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ChemicalBook >> CAS DataBase List >> 7,8-Dihydroxycoumarin

7,8-Dihydroxycoumarin

7,8-Dihydroxycoumarin price.
  • $20 - $2596
  • Product name: 7,8-Dihydroxycoumarin
  • CAS: 486-35-1
  • MF: C9H6O4
  • MW: 178.14
  • EINECS:207-632-8
  • MDL Number:MFCD00016977
  • Synonyms:7,8-DIHYDROXY-2H-1-BENZOPYRAN-2-ONE;7,8-DIHYDROXY-CHROMEN-2-ONE;7,8-DIHYDROXYCOUMARIN;AKOS 213-37;7,8-dihydroxy-2h-1-benzopyran-2-on ;7,8-dihydroxy-coumari ;7,8-Diydroxycoumarin;Daphetin
114 prices
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  • aablocks
  • ACHEMBLOCK
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
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  • Ark Pharm
  • AvaChem
  • Biorbyt Ltd
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  • ChemScene
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  • TCI Chemical
  • TRC
  • Usbiological
Package
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  • 20mg
  • 25mg
  • 100mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mg
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  • 10mM*1mLinDMSO(Solution)
  • 1mlx10mM(inDMSO)
  • 250.00mg
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  • 10 mg
  • Manufactureraablocks
  • Product numberAA00IKGX
  • Product descriptionDaphnetin 95%
  • Packaging100mg
  • Price$33
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IKGX
  • Product descriptionDaphnetin 95%
  • Packaging50mg
  • Price$20
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IKGX
  • Product descriptionDaphnetin 95%
  • Packaging250mg
  • Price$54
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IKGX
  • Product descriptionDaphnetin ≥97%(HPLC)
  • Packaging5g
  • Price$759
  • Updated2026-05-29
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberG-5773
  • Product description7,8-Dihydroxy-2H-benzopyran-2-one 97%
  • Packaging5G
  • Price$820
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberG-5773
  • Product description7,8-Dihydroxy-2H-benzopyran-2-one 97%
  • Packaging1G
  • Price$205
  • Updated2026-05-27
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1622
  • Product descriptionDaphnetin 98%
  • Packaging25g
  • Price$760
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1622
  • Product descriptionDaphnetin 97%
  • Packaging25g
  • Price$760
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0328
  • Product descriptionDaphnetin
  • Packaging5g
  • Price$831
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPXT0015884
  • Product description7,8-DIHYDROXYCOUMARIN 95.00%
  • Packaging500MG
  • Price$912.45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1567
  • Product descriptionDaphnetin
  • Packaging20mg
  • Price$83
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1567
  • Product descriptionDaphnetin
  • Packaging20mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR345097
  • Product description7,8-Dihydroxycoumarin 98%
  • Packaging250mg
  • Price$55
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR345097
  • Product description7,8-Dihydroxycoumarin 98%
  • Packaging100mg
  • Price$32
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR345097
  • Product description7,8-Dihydroxycoumarin 98%
  • Packaging1g
  • Price$210
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR345097
  • Product description7,8-Dihydroxycoumarin 98%
  • Packaging5g
  • Price$928
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00IKGX Daphnetin 95% 100mg $33 2026-05-29 Buy
aablocks AA00IKGX Daphnetin 95% 50mg $20 2026-05-29 Buy
aablocks AA00IKGX Daphnetin 95% 250mg $54 2026-05-29 Buy
aablocks AA00IKGX Daphnetin ≥97%(HPLC) 5g $759 2026-05-29 Buy
ACHEMBLOCK G-5773 7,8-Dihydroxy-2H-benzopyran-2-one 97% 5G $820 2026-05-27 Buy
ACHEMBLOCK G-5773 7,8-Dihydroxy-2H-benzopyran-2-one 97% 1G $205 2026-05-27 Buy
AHH API-1622 Daphnetin 98% 25g $760 2021-12-16 Buy
AHH API-1622 Daphnetin 97% 25g $760 2026-05-26 Buy
AK Scientific V0328 Daphnetin 5g $831 2021-12-16 Buy
American Custom Chemicals Corporation PXT0015884 7,8-DIHYDROXYCOUMARIN 95.00% 500MG $912.45 2021-12-16 Buy
ApexBio Technology N1567 Daphnetin 20mg $83 2026-05-06 Buy
ApexBio Technology N1567 Daphnetin 20mg $100 2021-12-16 Buy
Apolloscientific OR345097 7,8-Dihydroxycoumarin 98% 250mg $55 2026-06-04 Buy
Apolloscientific OR345097 7,8-Dihydroxycoumarin 98% 100mg $32 2026-06-04 Buy
Apolloscientific OR345097 7,8-Dihydroxycoumarin 98% 1g $210 2026-06-04 Buy
Apolloscientific OR345097 7,8-Dihydroxycoumarin 98% 5g $928 2026-06-04 Buy

Properties

Melting point :265-268°C (dec.)
Boiling point :270.35°C (rough estimate)
Density :1.3431 (rough estimate)
refractive index :1.4500 (estimate)
storage temp. :room temp
solubility :soluble in Methanol
form :solid
pka :7.61±0.20(Predicted)
color :White to Light yellow to Light red
biological source :synthetic (organic)
Merck :14,2817
Cosmetics Ingredients Functions :SKIN CONDITIONING
InChI :InChI=1S/C9H6O4/c10-6-3-1-5-2-4-7(11)13-9(5)8(6)12/h1-4,10,12H
InChIKey :ATEFPOUAMCWAQS-UHFFFAOYSA-N
SMILES :C1(=O)OC2=C(O)C(O)=CC=C2C=C1
LogP :0.884 (est)
CAS DataBase Reference :486-35-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Daphnetin is a coumarin analog that acts as an inhibitor of several protein kinases. Inhibits EGFR kinase (IC50 = 7.67 μM), PKA (IC50 = 9.33 μM), and PKC (IC50 = 25 μM), in vitro. The inhibition of EGFR kinase by daphnetin was competitive to ATP and non-competitive to the peptide substrate. Also acts as a potent antioxidant and anti-malarial agent.

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