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ChemicalBook >> CAS DataBase List >> API-2

API-2

$46 - $3870
Product name: API-2
CAS: 35943-35-2
MF: C13H16N6O4
MW: 320.3
EINECS:
MDL Number:MFCD00932413
Synonyms:API-2;6-AMINO-4-METHYL-8-(BETA-D-RIBOFURANOSYL)-4H,8H-PYRROLO[4,3,2-DE]PYRIMIDO[4,5-C]PYRIDAZINE;AKT/PKB SIGNALING INHIBITOR-2;1,5-DIHYDRO-5-METHYL-1-BETA-D-RIBOFURANOSYL-1,4,5,6,8-PENTAAZAACENAPHTHYLEN-3-AMINE;1,4,5,6,8-pentaazaacenaphthylen-3-amine,1,5-dihydro-5-methyl-1-beta-d-ribofura ;API-2 (Tricirbine);NSC 154020;TCN

Price102 Properties Safety Information Description

102 prices

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Brand

aablocks
ACHEMBLOCK
AHH
American Custom Chemicals Corporation
ApexBio Technology
Arctom
Biorbyt Ltd
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
CSNpharm
DC Chemicals
Sigma-Aldrich
Tocris
TRC
Usbiological

Package

10μg
250mg
100 μL
400μL
10mM*1mLinDMSO(Solution)
50ug
1mg
100ul
200ul
10
10mM*1mLinDMSO(Solid+Solvent)
100ug
2mg
5mg
10mg
0.01g
25mg
50mg
100mg
200mg
1G

Manufactureraablocks
Product numberAA00C08V
Product description1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-
Packaging1mg
Price$46
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00C08V
Product description1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-
Packaging2mg
Price$56
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00C08V
Product description1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-
Packaging5mg
Price$79
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00C08V
Product description1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-
Packaging10mg
Price$115
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00C08V
Product description1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-
Packaging25mg
Price$195
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00C08V
Product description1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-
Packaging50mg
Price$298
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00C08V
Product description1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-
Packaging100mg
Price$451
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00C08V
Product description1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-
Packaging200mg
Price$633
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product number10760
Product descriptionAPI-2 98%
Packaging100MG
Price$645
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product number10760
Product descriptionAPI-2 98%
Packaging1G
Price$3870
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product number10760
Product descriptionAPI-2 98%
Packaging25MG
Price$260
Updated2026-05-27
Buy

ManufacturerAHH
Product numberMT-09744
Product description1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8pentaazaacenaphthylen-3-amine 98%
Packaging0.01g
Price$415
Updated2021-12-16
Buy

ManufacturerAHH
Product numberMT-09744
Product description1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8pentaazaacenaphthylen-3-amine 97%
Packaging0.01g
Price$415
Updated2026-05-25
Buy

ManufacturerAHH
Product numberMT-09744
Product description1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8pentaazaacenaphthylen-3-amine 97%
Packaging0.01g
Price$415
Updated2026-05-26
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0001275
Product descriptionTRICIRIBINE HYDRATE 95.00%
Packaging5MG
Price$773.74
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0001275
Product descriptionTRICIRIBINE HYDRATE 95.00%
Packaging25MG
Price$1343.73
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00C08V	1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-	1mg	$46	2026-05-28	Buy
aablocks	AA00C08V	1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-	2mg	$56	2026-05-28	Buy
aablocks	AA00C08V	1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-	5mg	$79	2026-05-28	Buy
aablocks	AA00C08V	1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-	10mg	$115	2026-05-28	Buy
aablocks	AA00C08V	1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-	25mg	$195	2026-05-28	Buy
aablocks	AA00C08V	1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-	50mg	$298	2026-05-28	Buy
aablocks	AA00C08V	1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-	100mg	$451	2026-05-28	Buy
aablocks	AA00C08V	1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-β-D-ribofuranosyl-	200mg	$633	2026-05-28	Buy
ACHEMBLOCK	10760	API-2 98%	100MG	$645	2026-05-27	Buy
ACHEMBLOCK	10760	API-2 98%	1G	$3870	2026-05-27	Buy
ACHEMBLOCK	10760	API-2 98%	25MG	$260	2026-05-27	Buy
AHH	MT-09744	1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8pentaazaacenaphthylen-3-amine 98%	0.01g	$415	2021-12-16	Buy
AHH	MT-09744	1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8pentaazaacenaphthylen-3-amine 97%	0.01g	$415	2026-05-25	Buy
AHH	MT-09744	1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8pentaazaacenaphthylen-3-amine 97%	0.01g	$415	2026-05-26	Buy
American Custom Chemicals Corporation	KIN0001275	TRICIRIBINE HYDRATE 95.00%	5MG	$773.74	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0001275	TRICIRIBINE HYDRATE 95.00%	25MG	$1343.73	2021-12-16	Buy

Next Last

Properties

Melting point :207 °C (decomp)
Boiling point :459.21°C (rough estimate)
Density :1.2633 (rough estimate)
refractive index :1.7000 (estimate)
storage temp. :Store at RT
solubility :DMSO: >10mg/mL
form :powder
pka :12.35±0.70(Predicted)
color :tan
biological source :rabbit
InChI :InChI=1/C13H16N6O4/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17)/t6-,8-,9-,13-/s3
InChIKey :HOGVTUZUJGHKPL-HTVVRFAVSA-N
SMILES :C12C3=NC=NC=1N(C=C2C(N)=NN3C)[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 |&1:14,15,17,19,r|

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H317	May cause an allergic skin reaction	Sensitisation, Skin	Category 1	Warning		P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning		P264, P280, P305+P351+P338,P337+P313P

Precautionary statements:

P280	Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Triciribine, also known as API-2, suppresses the phosphorylation level and kinase activity of Akt. Akt kinase inhibition has been shown to induce apoptosis and cell growth in cancer cell research. Triciribine can selectively inhibit Akt1, Akt2, and Akt3 without inhibiting known upstream activators,PDK1 and PI 3-Kinase, of Akt. Studies show that Triciribine in duces apoptosis and inhibits cell growth in cells that express atypical Akt1. Additionally, Triciribine has antineoplastic and antiviral activity at low micromolar and submicromolar concentrations, and has been demonstrated to inhibit incorporation of amino acids into proteins and purine nucleotide synthesis.

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Suppliers and manufacturers

career henan chemical co

$2.00
API-2 CAS:35943-35-2

TargetMol Chemicals Inc.

$32.00
Triciribine CAS:35943-35-2

Wuhan Nutra Biotechnology Co.,Ltd

Triciribine hydrate;TCN CAS:35943-35-2

Biochempartner

Zhengzhou Alfa Chemical Co.,Ltd

Dideu Industries Group Limited

BOC Sciences

Dayang Chem (Hangzhou) Co.,Ltd.

Zhejiang J&C Biological Technology Co.,Limited

NewCan Biotech Limited

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API-2

Properties

Safety Information

Description

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