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ChemicalBook >> CAS DataBase List >> N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-aMine

N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-aMine

N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-aMine price.
  • $10 - $5372
  • Product name: N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-aMine
  • CAS: 662163-81-7
  • MF: C20H22N4
  • MW: 318.42
  • EINECS:
  • MDL Number:MFCD04077630
  • Synonyms:N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-aMine;CS-2426;ImportazoL;4-Quinazolinamine, N-(1-phenylethyl)-2-(1-pyrrolidinyl)-;Apoptosis,Importazole,Inhibitor,inhibit;Importazole, nuclear transport receptor importin-beta inhibitor;Importazole, 10 mM in DMSO;N-(1-benzenethyl)-2-(pyrolidine-1-yl)quinolineazoleline-4-amine
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  • Manufactureraablocks
  • Product numberAA00FHV4
  • Product descriptionN-(1-phenylethyl)-2-(1-pyrrolidinyl)-4-quinazolinamine 99%
  • Packaging100mg
  • Price$102
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00FHV4
  • Product descriptionN-(1-phenylethyl)-2-(1-pyrrolidinyl)-4-quinazolinamine 99%
  • Packaging250mg
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  • Manufactureraablocks
  • Product numberAA00FHV4
  • Product descriptionN-(1-phenylethyl)-2-(1-pyrrolidinyl)-4-quinazolinamine 99%
  • Packaging10mg
  • Price$23
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00FHV4
  • Product descriptionN-(1-phenylethyl)-2-(1-pyrrolidinyl)-4-quinazolinamine 99%
  • Packaging5mg
  • Price$17
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00FHV4
  • Product descriptionN-(1-phenylethyl)-2-(1-pyrrolidinyl)-4-quinazolinamine 99%
  • Packaging1mg
  • Price$10
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberQ65791
  • Product descriptionN-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-amine 98%
  • Packaging100MG
  • Price$105
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberQ65791
  • Product descriptionN-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-amine 98%
  • Packaging250MG
  • Price$210
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberQ65791
  • Product descriptionN-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-amine 98%
  • Packaging1G
  • Price$540
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product number4806CJ
  • Product descriptionImportazole
  • Packaging250mg
  • Price$330
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA528010
  • Product descriptionImportazole 98+%
  • Packaging5mg
  • Price$55
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  • ManufacturerAmbeed
  • Product numberA528010
  • Product descriptionImportazole 98+%
  • Packaging25mg
  • Price$158
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA528010
  • Product descriptionImportazole 98+%
  • Packaging10mg
  • Price$93
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA528010
  • Product descriptionImportazole 98+%
  • Packaging1g
  • Price$5372
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA4643
  • Product descriptionImportazole
  • Packaging10mg
  • Price$71
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberA4643
  • Product descriptionImportazole
  • Packaging25mg
  • Price$164
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberA4643
  • Product descriptionImportazole
  • Packaging50mg
  • Price$285
  • Updated2026-05-06
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00FHV4 N-(1-phenylethyl)-2-(1-pyrrolidinyl)-4-quinazolinamine 99% 100mg $102 2026-05-28 Buy
aablocks AA00FHV4 N-(1-phenylethyl)-2-(1-pyrrolidinyl)-4-quinazolinamine 99% 250mg $171 2026-05-28 Buy
aablocks AA00FHV4 N-(1-phenylethyl)-2-(1-pyrrolidinyl)-4-quinazolinamine 99% 10mg $23 2026-05-28 Buy
aablocks AA00FHV4 N-(1-phenylethyl)-2-(1-pyrrolidinyl)-4-quinazolinamine 99% 5mg $17 2026-05-28 Buy
aablocks AA00FHV4 N-(1-phenylethyl)-2-(1-pyrrolidinyl)-4-quinazolinamine 99% 1mg $10 2026-05-28 Buy
ACHEMBLOCK Q65791 N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-amine 98% 100MG $105 2026-05-27 Buy
ACHEMBLOCK Q65791 N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-amine 98% 250MG $210 2026-05-27 Buy
ACHEMBLOCK Q65791 N-(1-phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-amine 98% 1G $540 2026-05-27 Buy
AK Scientific 4806CJ Importazole 250mg $330 2021-12-16 Buy
Ambeed A528010 Importazole 98+% 5mg $55 2021-12-16 Buy
Ambeed A528010 Importazole 98+% 25mg $158 2021-12-16 Buy
Ambeed A528010 Importazole 98+% 10mg $93 2021-12-16 Buy
Ambeed A528010 Importazole 98+% 1g $5372 2021-12-16 Buy
ApexBio Technology A4643 Importazole 10mg $71 2026-05-06 Buy
ApexBio Technology A4643 Importazole 25mg $164 2026-05-06 Buy
ApexBio Technology A4643 Importazole 50mg $285 2026-05-06 Buy

Properties

Boiling point :516.8±42.0 °C(Predicted)
Density :1+-.0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >5mg/mL
pka :7.27±0.59(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :1S/C20H22N4/c1-15(16-9-3-2-4-10-16)21-19-17-11-5-6-12-18(17)22-20(23-19)24-13-7-8-14-24/h2-6,9-12,15H,7-8,13-14H2,1H3,(H,21,22,23)
InChIKey :HKGJEZIGDHFJFL-UHFFFAOYSA-N
SMILES :CC(C1=CC=CC=C1)NC2=NC(N3CCCC3)=NC4=C2C=CC=C4

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Importazole is a cell-permeable inhibitor of importin-β, which transports cargo molecules bearing a nuclear localization signal into the nucleus. Importazole prevents nuclear import of GFP-tagged nuclear factor of activated T cells (NFAT-GFP) in HEK293 cells (IC50 = 15 μM), which is reversible upon importazole washout. Importazole does not interfere with transportin-mediated nuclear import or chromosomal maintenance 1 (CRM1)-mediated nuclear export. Importazole inhibits nuclear import of topoisomerase IIβ binding protein 1 (TopBP1) in Xenopus egg extracts and of NF-κB in multiple myeloma cells. It also induces defects in spindle and microtubule formation in vitro.

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