Astemizole
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- $28 - $4545
- Product name: Astemizole
- CAS: 68844-77-9
- MF: C28H31FN4O
- MW: 458.57
- EINECS:272-441-9
- MDL Number:MFCD00153919
- Synonyms:1-((4-fluorophenyl)methyl)-n-(1-(2-(4-methoxyphenyl)ethyl)-4-piperidinyl)-1h-b ;r45312 ;retolen ;ASTEMIZOLE;1-[(4-FLUOROPHENYL)METHYL]-N-[1-[2-(4-METHOXYPHENYL)ETHYL]-4-PIPERIDINYL]-1H-BENZIMIDAZOL-2-AMINE;(1-[4-FLUOROBENZYL]-2-[1-(4-METHOXYPHENETHYL)PIPERIDIN-4-YL] AMINOBENZIMIDAZOLE;Astemisan;R 43512
49 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Medical Isotopes, Inc.
- Oakwood
- Sigma-Aldrich
- Thermo Scientific Chemicals
- Tocris
- TRC
Package
- 10mM(in1mLDMSO)
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 50
- 250mg
- 1G
- 5G
- Manufactureraablocks
- Product numberAA003DPX
- Product description1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine ≥98%
- Packaging10mg
- Price$28
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003DPX
- Product description1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine ≥98%
- Packaging25mg
- Price$54
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003DPX
- Product description1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine ≥98%
- Packaging50mg
- Price$102
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003DPX
- Product description1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine ≥98%
- Packaging100mg
- Price$190
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003DPX
- Product description1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine ≥98%
- Packaging250mg
- Price$429
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberT90181
- Product descriptionAstemizole 98%
- Packaging100MG
- Price$250
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT90181
- Product descriptionAstemizole 98%
- Packaging100MG
- Price$250
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT90181
- Product descriptionAstemizole 98%
- Packaging1G
- Price$1255
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT90181
- Product descriptionAstemizole 98%
- Packaging1G
- Price$1255
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT90181
- Product descriptionAstemizole 98%
- Packaging5G
- Price$4545
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberT90181
- Product descriptionAstemizole 98%
- Packaging5G
- Price$4545
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberK146
- Product descriptionAstemizole
- Packaging10mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002918
- Product descriptionASTEMIZOLE 95.00%
- Packaging10MG
- Price$165.9
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002918
- Product descriptionASTEMIZOLE 95.00%
- Packaging25MG
- Price$704.55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7409
- Product descriptionAstemizole
- Packaging100mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7409
- Product descriptionAstemizole
- Packaging100mg
- Price$140
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA003DPX | 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine ≥98% | 10mg | $28 | 2026-05-28 | Buy |
| aablocks | AA003DPX | 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine ≥98% | 25mg | $54 | 2026-05-28 | Buy |
| aablocks | AA003DPX | 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine ≥98% | 50mg | $102 | 2026-05-28 | Buy |
| aablocks | AA003DPX | 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine ≥98% | 100mg | $190 | 2026-05-28 | Buy |
| aablocks | AA003DPX | 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine ≥98% | 250mg | $429 | 2026-05-28 | Buy |
| ACHEMBLOCK | T90181 | Astemizole 98% | 100MG | $250 | 2026-05-25 | Buy |
| ACHEMBLOCK | T90181 | Astemizole 98% | 100MG | $250 | 2026-05-27 | Buy |
| ACHEMBLOCK | T90181 | Astemizole 98% | 1G | $1255 | 2026-05-25 | Buy |
| ACHEMBLOCK | T90181 | Astemizole 98% | 1G | $1255 | 2026-05-27 | Buy |
| ACHEMBLOCK | T90181 | Astemizole 98% | 5G | $4545 | 2026-05-25 | Buy |
| ACHEMBLOCK | T90181 | Astemizole 98% | 5G | $4545 | 2026-05-27 | Buy |
| AK Scientific | K146 | Astemizole | 10mg | $104 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002918 | ASTEMIZOLE 95.00% | 10MG | $165.9 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002918 | ASTEMIZOLE 95.00% | 25MG | $704.55 | 2021-12-16 | Buy |
| ApexBio Technology | B7409 | Astemizole | 100mg | $140 | 2021-12-16 | Buy |
| ApexBio Technology | B7409 | Astemizole | 100mg | $140 | 2026-05-06 | Buy |
Properties
Melting point :172.9°C
Boiling point :627.3±65.0 °C(Predicted)
Density :1.1587 (estimate)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
pka :pKa 4.85(H2O t=25.0 I=0.025) (Uncertain);8.69(H2O t=25.0 I=0.025) (Uncertain)
form :powder
color :Crystals
Water Solubility :It is soluble in DMSO (25 mg/ml ), ethanol (25 mg/ml), chloroform, methanol, and water (partly miscible).
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChI :1S/C28H31FN4O/c1-34-25-12-8-21(9-13-25)14-17-32-18-15-24(16-19-32)30-28-31-26-4-2-3-5-27(26)33(28)20-22-6-10-23(29)11-7-22/h2-13,24H,14-20H2,1H3,(H,30,31)
InChIKey :GXDALQBWZGODGZ-UHFFFAOYSA-N
SMILES :COc1ccc(CCN2CCC(CC2)Nc3nc4ccccc4n3Cc5ccc(F)cc5)cc1
Boiling point :627.3±65.0 °C(Predicted)
Density :1.1587 (estimate)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
pka :pKa 4.85(H2O t=25.0 I=0.025) (Uncertain);8.69(H2O t=25.0 I=0.025) (Uncertain)
form :powder
color :Crystals
Water Solubility :It is soluble in DMSO (25 mg/ml ), ethanol (25 mg/ml), chloroform, methanol, and water (partly miscible).
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChI :1S/C28H31FN4O/c1-34-25-12-8-21(9-13-25)14-17-32-18-15-24(16-19-32)30-28-31-26-4-2-3-5-27(26)33(28)20-22-6-10-23(29)11-7-22/h2-13,24H,14-20H2,1H3,(H,30,31)
InChIKey :GXDALQBWZGODGZ-UHFFFAOYSA-N
SMILES :COc1ccc(CCN2CCC(CC2)Nc3nc4ccccc4n3Cc5ccc(F)cc5)cc1
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Astemizole is a non-sedating antihistamine that antagonizes the histamine H1 receptor with a Ki value of 4.4 nM. It is considerably less potent at muscarinic acetylcholine receptors (Ki = 2.4 μM). Astemizole is also a potent blocker of ether-a-go-go-related gene (ERG) potassium channels (IC50 = ~1 nM) that has been used to study long QT syndrome type 2. Furthermore, because it can target oncogenic ERG1 and ERG potassium channels, astemizole has been explored as a potential antineoplastic agent for decreasing proliferation of various cancer cells.More related product prices
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Suppliers and manufacturers
Shanghai kingmorn biotechnology Co.,Ltd.
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
CONIER CHEM AND PHARMA LIMITED
Shaanxi Dideu Medichem Co. Ltd
AFINE CHEMICALS LIMITED
BOC Sciences
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Astemizole
CAS:68844-77-9