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ChemicalBook >> CAS DataBase List >> Acyclovir

Acyclovir

Acyclovir price.
  • $5 - $1140
  • Product name: Acyclovir
  • CAS: 59277-89-3
  • MF: C8H11N5O3
  • MW: 225.2
  • EINECS:261-685-1
  • MDL Number:MFCD00057880
  • Synonyms:1,9-dihydro-2-amino-9-((2-hydroxyethoxy)methyl)-6h-purin-6-on ;2-amino-1,9-dihydro-9-((2-hydroxyethoxy)-methyl)-6h-purin-6-on ;aciclovirum(latin) ;acielovir;cycloguanosine;Zoviax;2-amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-6h-purin-6-one;ACYCLOVIR SUBST
135 prices
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Brand
  • aablocks
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Aronis compounds
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  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chem-Impex
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  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • SynQuest Laboratories
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  • Usbiological
Package
  • 25mg
  • a0220000
  • 20mg
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  • 2x50mg
  • 250mg
  • 300mg
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  • 1g
  • 5.00g
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  • 25g
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  • 50
  • 50g
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  • 10mM(in 1mL DMSO)
  • 1kg
  • 10mM(in1mLDMSO)
  • 1000.00g
  • 1000g
  • 0.3 mg
  • 2 μg
  • 20 mg
  • 75 mg
  • 100 mg
  • Manufactureraablocks
  • Product numberAA0034C8
  • Product description9-[(2-Hydroxyethoxy)Methyl]Guanine 98%
  • Packaging50mg
  • Price$8
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0034C8
  • Product description9-[(2-Hydroxyethoxy)Methyl]Guanine ≥95%
  • Packaging25g
  • Price$15
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0034C8
  • Product description9-[(2-Hydroxyethoxy)Methyl]Guanine 98%
  • Packaging5g
  • Price$9
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0034C8
  • Product description9-[(2-Hydroxyethoxy)Methyl]Guanine 98%
  • Packaging100g
  • Price$40
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0034C8
  • Product description9-[(2-Hydroxyethoxy)Methyl]Guanine 98%
  • Packaging1kg
  • Price$352
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product numberF872
  • Product descriptionAcycloguanosine 98%(HPLC)
  • Packaging500g
  • Price$302
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberF872
  • Product descriptionAcycloguanosine
  • Packaging500g
  • Price$319
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberF872
  • Product descriptionAcycloguanosine 98%(HPLC)
  • Packaging25g
  • Price$40
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberF872
  • Product descriptionAcycloguanosine
  • Packaging25g
  • Price$37
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ95702
  • Product descriptionAcycloguanosine 95%
  • Packaging25g
  • Price$29
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ95702
  • Product descriptionAcycloguanosine 95%
  • Packaging1g
  • Price$12
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ10243
  • Product descriptionAcycloguanosine 99%(HPLC),powder
  • Packaging25mg
  • Price$22
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberF872
  • Product descriptionAcycloguanosine 98%(HPLC)
  • Packaging1g
  • Price$16
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ95702
  • Product descriptionAcycloguanosine 95%
  • Packaging5g
  • Price$17
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberF872
  • Product descriptionAcycloguanosine 98%(HPLC)
  • Packaging5g
  • Price$18
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10243
  • Product descriptionAcycloguanosine 99%(HPLC),powder
  • Packaging100mg
  • Price$63
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0034C8 9-[(2-Hydroxyethoxy)Methyl]Guanine 98% 50mg $8 2026-05-28 Buy
aablocks AA0034C8 9-[(2-Hydroxyethoxy)Methyl]Guanine ≥95% 25g $15 2026-05-28 Buy
aablocks AA0034C8 9-[(2-Hydroxyethoxy)Methyl]Guanine 98% 5g $9 2026-05-28 Buy
aablocks AA0034C8 9-[(2-Hydroxyethoxy)Methyl]Guanine 98% 100g $40 2026-05-28 Buy
aablocks AA0034C8 9-[(2-Hydroxyethoxy)Methyl]Guanine 98% 1kg $352 2026-05-28 Buy
AK Scientific F872 Acycloguanosine 98%(HPLC) 500g $302 2026-06-04 Buy
AK Scientific F872 Acycloguanosine 500g $319 2021-12-16 Buy
AK Scientific F872 Acycloguanosine 98%(HPLC) 25g $40 2026-06-04 Buy
AK Scientific F872 Acycloguanosine 25g $37 2021-12-16 Buy
AK Scientific J95702 Acycloguanosine 95% 25g $29 2026-06-04 Buy
AK Scientific J95702 Acycloguanosine 95% 1g $12 2026-06-04 Buy
AK Scientific J10243 Acycloguanosine 99%(HPLC),powder 25mg $22 2026-06-04 Buy
AK Scientific F872 Acycloguanosine 98%(HPLC) 1g $16 2026-06-04 Buy
AK Scientific J95702 Acycloguanosine 95% 5g $17 2026-06-04 Buy
AK Scientific F872 Acycloguanosine 98%(HPLC) 5g $18 2026-06-04 Buy
AK Scientific J10243 Acycloguanosine 99%(HPLC),powder 100mg $63 2026-06-04 Buy

Properties

Melting point :256-257°C
Boiling point :366.71°C (rough estimate)
Density :1.3654 (rough estimate)
refractive index :1.8000 (estimate)
storage temp. :2-8°C
solubility :H2O: 0.7 mg/mL
form :powder
pka :pKa 2.27 (Uncertain);9.25 (Uncertain)
color :white
Water Solubility :Soluble in 1M HCl at 50mg/ml. Soluble in water at 0.7mg/ml. Also soluble in DMSO
ε(extinction coefficient) :11.8 at 256nm at 1mM
Merck :14,146
Henry's Law Constant :3.1×1016 mol/(m3Pa) at 25℃, HSDB (2015)
BCS Class :4,3
Stability :Stable. Incompatible with strong oxidizing agents.
InChI :1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)
InChIKey :MKUXAQIIEYXACX-UHFFFAOYSA-N
SMILES :NC1=Nc2c(ncn2COCCO)C(=O)N1
LogP :-0.617 (est)
CAS DataBase Reference :59277-89-3(CAS DataBase Reference)
IARC :3 (Vol. 76) 2000

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.

Description

Acyclovir is a guanosine analog with antiviral activity in vitro against the herpes simplex viruses, varicella zoster virus, Epstein-Barr virus, cytomegalovirus, and human herpes virus 6 (ID50s = 0.1 - 63.1 μM). Acyclovir differs from most nucleoside analogs in that it contains only a partial nucleoside structure with an acyclic side chain. It diffuses freely into cells and is selectively converted into acyclo-guanosine monophosphate by a virus-specific thymidine kinase. During DNA replication, the phosphorylated form of acyclovir is preferentially incorporated into viral DNA, resulting in premature chain termination and inhibition of further activity of DNA polymerase.

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