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ChemicalBook >> CAS DataBase List >> 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE

4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE

$11 - $2157
Product name: 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
CAS: 757251-39-1
MF: C13H12FN3O2
MW: 261.25
EINECS:692-721-8
MDL Number:MFCD09033852
Synonyms:4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE;2-Pyridinecarboxamide,4-(4-amino-3-fluorophenoxy)-N-methyl-;4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic acid methylamide;4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide;4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYL-2-PYRIDINECARBOXAMIDE;4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide EINECS;4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLIMIDE;Regorafenib Intermediate

Price50 Properties Safety Information Description

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A2B
aablocks
ACHEMBLOCK
AK Scientific
Ambeed
American Custom Chemicals Corporation
Crysdot
Matrix Scientific
Medical Isotopes, Inc.
Oakwood
Sigma-Aldrich
Synthonix
TCI Chemical
TRC

Package

Y0002093
5MG
15mg
200mg
250mg
1g
2.5g
5g
5.00g
10g
10.00g
25g
100g
15 mg

ManufacturerA2B
Product numberAC46511
Product description4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%
Packaging5g
Price$39
Updated2026-05-25
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ManufacturerA2B
Product numberAC46511
Product description4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%
Packaging10g
Price$70
Updated2026-05-25
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ManufacturerA2B
Product numberAC46511
Product description4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%
Packaging25g
Price$148
Updated2026-05-25
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ManufacturerA2B
Product numberAC46511
Product description4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%
Packaging100g
Price$575
Updated2026-05-25
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ManufacturerA2B
Product numberAC46511
Product description4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%
Packaging1g
Price$12
Updated2026-05-25
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Manufactureraablocks
Product numberAA005AAB
Product description4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%
Packaging250mg
Price$14
Updated2026-05-28
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Manufactureraablocks
Product numberAA005AAB
Product description4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 98%
Packaging1g
Price$14
Updated2026-05-28
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Manufactureraablocks
Product numberAA005AAB
Product description4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%
Packaging100g
Price$607
Updated2026-05-28
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Manufactureraablocks
Product numberAA005AAB
Product description4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%
Packaging25g
Price$165
Updated2026-05-28
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Manufactureraablocks
Product numberAA005AAB
Product description4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 98%
Packaging10g
Price$85
Updated2026-05-28
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Manufactureraablocks
Product numberAA005AAB
Product description4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 98%
Packaging5g
Price$47
Updated2026-05-28
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ManufacturerACHEMBLOCK
Product numberW170199
Product description4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide 98%
Packaging100G
Price$360
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberW170199
Product description4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide 98%
Packaging25G
Price$120
Updated2026-05-27
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ManufacturerAK Scientific
Product numberJ90679
Product description4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide
Packaging10g
Price$158
Updated2021-12-16
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ManufacturerAK Scientific
Product numberJ90679
Product description4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide
Packaging1g
Price$43
Updated2021-12-16
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ManufacturerAmbeed
Product numberA353233
Product descriptionRegorafenib impurity A 97%
Packaging5g
Price$60
Updated2026-06-05
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Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
A2B	AC46511	4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%	5g	$39	2026-05-25	Buy
A2B	AC46511	4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%	10g	$70	2026-05-25	Buy
A2B	AC46511	4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%	25g	$148	2026-05-25	Buy
A2B	AC46511	4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%	100g	$575	2026-05-25	Buy
A2B	AC46511	4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%	1g	$12	2026-05-25	Buy
aablocks	AA005AAB	4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%	250mg	$14	2026-05-28	Buy
aablocks	AA005AAB	4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 98%	1g	$14	2026-05-28	Buy
aablocks	AA005AAB	4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%	100g	$607	2026-05-28	Buy
aablocks	AA005AAB	4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 97%	25g	$165	2026-05-28	Buy
aablocks	AA005AAB	4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 98%	10g	$85	2026-05-28	Buy
aablocks	AA005AAB	4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 98%	5g	$47	2026-05-28	Buy
ACHEMBLOCK	W170199	4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide 98%	100G	$360	2026-05-27	Buy
ACHEMBLOCK	W170199	4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide 98%	25G	$120	2026-05-27	Buy
AK Scientific	J90679	4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide	10g	$158	2021-12-16	Buy
AK Scientific	J90679	4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide	1g	$43	2021-12-16	Buy
Ambeed	A353233	Regorafenib impurity A 97%	5g	$60	2026-06-05	Buy

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Properties

Melting point :143 °C
Boiling point :459.8±45.0 °C(Predicted)
Density :1.305
vapor pressure :0Pa at 20℃
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Chloroform (Slightly), DMSO (Sparingly), Methanol (Slightly)
form :Solid
pka :13.92±0.46(Predicted)
color :Orange to Dark Red to Brown
Water Solubility :190mg/L at 20℃
Major Application :pharmaceutical (small molecule)
InChI :InChI=1S/C13H12FN3O2/c1-16-13(18)12-7-9(4-5-17-12)19-8-2-3-11(15)10(14)6-8/h2-7H,15H2,1H3,(H,16,18)
InChIKey :ZQHJPIPGBODVTG-UHFFFAOYSA-N
SMILES :C1(C(NC)=O)=NC=CC(OC2=CC=C(N)C(F)=C2)=C1
LogP :1.3 at 25℃

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning		P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning		P264, P280, P305+P351+P338,P337+P313P

Precautionary statements:

P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P337+P313	IF eye irritation persists: Get medical advice/attention.

Description

4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide is a compound used as a reagent to synthesize Regorafenib (R143000), a multikinase inhibitor that is used to treat patients with advanced colorectal cancer.

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Suppliers and manufacturers

Hubei Lidu New Material Technology Co., Ltd

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide CAS:757251-39-1

career henan chemical co

$2.00
4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE CAS:757251-39-1

Capot Chemical Co.,Ltd.

Beijing Cooperate Pharmaceutical Co.,Ltd

Henan Tianfu Chemical Co.,Ltd.

Nanjing Finetech Chemical Co., Ltd.

ATK CHEMICAL COMPANY LIMITED

Anqing Chico Pharmaceutical Co., Ltd.

Standardpharm Co. Ltd.

Shanghai Longyu Biotechnology Co., Ltd.

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4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE

Properties

Safety Information

Description

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