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ChemicalBook >> CAS DataBase List >> Amlodipine

Amlodipine

Amlodipine price.
  • $5 - $2541
  • Product name: Amlodipine
  • CAS: 88150-42-9
  • MF: C20H25ClN2O5
  • MW: 408.88
  • EINECS:1308068-626-2
  • MDL Number:MFCD00864687
  • Synonyms:AMLODIPINE MM(CRM STANDARD);Amlodipine∬AmlodipineBesylate/Maleate;3,5-Pyridinedicarboxylic acid, 2-(2-aminoethoxy)methyl-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester;ethyl methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate;Pelmec;Racemic Amlodipine;3,5-pyridinedicarboxylic acid, 1,4-dihydro-2-((2-aminoethoxy)methyl)-4-(2-chlor 3-ethyl 5-methyl ester
71 prices
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  • aablocks
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  • TCI Chemical
  • Thermo Scientific Chemicals
  • TRC
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Package
  • 1unit
  • 10mM(in1mLDMSO)
  • 10mM(in 1mL DMSO)
  • EvaluationSample
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  • Manufactureraablocks
  • Product numberAA00IEWU
  • Product description3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester ≥98%
  • Packaging1g
  • Price$10
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IEWU
  • Product description3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester 99%
  • Packaging5g
  • Price$16
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IEWU
  • Product description3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester 99%
  • Packaging10g
  • Price$19
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IEWU
  • Product description3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester 99%
  • Packaging25g
  • Price$30
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IEWU
  • Product description3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester 99%
  • Packaging100g
  • Price$95
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00IEWU
  • Product description3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester 95%
  • Packaging500g
  • Price$385
  • Updated2026-05-29
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  • ManufacturerAbosyn
  • Product number61-11487
  • Product descriptionAmlodipine 95-98%
  • Packaging5g
  • Price$405
  • Updated2021-12-16
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  • ManufacturerAbosyn
  • Product number61-11487
  • Product descriptionAmlodipine 95-98%
  • Packaging1g
  • Price$65
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberK577
  • Product descriptionAmlodipine 98%(HPLC)
  • Packaging1g
  • Price$37
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ10237
  • Product descriptionAmlodipine 99%(HPLC),powder
  • Packaging100mg
  • Price$28
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ99276
  • Product descriptionAmlodipine 95%
  • Packaging25g
  • Price$28
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ99276
  • Product descriptionAmlodipine 95%
  • Packaging5g
  • Price$12
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10237
  • Product descriptionAmlodipine 99%(HPLC),powder
  • Packaging1g
  • Price$68
  • Updated2026-06-04
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  • ManufacturerAmbeed
  • Product numberA367713
  • Product description3-Ethyl5-methyl2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate 99+%
  • Packaging25g
  • Price$41
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA367713
  • Product description3-Ethyl5-methyl2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate 99+%
  • Packaging10g
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA367713
  • Product description3-Ethyl5-methyl2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate 99+%
  • Packaging5g
  • Price$11
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00IEWU 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester ≥98% 1g $10 2026-05-29 Buy
aablocks AA00IEWU 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester 99% 5g $16 2026-05-29 Buy
aablocks AA00IEWU 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester 99% 10g $19 2026-05-29 Buy
aablocks AA00IEWU 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester 99% 25g $30 2026-05-29 Buy
aablocks AA00IEWU 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester 99% 100g $95 2026-05-29 Buy
aablocks AA00IEWU 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester 95% 500g $385 2026-05-29 Buy
Abosyn 61-11487 Amlodipine 95-98% 5g $405 2021-12-16 Buy
Abosyn 61-11487 Amlodipine 95-98% 1g $65 2021-12-16 Buy
AK Scientific K577 Amlodipine 98%(HPLC) 1g $37 2026-06-04 Buy
AK Scientific J10237 Amlodipine 99%(HPLC),powder 100mg $28 2026-06-04 Buy
AK Scientific J99276 Amlodipine 95% 25g $28 2026-06-04 Buy
AK Scientific J99276 Amlodipine 95% 5g $12 2026-06-04 Buy
AK Scientific J10237 Amlodipine 99%(HPLC),powder 1g $68 2026-06-04 Buy
Ambeed A367713 3-Ethyl5-methyl2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate 99+% 25g $41 2021-12-16 Buy
Ambeed A367713 3-Ethyl5-methyl2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate 99+% 10g $20 2021-12-16 Buy
Ambeed A367713 3-Ethyl5-methyl2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate 99+% 5g $11 2021-12-16 Buy

Properties

Melting point :178-179°C
Boiling point :527.2±50.0 °C(Predicted)
Density :1.227±0.06 g/cm3(Predicted)
RTECS :US7968329
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 25 mg/ml), in DMF (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
pka :pKa 8.6 (Uncertain)
form :Almost white crystal powder
color :White
Water Solubility :75.3 mg/L
BCS Class :1
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF, or ethanol may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3
InChIKey :HTIQEAQVCYTUBX-UHFFFAOYSA-N
SMILES :C1(COCCN)NC(C)=C(C(OC)=O)C(C2=CC=CC=C2Cl)C=1C(OCC)=O
CAS DataBase Reference :88150-42-9(CAS DataBase Reference)
EPA Substance Registry System :3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester (88150-42-9)

Safety Information

Symbol(GHS): Corrosion (GHS05)Skull and Crossbones (GHS06)Health Hazard (GHS08)Environment (GHS09)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning P273, P391, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

Amlodipine is a dihydropyridine L-type calcium channel blocker that selectively inhibits calcium influx in cardiac and vascular smooth muscle. Acting as a vasodilator, amlodipine reduces blood pressure by relaxing the smooth muscle in the arterial wall, decreasing total peripheral resistance. It inhibits calcium-induced contractions in depolarized rat aorta with an IC50 value of 1.9 nM, displaying a slow rate of association and dissociation in isolated vascular and cardiac tissues. When used in combination with the angiotensin receptor blocker olmesartan, amlopidine has been shown to potentiate antihypertensive activity. Amlodipine also demonstrates actions independent of L-type calcium channel blockade by regulating membrane fluidity and cholesterol deposition, stimulating nitric oxide production, acting as an antioxidant, and regulating matrix deposition.

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