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ChemicalBook >> CAS DataBase List >> Articaine

Articaine

Articaine price.
  • $65 - $1850
  • Product name: Articaine
  • CAS: 23964-58-1
  • MF: C13H20N2O3S
  • MW: 284.37
  • EINECS:607-295-0
  • MDL Number:MFCD00864454
  • Synonyms:ARTICAINE;methyl 4-methyl-3-(2-propylaminopropanoylamino)thiophene-2-carboxylate;4-Methyl-3-[2-[propylamino] propionamido]-2-thiophenecarboxylic acid, methyl ester;40045;4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester;4-Methyl-3-[1-oxo-2-(propylamino)propylamino]-2-thiophenecarboxylic acid methyl ester;Articaina [inn-spanish];Articainum
33 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AHH
  • American Custom Chemicals Corporation
  • AvaChem
  • Biorbyt Ltd
  • Biosynth
  • ChemScene
  • Medical Isotopes, Inc.
  • TCI Chemical
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 2g
  • 5g
  • Manufactureraablocks
  • Product numberAA00JGEF
  • Product descriptionArticaine 99%
  • Packaging250mg
  • Price$250
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00JGEF
  • Product descriptionArticaine 99%
  • Packaging1g
  • Price$650
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00JGEF
  • Product descriptionArticaine 99%
  • Packaging5g
  • Price$1850
  • Updated2026-05-29
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD259049
  • Product descriptionMethyl 4-methyl-3-[(N-propylalanyl)amino]thiophene-2-carboxylate hydrochloride 95%
  • Packaging1G
  • Price$295
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD259049
  • Product descriptionMethyl 4-methyl-3-[(N-propylalanyl)amino]thiophene-2-carboxylate hydrochloride 95%
  • Packaging250MG
  • Price$120
  • Updated2026-05-27
  • Buy
  • ManufacturerAHH
  • Product numberMT-47233
  • Product descriptionArticaine 98%
  • Packaging1g
  • Price$410
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-47233
  • Product descriptionArticaine 97%
  • Packaging1g
  • Price$410
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-47233
  • Product descriptionArticaine 97%
  • Packaging1g
  • Price$410
  • Updated2026-05-26
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008646
  • Product descriptionARTICAINE 95.00%
  • Packaging1G
  • Price$744.45
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number5378B
  • Product descriptionArticaine
  • Packaging100mg
  • Price$465
  • Updated2026-05-22
  • Buy
  • ManufacturerAvaChem
  • Product number5378B
  • Product descriptionArticaine
  • Packaging5mg
  • Price$65
  • Updated2026-05-22
  • Buy
  • ManufacturerAvaChem
  • Product number5378B
  • Product descriptionArticaine
  • Packaging25mg
  • Price$165
  • Updated2026-05-22
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134430
  • Product descriptionArticaine HCl >99%
  • Packaging250mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134430
  • Product descriptionArticaine HCl >99%
  • Packaging100mg
  • Price$414.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134430
  • Product descriptionArticaine HCl >99%
  • Packaging1g
  • Price$912.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFA147618
  • Product descriptionArticaine
  • Packaging2g
  • Price$676
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00JGEF Articaine 99% 250mg $250 2026-05-29 Buy
aablocks AA00JGEF Articaine 99% 1g $650 2026-05-29 Buy
aablocks AA00JGEF Articaine 99% 5g $1850 2026-05-29 Buy
ACHEMBLOCK AD259049 Methyl 4-methyl-3-[(N-propylalanyl)amino]thiophene-2-carboxylate hydrochloride 95% 1G $295 2026-05-27 Buy
ACHEMBLOCK AD259049 Methyl 4-methyl-3-[(N-propylalanyl)amino]thiophene-2-carboxylate hydrochloride 95% 250MG $120 2026-05-27 Buy
AHH MT-47233 Articaine 98% 1g $410 2021-12-16 Buy
AHH MT-47233 Articaine 97% 1g $410 2026-05-25 Buy
AHH MT-47233 Articaine 97% 1g $410 2026-05-26 Buy
American Custom Chemicals Corporation API0008646 ARTICAINE 95.00% 1G $744.45 2021-12-16 Buy
AvaChem 5378B Articaine 100mg $465 2026-05-22 Buy
AvaChem 5378B Articaine 5mg $65 2026-05-22 Buy
AvaChem 5378B Articaine 25mg $165 2026-05-22 Buy
Biorbyt Ltd orb134430 Articaine HCl >99% 250mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb134430 Articaine HCl >99% 100mg $414.8 2021-12-16 Buy
Biorbyt Ltd orb134430 Articaine HCl >99% 1g $912.9 2021-12-16 Buy
Biosynth FA147618 Articaine 2g $676 2021-12-16 Buy

Properties

Melting point :175-176 °C
Boiling point :bp0.3 162-167°
Density :1.178±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
pka :13.46±0.70(Predicted)
form :Solid
color :White to Off-White
Major Application :pharmaceutical (small molecule)
InChI :InChI=1S/C13H20N2O3S/c1-5-6-14-9(3)12(16)15-10-8(2)7-19-11(10)13(17)18-4/h7,9,14H,5-6H2,1-4H3,(H,15,16)
InChIKey :QTGIAADRBBLJGA-UHFFFAOYSA-N
SMILES :C1(C(OC)=O)SC=C(C)C=1NC(=O)C(NCCC)C
CAS DataBase Reference :23964-58-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Articaine [4-methyl-3-(2-propylaminopropionamido) thiophene-2-carboxylic acid methyl ester hydrochloride] has been widely used in dentistry since its approval by the U.S. FDA in the year 2000 because of its quick onset and short duration of action. The structure of articaine differs from those of all other amino amide-type local anesthetics in that it contains a thiophene ring instead of a benzene ring and a carbomethoxy group. This renders the molecule more lipophilic and, thus, easier to cross any lipoidal membranes.
Its local anesthetic potency is approximately 1.5-fold that of lidocaine, even though it has similar pKa (7.8) and plasma protein binding (76%) properties. Articaine also is metabolized primarily by plasma cholinesterases because of the presence of an ester group and, therefore, has a much shorter duration of action than lidocaine (i.e., only approximately one-fourth that of lidocaine). Articaine undergoes rapid hydrolysis of the carbomethoxy group to give articainic acid, which is eliminated either unchanged (75%) or as its glucuronides (25%). Compared with to other shortacting, amino amide-type local anesthetics, such as mepivacaine, lidocaine, or prilocaine, articaine is said to be a much safer drug for regional anesthesia and is the drug of choice for dental procedures.

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