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ChemicalBook >> CAS DataBase List >> A 286982

A 286982

$43 - $1800
Product name: A 286982
CAS: 280749-17-9
MF: C24H27N3O4S
MW: 453.55
EINECS:
MDL Number:MFCD19690958
Synonyms:A 286982;(2E)-1-(4-Acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one;2-Propen-1-one, 1-(4-acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-, (2E)-;A 286982,Integrin,allosteric,LFA-1,A286982,Inhibitor,A-286982,inhibit,ICAM-1;A-286982, 10 mM in DMSO

Price50 Properties Safety Information Description

50 prices

Selected condition：

Brand

aablocks
ACHEMBLOCK
AK Scientific
American Custom Chemicals Corporation
ApexBio Technology
Cayman Chemical
ChemScene
DC Chemicals
Sigma-Aldrich
Tocris
TRC
Usbiological

Package

2mg
10mM*1mLinDMSO
1mg
50
5mg
10mg
10
25mg
50mg
100mg
250mg
1g

Manufactureraablocks
Product numberAA00BJOF
Product description(E)-1-(4-Acetylpiperazin-1-yl)-3-(4-((2-isopropylphenyl)thio)-3-nitrophenyl)prop-2-en-1-one
Packaging25mg
Price$198
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00BJOF
Product description(E)-1-(4-Acetylpiperazin-1-yl)-3-(4-((2-isopropylphenyl)thio)-3-nitrophenyl)prop-2-en-1-one
Packaging50mg
Price$316
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00BJOF
Product description(E)-1-(4-Acetylpiperazin-1-yl)-3-(4-((2-isopropylphenyl)thio)-3-nitrophenyl)prop-2-en-1-one
Packaging100mg
Price$460
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00BJOF
Product description(E)-1-(4-Acetylpiperazin-1-yl)-3-(4-((2-isopropylphenyl)thio)-3-nitrophenyl)prop-2-en-1-one
Packaging10mg
Price$108
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00BJOF
Product description(E)-1-(4-Acetylpiperazin-1-yl)-3-(4-((2-isopropylphenyl)thio)-3-nitrophenyl)prop-2-en-1-one ≥98%
Packaging5mg
Price$72
Updated2026-05-28
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Manufactureraablocks
Product numberAA00BJOF
Product description(E)-1-(4-Acetylpiperazin-1-yl)-3-(4-((2-isopropylphenyl)thio)-3-nitrophenyl)prop-2-en-1-one
Packaging2mg
Price$55
Updated2026-05-28
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Manufactureraablocks
Product numberAA00BJOF
Product description(E)-1-(4-Acetylpiperazin-1-yl)-3-(4-((2-isopropylphenyl)thio)-3-nitrophenyl)prop-2-en-1-one
Packaging1mg
Price$44
Updated2026-05-28
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ManufacturerACHEMBLOCK
Product numberU127704
Product descriptionA 286982 98%
Packaging25MG
Price$110
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberU127704
Product descriptionA 286982 98%
Packaging100MG
Price$285
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product numberSYN5060
Product descriptionA-286982
Packaging100mg
Price$940
Updated2021-12-16
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ManufacturerAK Scientific
Product numberSYN5060
Product descriptionA-286982
Packaging10mg
Price$155
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0010263
Product description(2E)-1-(4-ACETYL-1-PIPERAZINYL)-3-[4-[[2-(1-METHYLETHYL)PHENYL]THIO]-3-NITROPHENYL]-2-PROPEN-1-ONE 95.00%
Packaging50MG
Price$1478.35
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0010263
Product description(2E)-1-(4-ACETYL-1-PIPERAZINYL)-3-[4-[[2-(1-METHYLETHYL)PHENYL]THIO]-3-NITROPHENYL]-2-PROPEN-1-ONE 95.00%
Packaging10MG
Price$806.48
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA8664
Product descriptionA 286982
Packaging50mg
Price$610
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberA8664
Product descriptionA286982
Packaging50mg
Price$1385
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA8664
Product descriptionA286982
Packaging10mg
Price$339
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00BJOF	(E)-1-(4-Acetylpiperazin-1-yl)-3-(4-((2-isopropylphenyl)thio)-3-nitrophenyl)prop-2-en-1-one	25mg	$198	2026-05-28	Buy
aablocks	AA00BJOF	(E)-1-(4-Acetylpiperazin-1-yl)-3-(4-((2-isopropylphenyl)thio)-3-nitrophenyl)prop-2-en-1-one	50mg	$316	2026-05-28	Buy
aablocks	AA00BJOF	(E)-1-(4-Acetylpiperazin-1-yl)-3-(4-((2-isopropylphenyl)thio)-3-nitrophenyl)prop-2-en-1-one	100mg	$460	2026-05-28	Buy
aablocks	AA00BJOF	(E)-1-(4-Acetylpiperazin-1-yl)-3-(4-((2-isopropylphenyl)thio)-3-nitrophenyl)prop-2-en-1-one	10mg	$108	2026-05-28	Buy
aablocks	AA00BJOF	(E)-1-(4-Acetylpiperazin-1-yl)-3-(4-((2-isopropylphenyl)thio)-3-nitrophenyl)prop-2-en-1-one ≥98%	5mg	$72	2026-05-28	Buy
aablocks	AA00BJOF	(E)-1-(4-Acetylpiperazin-1-yl)-3-(4-((2-isopropylphenyl)thio)-3-nitrophenyl)prop-2-en-1-one	2mg	$55	2026-05-28	Buy
aablocks	AA00BJOF	(E)-1-(4-Acetylpiperazin-1-yl)-3-(4-((2-isopropylphenyl)thio)-3-nitrophenyl)prop-2-en-1-one	1mg	$44	2026-05-28	Buy
ACHEMBLOCK	U127704	A 286982 98%	25MG	$110	2026-05-27	Buy
ACHEMBLOCK	U127704	A 286982 98%	100MG	$285	2026-05-27	Buy
AK Scientific	SYN5060	A-286982	100mg	$940	2021-12-16	Buy
AK Scientific	SYN5060	A-286982	10mg	$155	2021-12-16	Buy
American Custom Chemicals Corporation	API0010263	(2E)-1-(4-ACETYL-1-PIPERAZINYL)-3-[4-[[2-(1-METHYLETHYL)PHENYL]THIO]-3-NITROPHENYL]-2-PROPEN-1-ONE 95.00%	50MG	$1478.35	2021-12-16	Buy
American Custom Chemicals Corporation	API0010263	(2E)-1-(4-ACETYL-1-PIPERAZINYL)-3-[4-[[2-(1-METHYLETHYL)PHENYL]THIO]-3-NITROPHENYL]-2-PROPEN-1-ONE 95.00%	10MG	$806.48	2021-12-16	Buy
ApexBio Technology	A8664	A 286982	50mg	$610	2026-05-06	Buy
ApexBio Technology	A8664	A286982	50mg	$1385	2021-12-16	Buy
ApexBio Technology	A8664	A286982	10mg	$339	2021-12-16	Buy

