1,3,5[10]-ESTRATRIENE-3,16ALPHA-DIOL-17-ONE
![1,3,5[10]-ESTRATRIENE-3,16ALPHA-DIOL-17-ONE price.](/CAS/GIF/566-76-7.gif)
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- $120 - $2960
- Product name: 1,3,5[10]-ESTRATRIENE-3,16ALPHA-DIOL-17-ONE
- CAS: 566-76-7
- MF: C18H22O3
- MW: 286.37
- EINECS:
- MDL Number:MFCD00870436
- Synonyms:1,3,5(10)-ESTRATRIEN-3,16-ALPHA-DIOL-17-ONE;3,16ALPHA-DIHYDROXY-1,3,5[10]-ESTRATRIEN-17-ONE;(16R)-3,16α-Dihydroxy-1,3,5(10)-estratriene-17-one;16α-OHE1;3,16α-Dihydroxy-1,3,5(10)-estratrien-17-one;C05300;(16α)-3,16-Dihydroxyestra-1,3,5(10)-trien-17-one;Estra-1,3,5(10)-triene-3,16α-diol-17-one
39 prices
Selected condition：
Brand
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- Biosynth
- Cayman Chemical
- ChemScene
- IsoSciences
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 2mg
- 2.5MG
- 1MG
- 1mL(100ug/mL)
- 5MG
- 10mg
- 25MG
- 50mg
- 100mg
- 1ML
- ManufacturerACHEMBLOCK
- Product numberX211455
- Product description16Alpha-Hydroxyestrone 98%
- Packaging5MG
- Price$625
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX211455
- Product description16Alpha-Hydroxyestrone 98%
- Packaging25MG
- Price$2015
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberZ1964
- Product description16-HydroxyEstrone
- Packaging10mg
- Price$835
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007053
- Product description1,3,5[10]-ESTRATRIENE-3,16-ALPHA-DIOL-17-ONE 95.00%
- Packaging25MG
- Price$1400
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007053
- Product description1,3,5[10]-ESTRATRIENE-3,16-ALPHA-DIOL-17-ONE 95.00%
- Packaging1MG
- Price$485
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007053
- Product description1,3,5[10]-ESTRATRIENE-3,16-ALPHA-DIOL-17-ONE 95.00%
- Packaging2.5MG
- Price$525
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFH59537
- Product description16a-Hydroxy estrone
- Packaging10mg
- Price$1427.8
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFH59537
- Product description16a-Hydroxy estrone
- Packaging25mg
- Price$2758.25
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFH59537
- Product description16a-Hydroxy estrone
- Packaging1mg
- Price$900
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFH59537
- Product description16a-Hydroxy estrone
- Packaging2mg
- Price$900
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFH59537
- Product description16a-Hydroxy estrone
- Packaging5mg
- Price$908.6
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number15208
- Product description16α-hydroxy Estrone ≥98%
- Packaging10mg
- Price$662
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15208
- Product description16α-hydroxy Estrone ≥98%
- Packaging5mg
- Price$466
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number15208
- Product description16α-hydroxy Estrone ≥98%
- Packaging10mg
- Price$729
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number15208
- Product description16α-hydroxy Estrone ≥98%
- Packaging1mg
- Price$121
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15208
- Product description16α-hydroxy Estrone ≥98%
- Packaging1mg
- Price$134
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | X211455 | 16Alpha-Hydroxyestrone 98% | 5MG | $625 | 2026-05-27 | Buy |
| ACHEMBLOCK | X211455 | 16Alpha-Hydroxyestrone 98% | 25MG | $2015 | 2026-05-27 | Buy |
| AK Scientific | Z1964 | 16-HydroxyEstrone | 10mg | $835 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007053 | 1,3,5[10]-ESTRATRIENE-3,16-ALPHA-DIOL-17-ONE 95.00% | 25MG | $1400 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007053 | 1,3,5[10]-ESTRATRIENE-3,16-ALPHA-DIOL-17-ONE 95.00% | 1MG | $485 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007053 | 1,3,5[10]-ESTRATRIENE-3,16-ALPHA-DIOL-17-ONE 95.00% | 2.5MG | $525 | 2021-12-16 | Buy |
| Biosynth | FH59537 | 16a-Hydroxy estrone | 10mg | $1427.8 | 2026-06-04 | Buy |
| Biosynth | FH59537 | 16a-Hydroxy estrone | 25mg | $2758.25 | 2026-06-04 | Buy |
| Biosynth | FH59537 | 16a-Hydroxy estrone | 1mg | $900 | 2026-06-04 | Buy |
| Biosynth | FH59537 | 16a-Hydroxy estrone | 2mg | $900 | 2026-06-04 | Buy |
| Biosynth | FH59537 | 16a-Hydroxy estrone | 5mg | $908.6 | 2026-06-04 | Buy |
| Cayman Chemical | 15208 | 16α-hydroxy Estrone ≥98% | 10mg | $662 | 2024-03-01 | Buy |
| Cayman Chemical | 15208 | 16α-hydroxy Estrone ≥98% | 5mg | $466 | 2026-04-30 | Buy |
| Cayman Chemical | 15208 | 16α-hydroxy Estrone ≥98% | 10mg | $729 | 2026-04-30 | Buy |
| Cayman Chemical | 15208 | 16α-hydroxy Estrone ≥98% | 1mg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 15208 | 16α-hydroxy Estrone ≥98% | 1mg | $134 | 2026-04-30 | Buy |
Properties
Melting point :209-211°C
Boiling point :493.2±45.0 °C(Predicted)
Density :1.249±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
form :Solid
pka :10.23±0.60(Predicted)
color :White to Light Beige
Boiling point :493.2±45.0 °C(Predicted)
Density :1.249±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
form :Solid
pka :10.23±0.60(Predicted)
color :White to Light Beige
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
The naturally-occurring estrogens are estrone (E1, ), estradiol (E2, ), and estriol (E3, ). 16α-hydroxy Estrone (16α-OHE1) is a hydroxylated metabolite of E1 as well as an interconversion product with E2. E1 is 16α-hydroxylated by cytochrome P450 (CYP) isoforms, including CYP1A1, CYP3A5, CYP3A4, and CYP3A7, with CYP3A5 being breast-specific. 16α-OHE1 is sulphatized or glucuronidated before excretion. It is increased in rheumatoid arthritis and decreased by physical activity. Unlike the parent estrogens and other hydroxylated metabolites of E1, 16α-OHE1 binds covalently and persistently activates estrogen receptors. In addition, this metabolite increases cell proliferation and does not suppress TNF-α secretion, whereas other estrogen metabolites are not pro-proliferative and have marked effects on TNF-α secretion. The levels of 16α-OHE1 are increased in some forms of hormone therapy. Because hormone therapy increases breast cancer risk, 16α-OHE1 has been implicated as a risk factor for breast cancer, although supportive data remains elusive.More related product prices
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