Avanafil
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- $5 - $1654
- Product name: Avanafil
- CAS: 330784-47-9
- MF: C23H26ClN7O3
- MW: 483.95
- EINECS:-0
- MDL Number:MFCD11977961
- Synonyms:4-[[(3-Chloro-4-Methoxyphenyl)Methyl] aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-N-(2-pyriMidinylMethyl)-5-pyriMidinecarboxaMide;Avanafil 4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide;(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-yl;avanafil:4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)-1-pyrrolidinyl)-n-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide: (s)-2-(2-hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylami;(S)-4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2pyrimidinylmethyl)-5-pyrimidinecarboxamide;(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine;4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide;Avanafil
65 prices
Selected condition：
Brand
- aablocks
- AccelPharmtech
- ACHEMBLOCK
- AK Scientific
- Alichem
- Ambeed
- ApexBio Technology
- Apolloscientific
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 10mM(in1mLDMSO)
- 250mg
- 500mg
- 10mM(in 1mL DMSO)
- 1g
- 1.00g
- 2g
- 5G
- 10g
- 25G
- 100G
- Manufactureraablocks
- Product numberAA0034EI
- Product description(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine 98%
- Packaging1mg
- Price$8
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0034EI
- Product description(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine 98%
- Packaging10mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0034EI
- Product description(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine 98%
- Packaging50mg
- Price$13
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0034EI
- Product description(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine 98%
- Packaging100mg
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0034EI
- Product description(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine 98%
- Packaging250mg
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0034EI
- Product description(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine 95%
- Packaging1g
- Price$20
- Updated2026-05-28
- Buy
- ManufacturerAccelPharmtech
- Product numberAT8094
- Product descriptionAvanafil 99%
- Packaging25G
- Price$200
- Updated2026-05-21
- Buy
- ManufacturerAccelPharmtech
- Product numberAT8094
- Product descriptionAvanafil 99%
- Packaging100G
- Price$560
- Updated2026-05-21
- Buy
- ManufacturerACHEMBLOCK
- Product number10454
- Product descriptionAvanafil 98%
- Packaging1G
- Price$30
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10454
- Product descriptionAvanafil 98%
- Packaging5G
- Price$80
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberZ5510
- Product descriptionAvanafil
- Packaging500mg
- Price$94
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ11129
- Product descriptionAvanafil
- Packaging25mg
- Price$79.2
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ11129
- Product descriptionAvanafil
- Packaging5mg
- Price$19.8
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberZ5510
- Product descriptionAvanafil
- Packaging1g
- Price$163
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number330784479
- Product descriptionAvanafil
- Packaging1g
- Price$168.21
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number330784479
- Product descriptionAvanafil
- Packaging5g
- Price$454.94
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0034EI | (S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine 98% | 1mg | $8 | 2026-05-28 | Buy |
| aablocks | AA0034EI | (S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine 98% | 10mg | $10 | 2026-05-28 | Buy |
| aablocks | AA0034EI | (S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine 98% | 50mg | $13 | 2026-05-28 | Buy |
| aablocks | AA0034EI | (S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine 98% | 100mg | $16 | 2026-05-28 | Buy |
| aablocks | AA0034EI | (S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine 98% | 250mg | $19 | 2026-05-28 | Buy |
| aablocks | AA0034EI | (S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine 95% | 1g | $20 | 2026-05-28 | Buy |
| AccelPharmtech | AT8094 | Avanafil 99% | 25G | $200 | 2026-05-21 | Buy |
| AccelPharmtech | AT8094 | Avanafil 99% | 100G | $560 | 2026-05-21 | Buy |
| ACHEMBLOCK | 10454 | Avanafil 98% | 1G | $30 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10454 | Avanafil 98% | 5G | $80 | 2026-05-27 | Buy |
| AK Scientific | Z5510 | Avanafil | 500mg | $94 | 2021-12-16 | Buy |
| AK Scientific | J11129 | Avanafil | 25mg | $79.2 | 2021-12-16 | Buy |
| AK Scientific | J11129 | Avanafil | 5mg | $19.8 | 2021-12-16 | Buy |
| AK Scientific | Z5510 | Avanafil | 1g | $163 | 2021-12-16 | Buy |
| Alichem | 330784479 | Avanafil | 1g | $168.21 | 2021-12-16 | Buy |
| Alichem | 330784479 | Avanafil | 5g | $454.94 | 2021-12-16 | Buy |
Properties
Melting point :150-152°C
Density :1.372
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :11.84±0.46(Predicted)
color :White to Off-White
InChIKey :WEAJZXNPAWBCOA-INIZCTEOSA-N
SMILES :C1(N2CCC[C@H]2CO)=NC=C(C(NCC2=NC=CC=N2)=O)C(NCC2=CC=C(OC)C(Cl)=C2)=N1
CAS DataBase Reference :330784-47-9(CAS DataBase Reference)
Density :1.372
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :11.84±0.46(Predicted)
color :White to Off-White
InChIKey :WEAJZXNPAWBCOA-INIZCTEOSA-N
SMILES :C1(N2CCC[C@H]2CO)=NC=C(C(NCC2=NC=CC=N2)=O)C(NCC2=CC=C(OC)C(Cl)=C2)=N1
CAS DataBase Reference :330784-47-9(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Avanafil (Zepeed) was approved by the Korean Health Ministry for the treatment of erectile dysfunction (ED) in August 2011. Avanafil is a highly selective type 5 phosphodiesterase (PDE5) inhibitor. Avanafil is reported to be the most selective PDE5 inhibitor on the market. The onset of Tmax and half-life also varies among the marketed PDE5 inhibitors. Sildenafil has a Tmax at 1 h and a half-life of 3–5 h. Vardenafil is somewhat similar with a Tmax of 0.6 h and a half-life of 4–6 h. Tadalafil has the longest half-life among the marketed drugs with a half-life of 17 h. Avanafil has a fast onset of action reaching Tmax in 0.6 h with a half-life of 1.2 h. A synthesis of avanafil (TA-1790) is described in the patent literature. The main elimination route of avanafil is through the bile and feces. Avanafil was also found to be reabsorbed through enterohepatic recirculation.More related product prices
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Suppliers and manufacturers
Guangzhou Tosun Pharmaceutical Ltd
Avanafil
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Forest chemical technology
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Hangzhou ICH Biofarm Co., Ltd
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Shaanxi Haibo Biotechnology Co., Ltd
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
Wuhan Mayue Longteng Technology Development Co., Ltd.
Wuhan Biocar Pharmacy CO.,Ltd.
Yiwu Fengjin Commercial Company
Avanafil
CAS:330784-47-9