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Properties

storage temp. :-20°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
color :white to beige
InChI :1S/C24H27N3O4S/c1-17(2)20-6-4-5-7-22(20)32-23-10-8-19(16-21(23)27(30)31)9-11-24(29)26-14-12-25(13-15-26)18(3)28/h4-11,16-17H,12-15H2,1-3H3/b11-9+
InChIKey :HTGGAYLWTDOFDK-PKNBQFBNSA-N
SMILES :S(c2c(cc(cc2)\C=C\C(=O)N3CCN(CC3)C(=O)C)[N+](=O)[O-])c1c(cccc1)C(C)C

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330	Rinse mouth.
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P337+P313	IF eye irritation persists: Get medical advice/attention.
P362	Take off contaminated clothing and wash before reuse.
P403+P233	Store in a well-ventilated place. Keep container tightly closed.
P405	Store locked up.
P501	Dispose of contents/container to..…

Description

A286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1; IC₅₀ = 35 nM). It inhibits adhesion of JY-8 cells to ICAM-1-coated microtiter plates (IC₅₀ = 44 nM).

Suppliers and manufacturers

TargetMol Chemicals Inc.

$68.00
A-286982 CAS:280749-17-9

Career Henan Chemica Co

BOC Sciences

InvivoChem

Hangzhou MolCore BioPharmatech Co.,Ltd.

Wuhan Topule Biopharmaceutical Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd

Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd

Aladdin Scientific

Wuhan Jingkang en Biomedical Technology Co., Ltd

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A 286982

Properties

Safety Information

Description

Suppliers and manufacturers