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ChemicalBook >> CAS DataBase List >> (Trifluoromethyl)trimethylsilane

(Trifluoromethyl)trimethylsilane

(Trifluoromethyl)trimethylsilane price.
  • $10 - $2985.4
  • Product name: (Trifluoromethyl)trimethylsilane
  • CAS: 81290-20-2
  • MF: C4H9F3Si
  • MW: 142.2
  • EINECS:
  • MDL Number:MFCD00145454
  • Synonyms:TriMethyl(trifluoroMethyl)silane solution 0.5 M in THF;(TrifluoroMethyl)triMethylsilane SynonyMs TriMethyl(trifluoroMethyl)silane;(Trimethylsilyl)trifluoromethane Ruppert-Prakash Reagent;Reagents, Ruppert's;TriMethylsilyl(trifluoroMethyl)silane;TriMethyl(trifluoroMethyl)sila;TriMethyl(trifluoroMethyl)silane 99%;TriMethyl(trifluoroMethyl)silane solution ~2.0 M in THF
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  • aablocks
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  • Biosynth
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  • Manufactureraablocks
  • Product numberAA003CMK
  • Product description(Trifluoromethyl)Trimethylsilane ≥96%
  • Packaging5g
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003CMK
  • Product description(Trifluoromethyl)Trimethylsilane ≥96%
  • Packaging25g
  • Price$27
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003CMK
  • Product description(Trifluoromethyl)Trimethylsilane ≥98%
  • Packaging100g
  • Price$101
  • Updated2026-05-28
  • Buy
  • ManufacturerAHH
  • Product numberMT-24207
  • Product description(Trifluoromethyl)trimethylsilane 98%
  • Packaging50g
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-24207
  • Product description(Trifluoromethyl)trimethylsilane 97%
  • Packaging50g
  • Price$230
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-24207
  • Product description(Trifluoromethyl)trimethylsilane 97%
  • Packaging50g
  • Price$230
  • Updated2026-05-26
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC3953
  • Product description(Trifluoromethyl)trimethylsilane,0.5MsolutioninTHF 98%
  • Packaging100ml
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC7779
  • Product description(Trifluoromethyl)trimethylsilane 98%
  • Packaging100g
  • Price$96
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC7779
  • Product description(Trifluoromethyl)trimethylsilane 98%
  • Packaging100g
  • Price$96
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC7779
  • Product description(Trifluoromethyl)trimethylsilane 98%
  • Packaging25g
  • Price$35
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC7779
  • Product description(Trifluoromethyl)trimethylsilane 98%
  • Packaging25g
  • Price$35
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC3953
  • Product description(Trifluoromethyl)trimethylsilane,0.5MsolutioninTHF 98%
  • Packaging25ml
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC7779
  • Product description(Trifluoromethyl)trimethylsilane 98%
  • Packaging5g
  • Price$21
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC7779
  • Product description(Trifluoromethyl)trimethylsilane 98%
  • Packaging5g
  • Price$21
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC3953
  • Product description(Trifluoromethyl)trimethylsilane,0.5MsolutioninTHF 98%
  • Packaging5ml
  • Price$24
  • Updated2021-12-16
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  • ManufacturerBiosynth
  • Product numberGDA29020
  • Product descriptionTrimethyl(trifluoromethyl)silane
  • Packaging0.1kg
  • Price$324.5
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003CMK (Trifluoromethyl)Trimethylsilane ≥96% 5g $10 2026-05-28 Buy
aablocks AA003CMK (Trifluoromethyl)Trimethylsilane ≥96% 25g $27 2026-05-28 Buy
aablocks AA003CMK (Trifluoromethyl)Trimethylsilane ≥98% 100g $101 2026-05-28 Buy
AHH MT-24207 (Trifluoromethyl)trimethylsilane 98% 50g $230 2021-12-16 Buy
AHH MT-24207 (Trifluoromethyl)trimethylsilane 97% 50g $230 2026-05-25 Buy
AHH MT-24207 (Trifluoromethyl)trimethylsilane 97% 50g $230 2026-05-26 Buy
Apolloscientific PC3953 (Trifluoromethyl)trimethylsilane,0.5MsolutioninTHF 98% 100ml $124 2021-12-16 Buy
Apolloscientific PC7779 (Trifluoromethyl)trimethylsilane 98% 100g $96 2026-06-04 Buy
Apolloscientific PC7779 (Trifluoromethyl)trimethylsilane 98% 100g $96 2026-06-04 Buy
Apolloscientific PC7779 (Trifluoromethyl)trimethylsilane 98% 25g $35 2026-06-04 Buy
Apolloscientific PC7779 (Trifluoromethyl)trimethylsilane 98% 25g $35 2026-06-04 Buy
Apolloscientific PC3953 (Trifluoromethyl)trimethylsilane,0.5MsolutioninTHF 98% 25ml $53 2021-12-16 Buy
Apolloscientific PC7779 (Trifluoromethyl)trimethylsilane 98% 5g $21 2026-06-04 Buy
Apolloscientific PC7779 (Trifluoromethyl)trimethylsilane 98% 5g $21 2026-06-04 Buy
Apolloscientific PC3953 (Trifluoromethyl)trimethylsilane,0.5MsolutioninTHF 98% 5ml $24 2021-12-16 Buy
Biosynth GDA29020 Trimethyl(trifluoromethyl)silane 0.1kg $324.5 2026-06-04 Buy

Properties

Boiling point :54-55 °C (lit.)
Density :0.962 g/mL at 20 °C (lit.)
vapor pressure :10.98 psi ( 55 °C)
refractive index :n20/D 1.386
Flash point :14 °F
storage temp. :2-8°C
solubility :sol THF, ether, CH2Cl2.
form :Liquid
Specific Gravity :0.962
color :Clear colorless
Water Solubility :Soluble in alcohol, THF, ether, dichloromethane, aromatic and aliphatic hydrocarbons. Soluble in water(with white smokes).
Sensitive :Moisture Sensitive
Hydrolytic Sensitivity :4: no reaction with water under neutral conditions
Merck :14,9683
BRN :4241868
Exposure limits :ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)
OSHA: TWA 200 ppm(590 mg/m3)
NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3) Stability :Volatile
InChI :1S/C4H9F3Si/c1-8(2,3)4(5,6)7/h1-3H3
InChIKey :MWKJTNBSKNUMFN-UHFFFAOYSA-N
SMILES :C[Si](C)(C)C(F)(F)F
CAS DataBase Reference :81290-20-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): Flame (GHS02)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H261 In contact with water releases flammable gas Substances And Mixtures Which, In Contact With Water,Emit Flammable Gases Category 2
Category 3
Danger
Warning
P231+P232, P280, P370+P378,P402+P404, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P223 Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P231+P232 Handle under inert gas. Protect from moisture.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.

Description

(Trifluoromethyl)trimethylsilane (TMSCF3) is versatile reagent for trifluoromethylation, such as transition-metal-catalyzed reaction, miscellaneous trifluoromethylation, and addition to carbonyl and imine groups. These reactions are extremely useful approaches in the pharmaceutical and agrochemical industry, because they enhance metabolic stability (metabolic blocking) and alter the compound properties (liphophilicity, binding selectivity).

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