Alsterpaullone
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- $20 - $3219
- Product name: Alsterpaullone
- CAS: 237430-03-4
- MF: C16H11N3O3
- MW: 293.28
- EINECS:
- MDL Number:MFCD02683579
- Synonyms:ALSTERPAULLONE;9-NITRO-7,12-DIHYDROINDOLO-[3,2-D][1]BENZAZEPIN-6(5H)-ONE;9-NITRO-7,12-DIHYDROINDOLO-[3,2-D][1]BENZAZEPIN-6(5)-ONE;9-nitro-7,12-dihydrobenzo[2,3]azepino[4,5-b]indol-6(5H)-one;9-Nitropaullone;Alsterpaullone (9-Nitropaullone;ALSTERPAULLONE (9-NITROPAULLONE;NSC 705701);Alsteropaullone
61 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO(Solid+Solvent)
- 2.5mg
- 1mg
- 10
- 10mM*1mLinDMSO
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 1G
- Manufactureraablocks
- Product numberAA00BC3C
- Product descriptionAlsterpaullone 98%
- Packaging1mg
- Price$20
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BC3C
- Product descriptionAlsterpaullone 98%
- Packaging5mg
- Price$45
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BC3C
- Product descriptionAlsterpaullone ≥98%
- Packaging25mg
- Price$143
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BC3C
- Product descriptionAlsterpaullone ≥98%
- Packaging50mg
- Price$241
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BC3C
- Product descriptionAlsterpaullone ≥98%
- Packaging100mg
- Price$407
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203411
- Product descriptionAlsterpaullone 98.00%
- Packaging100MG
- Price$395
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203411
- Product descriptionAlsterpaullone 98.00%
- Packaging250MG
- Price$815
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203411
- Product descriptionAlsterpaullone 98.00%
- Packaging1G
- Price$2445
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0036-M005
- Product descriptionAlsterpaullone ≥98%(NMR)
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0036-M005
- Product descriptionAlsterpaullone ≥98%(NMR)
- Packaging5mg
- Price$200
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0036-M001
- Product descriptionAlsterpaullone ≥98%(NMR)
- Packaging1mg
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product number2336BB
- Product descriptionAlsterpaullone
- Packaging1mg
- Price$174
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2336BB
- Product descriptionAlsterpaullone
- Packaging5mg
- Price$434
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA310955
- Product description7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one 98%
- Packaging250mg
- Price$1347
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA310955
- Product description7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one 98%
- Packaging1g
- Price$3219
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA310955
- Product description7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one 98%
- Packaging5mg
- Price$296
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00BC3C | Alsterpaullone 98% | 1mg | $20 | 2026-05-28 | Buy |
| aablocks | AA00BC3C | Alsterpaullone 98% | 5mg | $45 | 2026-05-28 | Buy |
| aablocks | AA00BC3C | Alsterpaullone ≥98% | 25mg | $143 | 2026-05-28 | Buy |
| aablocks | AA00BC3C | Alsterpaullone ≥98% | 50mg | $241 | 2026-05-28 | Buy |
| aablocks | AA00BC3C | Alsterpaullone ≥98% | 100mg | $407 | 2026-05-28 | Buy |
| ACHEMBLOCK | X203411 | Alsterpaullone 98.00% | 100MG | $395 | 2026-05-27 | Buy |
| ACHEMBLOCK | X203411 | Alsterpaullone 98.00% | 250MG | $815 | 2026-05-27 | Buy |
| ACHEMBLOCK | X203411 | Alsterpaullone 98.00% | 1G | $2445 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CR1-0036-M005 | Alsterpaullone ≥98%(NMR) | 5mg | $120 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-0036-M005 | Alsterpaullone ≥98%(NMR) | 5mg | $200 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-0036-M001 | Alsterpaullone ≥98%(NMR) | 1mg | $50 | 2026-05-06 | Buy |
| AK Scientific | 2336BB | Alsterpaullone | 1mg | $174 | 2021-12-16 | Buy |
| AK Scientific | 2336BB | Alsterpaullone | 5mg | $434 | 2021-12-16 | Buy |
| Ambeed | A310955 | 7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one 98% | 250mg | $1347 | 2021-12-16 | Buy |
| Ambeed | A310955 | 7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one 98% | 1g | $3219 | 2021-12-16 | Buy |
| Ambeed | A310955 | 7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one 98% | 5mg | $296 | 2021-12-16 | Buy |
Properties
Melting point :>330℃
Boiling point :651.5±45.0 °C(Predicted)
Density :1.461±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble
form :powder
pka :14.18±0.20(Predicted)
color :brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :1S/C16H11N3O3/c20-15-8-12-11-7-9(19(21)22)5-6-14(11)18-16(12)10-3-1-2-4-13(10)17-15/h1-7,18H,8H2,(H,17,20)
InChIKey :OLUKILHGKRVDCT-UHFFFAOYSA-N
SMILES :[O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1
Boiling point :651.5±45.0 °C(Predicted)
Density :1.461±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble
form :powder
pka :14.18±0.20(Predicted)
color :brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI :1S/C16H11N3O3/c20-15-8-12-11-7-9(19(21)22)5-6-14(11)18-16(12)10-3-1-2-4-13(10)17-15/h1-7,18H,8H2,(H,17,20)
InChIKey :OLUKILHGKRVDCT-UHFFFAOYSA-N
SMILES :[O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Alsterpaullone is a derivative of kenpaullone , an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3β (GSK3β). With slightly improved potency over kenpaullone, alsterpaullone selectively inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and GSK3α/β with IC50 values of 35, 15, 200, 40, and 4 nM, respectively. Alsterpaullone has been used to inhibit the cytosolic degradation of β-catenin to alter the canonical Wnt signaling pathway in primary axis patterning, to reduce tau phosphorylation in an effort to modify neuropathological events associated with Alzheimer’s disease, and to alter cell proliferation or protein expression in various diseases.More related product prices
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