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ChemicalBook >> CAS DataBase List >> 3-(1-METHYL-4-PHENYLACETYL-1H-2-PYRROLYL)-N-HYDROXY-2-PROPENAMIDE

3-(1-METHYL-4-PHENYLACETYL-1H-2-PYRROLYL)-N-HYDROXY-2-PROPENAMIDE

3-(1-METHYL-4-PHENYLACETYL-1H-2-PYRROLYL)-N-HYDROXY-2-PROPENAMIDE price.
  • $62 - $199
  • Product name: 3-(1-METHYL-4-PHENYLACETYL-1H-2-PYRROLYL)-N-HYDROXY-2-PROPENAMIDE
  • CAS: 676599-90-9
  • MF: C16H16N2O3
  • MW: 284.31
  • EINECS:
  • MDL Number:MFCD05865226
  • Synonyms:3-(1-METHYL-4-PHENYLACETYL-1H-2-PYRROLYL)-N-HYDROXY-2-PROPENAMIDE;APHA COMPOUND 8;(E)-N-hydroxy-3-(1-Methyl-4-(2-phenylacetyl)-1H-pyrrol-2-yl)acrylaMide;2-Propenamide, N-hydroxy-3-[1-methyl-4-(2-phenylacetyl)-1H-pyrrol-2-yl]-;APHA-8;Aroyl pyrrole hydroxy amide #8;MC 1353;MC1353
4 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • Sigma-Aldrich
Package
  • 500μg
  • 1mg
  • ManufacturerAK Scientific
  • Product number3575DN
  • Product description3-(1-Methyl-4-phenylacetyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide
  • Packaging1mg
  • Price$199
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21228
  • Product descriptionAPHA Compound 8
  • Packaging500μg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21228
  • Product descriptionAPHA Compound 8
  • Packaging1mg
  • Price$92
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberA2478
  • Product descriptionAPHA Compound 8 ≥98% (HPLC), solid
  • Packaging1mg
  • Price$175
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3575DN 3-(1-Methyl-4-phenylacetyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide 1mg $199 2021-12-16 Buy
Cayman Chemical 21228 APHA Compound 8 500μg $62 2024-03-01 Buy
Cayman Chemical 21228 APHA Compound 8 1mg $92 2024-03-01 Buy
Sigma-Aldrich A2478 APHA Compound 8 ≥98% (HPLC), solid 1mg $175 2026-04-30 Buy

Properties

storage temp. :2-8°C
solubility :DMSO: 10 mg/mL, soluble
form :solid
InChI :1S/C16H16N2O3/c1-18-11-13(10-14(18)7-8-16(20)17-21)15(19)9-12-5-3-2-4-6-12/h2-8,10-11,21H,9H2,1H3,(H,17,20)/b8-7+
InChIKey :UFQOXIMRSMFQRI-BQYQJAHWSA-N
SMILES :Cn1cc(cc1\C=C\C(=O)NO)C(=O)Cc2ccccc2

Safety Information

Symbol(GHS): Corrosion (GHS05)Exclamation Mark (GHS07)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.

Description

APHA Compound 8 is a synthetic HDAC (histone deacetylase) inhibitor. It induces histone hyperacetylation, growth inhibition, and terminal cell differentiation.

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