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ChemicalBook >> CAS DataBase List >> Mitoxantrone hydrochloride

Mitoxantrone hydrochloride

Mitoxantrone hydrochloride price.
  • $8 - $16500
  • Product name: Mitoxantrone hydrochloride
  • CAS: 70476-82-3
  • MF: C22H30Cl2N4O6
  • MW: 517.4028
  • EINECS:274-619-1
  • MDL Number:MFCD00242943
  • Synonyms:Mitoxantrone hydrochloride 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinone dihydrochloride;Mitoxantrone dihydrochloride, >=99%;MITOXANTRONE HYDROCHLORIDE;MITOXANTRONE HYDROCHLORIDE SALT;MITOXANTHRONE HCL;mitozantrone hydrochloride;DHAQ DIHYDROCHLORIDE;1,4-DIHYDROXY-5,8-BIS[2-[(2-HYDROXYETHYL)AMINO]ETHYL]AMINO]-9,10-ANTHRACENEDIONE DIHYDROCHLORIDE
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  • aablocks
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  • Sigma-Aldrich
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  • 60 mg
  • Manufactureraablocks
  • Product numberAA003S22
  • Product description9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, hydrochloride (1:2) 98%
  • Packaging1mg
  • Price$8
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003S22
  • Product description9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, hydrochloride (1:2) ≥97%
  • Packaging10mg
  • Price$10
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003S22
  • Product description9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, hydrochloride (1:2) 98%
  • Packaging50mg
  • Price$31
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003S22
  • Product description9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, hydrochloride (1:2) 98%
  • Packaging100mg
  • Price$42
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003S22
  • Product description9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, hydrochloride (1:2) 98%
  • Packaging250mg
  • Price$59
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberZ238030
  • Product descriptionMitoxantrone dihydrochloride 98%
  • Packaging250MG
  • Price$110
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberZ238030
  • Product descriptionMitoxantrone dihydrochloride 98%
  • Packaging1G
  • Price$270
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberZ238030
  • Product descriptionMitoxantrone dihydrochloride 98%
  • Packaging5G
  • Price$1080
  • Updated2026-05-27
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  • ManufacturerAHH
  • Product numberAPI-1293
  • Product descriptionMitoxantrone hydrochloride 98%
  • Packaging1g
  • Price$610
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberAPI-1293
  • Product descriptionMitoxantrone hydrochloride 97%
  • Packaging1g
  • Price$610
  • Updated2026-05-26
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  • ManufacturerAK Scientific
  • Product numberJ98398
  • Product descriptionMitoxantrone dihydrochloride 97%
  • Packaging1g
  • Price$345
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberH492
  • Product descriptionMitoxantrone Dihydrochloride
  • Packaging500mg
  • Price$375
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberH492
  • Product descriptionMitoxantrone dihydrochloride 98%(HPLC),powder
  • Packaging1g
  • Price$449
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberH492
  • Product descriptionMitoxantrone dihydrochloride 98%(HPLC),powder
  • Packaging500mg
  • Price$237
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ98398
  • Product descriptionMitoxantrone Dihydrochloride
  • Packaging250mg
  • Price$158
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH492
  • Product descriptionMitoxantrone dihydrochloride 98%(HPLC),powder
  • Packaging100mg
  • Price$80
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003S22 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, hydrochloride (1:2) 98% 1mg $8 2026-05-28 Buy
aablocks AA003S22 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, hydrochloride (1:2) ≥97% 10mg $10 2026-05-28 Buy
aablocks AA003S22 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, hydrochloride (1:2) 98% 50mg $31 2026-05-28 Buy
aablocks AA003S22 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, hydrochloride (1:2) 98% 100mg $42 2026-05-28 Buy
aablocks AA003S22 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, hydrochloride (1:2) 98% 250mg $59 2026-05-28 Buy
ACHEMBLOCK Z238030 Mitoxantrone dihydrochloride 98% 250MG $110 2026-05-27 Buy
ACHEMBLOCK Z238030 Mitoxantrone dihydrochloride 98% 1G $270 2026-05-27 Buy
ACHEMBLOCK Z238030 Mitoxantrone dihydrochloride 98% 5G $1080 2026-05-27 Buy
AHH API-1293 Mitoxantrone hydrochloride 98% 1g $610 2021-12-16 Buy
AHH API-1293 Mitoxantrone hydrochloride 97% 1g $610 2026-05-26 Buy
AK Scientific J98398 Mitoxantrone dihydrochloride 97% 1g $345 2026-06-04 Buy
AK Scientific H492 Mitoxantrone Dihydrochloride 500mg $375 2021-12-16 Buy
AK Scientific H492 Mitoxantrone dihydrochloride 98%(HPLC),powder 1g $449 2026-06-04 Buy
AK Scientific H492 Mitoxantrone dihydrochloride 98%(HPLC),powder 500mg $237 2026-06-04 Buy
AK Scientific J98398 Mitoxantrone Dihydrochloride 250mg $158 2021-12-16 Buy
AK Scientific H492 Mitoxantrone dihydrochloride 98%(HPLC),powder 100mg $80 2026-06-04 Buy

Properties

Melting point :203-205 C
storage temp. :2-8°C
solubility :Sparingly soluble in water, slightly soluble in methanol, practically insoluble in acetone.
form :Solid
color :Dark Blue to Black
Water Solubility :Soluble to 5 mM in water and to 75 mM in DMSO
InChI :InChI=1S/C22H28N4O6.2ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;;/h1-4,23-30H,5-12H2;2*1H
InChIKey :ZAHQPTJLOCWVPG-UHFFFAOYSA-N
SMILES :C1(O)=C2C(C(=O)C3=C(C2=O)C(NCCNCCO)=CC=C3NCCNCCO)=C(O)C=C1.[H]Cl.[H]Cl
CAS DataBase Reference :70476-82-3(CAS DataBase Reference)
EPA Substance Registry System :Mitoxantrone hydrochloride (70476-82-3)

Safety Information

Symbol(GHS): Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger
Precautionary statements:
P201 Obtain special instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Mitoxantrone is an anthraquinone that intercalates in DNA and inhibits topoisomerase II (IC50 = 5.3 μM), thus inhibiting cell proliferation. It also inhibits HIV-1 integrase (IC50 = 3.8 μM). Mitoxantrone is exported from cells in an ATP- and glutathione-dependent manner by multidrug resistance protein -1. This compound has found use in various forms of cancer and in multiple sclerosis.

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