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ChemicalBook >> CAS DataBase List >> AKTI-1/2

AKTI-1/2

$29 - $2200
Product name: AKTI-1/2
CAS: 612847-09-3
MF: C34H29N7O
MW: 551.64
EINECS:1592732-453-0
MDL Number:MFCD09026909
Synonyms:1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-on;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-γ],guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one;2H-BenziMidazol-2-one, 1,3-dihydro-1-[1-[[4-(6-phenyl-1H-iMidazo[4,5-g]quinoxalin-7-yl)phenyl]Methyl]-4-piperidinyl]-;AKT inhibitor VIII (AKTI-1/2);1-(1-(4-(6-Phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl)-piperidin-4-yl)-1H-benzo[d]imidazol-2(;1-(1-(4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one

Price83 Properties Safety Information Description

83 prices

Selected condition：

Brand

aablocks
ACHEMBLOCK
AK Scientific
American Custom Chemicals Corporation
ApexBio Technology
Axon Medchem
Biosynth
Cayman Chemical
Chem-Impex
ChemScene
Crysdot
DC Chemicals
Matrix Scientific
Medical Isotopes, Inc.
Sigma-Aldrich
TCI Chemical
TRC
Usbiological

Package

10mM(in1mLDMSO)
2.5MG
500μg
10mM(in 1mL DMSO)
10mM*1mLinDMSO
1mg
2mg
5mg
10mg
25mg
50mg
100mg
250mg
1g

Manufactureraablocks
Product numberAA00EC9W
Product descriptionAKT inhibitor VIII ≥98%
Packaging1mg
Price$61
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00EC9W
Product descriptionAKT inhibitor VIII
Packaging2mg
Price$69
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00EC9W
Product descriptionAKT inhibitor VIII ≥97%
Packaging5mg
Price$90
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00EC9W
Product descriptionAKT inhibitor VIII
Packaging10mg
Price$144
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00EC9W
Product descriptionAKT inhibitor VIII
Packaging100mg
Price$476
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00EC9W
Product descriptionAKT inhibitor VIII
Packaging50mg
Price$338
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00EC9W
Product descriptionAKT inhibitor VIII
Packaging25mg
Price$243
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberY230492
Product descriptionAKT Inhibitor VIII 98%
Packaging10MG
Price$185
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberY230492
Product descriptionAKT Inhibitor VIII 98%
Packaging25MG
Price$330
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberY230492
Product descriptionAKT Inhibitor VIII 98%
Packaging100MG
Price$680
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product numberX2144
Product descriptionAKT Inhibitor VIII
Packaging250mg
Price$1454
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberINB0000362
Product descriptionAKTI-1/2 INHIBITOR 95.00%
Packaging25MG
Price$1963.5
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberINB0000362
Product descriptionAKTI-1/2 INHIBITOR 95.00%
Packaging2.5MG
Price$715
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberINB0000362
Product descriptionAKTI-1/2 INHIBITOR 95.00%
Packaging1MG
Price$240.45
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA3149
Product descriptionAKT Inhibitor VIII
Packaging10mg
Price$145
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA3149
Product descriptionAKT Inhibitor VIII
Packaging10mM(in 1mL DMSO)
Price$130
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00EC9W	AKT inhibitor VIII ≥98%	1mg	$61	2026-05-28	Buy
aablocks	AA00EC9W	AKT inhibitor VIII	2mg	$69	2026-05-28	Buy
aablocks	AA00EC9W	AKT inhibitor VIII ≥97%	5mg	$90	2026-05-28	Buy
aablocks	AA00EC9W	AKT inhibitor VIII	10mg	$144	2026-05-28	Buy
aablocks	AA00EC9W	AKT inhibitor VIII	100mg	$476	2026-05-28	Buy
aablocks	AA00EC9W	AKT inhibitor VIII	50mg	$338	2026-05-28	Buy
aablocks	AA00EC9W	AKT inhibitor VIII	25mg	$243	2026-05-28	Buy
ACHEMBLOCK	Y230492	AKT Inhibitor VIII 98%	10MG	$185	2026-05-27	Buy
ACHEMBLOCK	Y230492	AKT Inhibitor VIII 98%	25MG	$330	2026-05-27	Buy
ACHEMBLOCK	Y230492	AKT Inhibitor VIII 98%	100MG	$680	2026-05-27	Buy
AK Scientific	X2144	AKT Inhibitor VIII	250mg	$1454	2021-12-16	Buy
American Custom Chemicals Corporation	INB0000362	AKTI-1/2 INHIBITOR 95.00%	25MG	$1963.5	2021-12-16	Buy
American Custom Chemicals Corporation	INB0000362	AKTI-1/2 INHIBITOR 95.00%	2.5MG	$715	2021-12-16	Buy
American Custom Chemicals Corporation	INB0000362	AKTI-1/2 INHIBITOR 95.00%	1MG	$240.45	2021-12-16	Buy
ApexBio Technology	A3149	AKT Inhibitor VIII	10mg	$145	2021-12-16	Buy
ApexBio Technology	A3149	AKT Inhibitor VIII	10mM(in 1mL DMSO)	$130	2021-12-16	Buy

Next Last

Properties

Melting point :242-245°C (dec.)
Density :1.350±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL in DMSO
form :Yellow solid
pka :7.49±0.50(Predicted)
color :White to Yellow to Orange
InChIKey :BIWGYFZAEWGBAL-UHFFFAOYSA-N
SMILES :N6(CCC(CC6)[n]7c8c(nc7O)cccc8)Cc1ccc(cc1)c2nc3c(nc2c5ccccc5)cc4[nH]cnc4c3
CAS DataBase Reference :612847-09-3

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKBα, β, γ) modulate cell proliferation, metabolism, and survival as well as angiogenesis. Akt inhibitor VIII is a potent allosteric inhibitor of Akt1 and Akt2 (IC50s = 58 and 210 nM, respectively) that less effectively blocks Akt3 activity (IC50 = 2.2 μM). It is a poor or ineffective inhibitor of a wide range of other serine-threonine kinases. Akt inhibitor VIII is cell permeable, blocking insulin regulation of forkhead box 01 activity at 1 μM in rat hepatoma cells.

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Suppliers and manufacturers

career henan chemical co

$2.00
AKTI-1/2 CAS:612847-09-3

TargetMol Chemicals Inc.

$61.00
AKT inhibitor VIII CAS:612847-09-3

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Jinan Carbotang Biotech Co.,Ltd.

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BOC Sciences

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AKTI-1/2

Properties

Safety Information

Description

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