablocks AA00I943 NG-Nitroarginine methyl ester hydrochloride 97% 100g $153 2026-05-29 Buy
Activate Scientific AS112931 H-Arg(NO2)-OMe.HCl 98% 100g $333 2021-12-16 Buy
Activate Scientific AS112931 H-Arg(NO2)-OMe.HCl 98% 5G $26 2021-12-16 Buy
Activate Scientific AS112931 H-Arg(NO2)-OMe.HCl 98% 25g $104 2021-12-16 Buy
AHH MT-52238 H-Ala(NO2)-OMehydrochloride 99% 10g $330 2021-12-16 Buy
AHH MT-52238 H-Ala(NO2)-OMe hydrochloride 97% 10g $330 2026-05-25 Buy
AHH MT-52238 H-Ala(NO2)-OMe hydrochloride 97% 10g $330 2026-05-26 Buy
AK Scientific J51453 Nω-Nitro-L-arginine methyl ester hydrochloride 100g $190 2021-12-16 Buy
AK Scientific V1206 N-Nitro-L-arginine methyl ester hydrochloride 98%(HPLC) 25g $89 2026-06-04 Buy
AK Scientific J51453 N-Nitro-L-arginine methyl ester hydrochloride 95% 25g $69 2026-06-04 Buy
AK Scientific J51453 N-Nitro-L-arginine methyl ester hydrochloride 95% 5g $29 2026-06-04 Buy
AK Scientific V1206 N-Nitro-L-arginine methyl ester hydrochloride 98%(HPLC) 5g $39 2026-06-04 Buy

Properties

Melting point :157-161 °C (dec.)
alpha :14.5 º (c=3, CH3OH)
RTECS :RM2982570
refractive index :15 ° (C=3, MeOH)
storage temp. :-20°C
solubility :H2O: 50 mg/mL
form :powder
color :white to off-white
biological source :synthetic
Water Solubility :almost transparency
BRN :3744166
InChI :1S/C7H15N5O4.ClH/c1-16-6(13)5(8)3-2-4-10-7(9)11-12(14)15;/h5H,2-4,8H2,1H3,(H3,9,10,11);1H/t5-;/m0./s1
InChIKey :QBNXAGZYLSRPJK-JEDNCBNOSA-N
SMILES :Cl.COC(=O)[C@@H](N)CCCNC(=N)N[N+]([O-])=O
CAS DataBase Reference :51298-62-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

L-NAME requires hydrolysis of the methyl ester by cellular esterases to become a fully functional inhibitor (L-NNA). L-NNA exhibits some selectivity for inhibition of neuronal and endothelial isoforms. It exhibits Ki values of 15 nM, 39 nM, and 4.4 μM for nNOS (bovine), eNOS (human), and iNOS (mouse), respectively. The reported Ki value for the inhibition of iNOS ranges from 4-65 μM. L-NAME inhibits cGMP formation in endothelial cells with an IC50 of 3.1 μM (in the presence of 30 μM arginine) and reverses the vasodilation effects of acetylcholine in rat aorta rings with an EC50 of 0.54 μM.

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