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ChemicalBook >> CAS DataBase List >> Betulin

Betulin

Betulin price.
  • $10 - $1353.66
  • Product name: Betulin
  • CAS: 473-98-3
  • MF: C30H50O2
  • MW: 442.72
  • EINECS:207-475-5
  • MDL Number:MFCD00016802
  • Synonyms:Lup-20(29)-ene-3,28-diol, (3β)-;BETULIN(P);BETULIN hplc;Betulin,Betulinol,Betulol,Betulenol;3b,28-Dihydroxylup-20(29)-ene;SpirulinaPowder&Tablets;etulin;BETULIN WITH HPLC
107 prices
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  • aablocks
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
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  • Biorbyt Ltd
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  • Manufactureraablocks
  • Product numberAA00398S
  • Product descriptionBetulin 98%
  • Packaging1g
  • Price$10
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00398S
  • Product descriptionBetulin 98%
  • Packaging5g
  • Price$22
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00398S
  • Product descriptionBetulin 98%
  • Packaging10g
  • Price$38
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00398S
  • Product descriptionBetulin 98%
  • Packaging25g
  • Price$73
  • Updated2026-05-28
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0476-M250
  • Product descriptionBetulin ≥98%(NMR)
  • Packaging250mg
  • Price$45
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0476-G001
  • Product descriptionBetulin ≥98%(NMR)
  • Packaging1g
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0476-G001
  • Product descriptionBetulin ≥98%(NMR)
  • Packaging1g
  • Price$90
  • Updated2026-05-06
  • Buy
  • ManufacturerAHH
  • Product numberMT-47881
  • Product descriptionBetulinol 98%
  • Packaging5g
  • Price$280
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberMT-47881
  • Product descriptionBetulinol 97%
  • Packaging5g
  • Price$280
  • Updated2026-05-25
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  • ManufacturerAHH
  • Product numberMT-47881
  • Product descriptionBetulinol 97%
  • Packaging5g
  • Price$280
  • Updated2026-05-26
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  • ManufacturerAK Scientific
  • Product numberV0184
  • Product descriptionBetulin 98%(HPLC)
  • Packaging25g
  • Price$198
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberV0184
  • Product descriptionBetulin
  • Packaging25g
  • Price$324
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ90760
  • Product descriptionBetulin 95%
  • Packaging100g
  • Price$487
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberV0184
  • Product descriptionBetulin 98%(HPLC)
  • Packaging100g
  • Price$702
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ10870
  • Product descriptionBetulin >98%(HPLC),powder
  • Packaging5g
  • Price$90
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ90760
  • Product descriptionBetulin 95%
  • Packaging25g
  • Price$137
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00398S Betulin 98% 1g $10 2026-05-28 Buy
aablocks AA00398S Betulin 98% 5g $22 2026-05-28 Buy
aablocks AA00398S Betulin 98% 10g $38 2026-05-28 Buy
aablocks AA00398S Betulin 98% 25g $73 2026-05-28 Buy
Adipogen Life Sciences AG-CN2-0476-M250 Betulin ≥98%(NMR) 250mg $45 2026-05-06 Buy
Adipogen Life Sciences AG-CN2-0476-G001 Betulin ≥98%(NMR) 1g $90 2021-12-16 Buy
Adipogen Life Sciences AG-CN2-0476-G001 Betulin ≥98%(NMR) 1g $90 2026-05-06 Buy
AHH MT-47881 Betulinol 98% 5g $280 2021-12-16 Buy
AHH MT-47881 Betulinol 97% 5g $280 2026-05-25 Buy
AHH MT-47881 Betulinol 97% 5g $280 2026-05-26 Buy
AK Scientific V0184 Betulin 98%(HPLC) 25g $198 2026-06-04 Buy
AK Scientific V0184 Betulin 25g $324 2021-12-16 Buy
AK Scientific J90760 Betulin 95% 100g $487 2026-06-04 Buy
AK Scientific V0184 Betulin 98%(HPLC) 100g $702 2026-06-04 Buy
AK Scientific J10870 Betulin >98%(HPLC),powder 5g $90 2026-06-04 Buy
AK Scientific J90760 Betulin 95% 25g $137 2026-06-04 Buy

Properties

Melting point :256-257 °C(lit.)
alpha :D15 +20° (c = 2 in pyridine)
Boiling point :493.26°C (rough estimate)
Density :0.9882 (rough estimate)
refractive index :1.5045 (estimate)
storage temp. :2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly, Heated)
form :Off-white powder
pka :15.10±0.10(Predicted)
color :Pale Brown to Beige
optical activity :+2015 (c 6, pyridine)
Merck :14,1189
Stability :Hygroscopic
Major Application :food and beverages
Cosmetics Ingredients Functions :SKIN CONDITIONING
InChIKey :FVWJYYTZTCVBKE-ROUWMTJPSA-N
SMILES :[H][C@]12CC[C@]3([H])[C@@]4(C)CC[C@H](O)C(C)(C)[C@]4([H])CC[C@@]3(C)[C@]1(C)CC[C@@]5(CO)CC[C@@H](C(C)=C)[C@]25[H]
LogP :8.607 (est)
CAS DataBase Reference :473-98-3(CAS DataBase Reference)
NIST Chemistry Reference :Betulin(473-98-3)

Safety Information

Symbol(GHS): Health Hazard (GHS08)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H371 May cause damage to organs Specific target organ toxicity, single exposure Category 2 Warning P260, P264, P270, P309+P311, P405,P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Sterol regulatory element binding protein 2 (SREBP-2) regulates cholesterol synthesis by activating the transcription of genes for HMG-CoA reductase and other enzymes of the cholesterol synthetic pathway. When cellular sterol levels are high, SREBP is bound by SCAP and Insig to ER membranes as a glycosylated precursor protein. Upon cholesterol depletion, the protein is cleaved to its active form and translocated into the nucleus to stimulate transcription of genes involved in the uptake and synthesis of cholesterol. Betulin, the precursor of betulinic acid, is a pentacyclic triterpene found in the bark of birch trees. Betulin inhibits the SREBP-driven pathway of cholesterol and fatty acid biosynthesis by promoting SCAP–Insig binding which prevents the activation and release of SREBP-2 from the ER. At 15-30 mg/kg/day, betulin has been shown to decrease lipid levels and increase insulin sensitivity in mice fed a western-type diet. In an atherosclerosis disease model, 30 mg/kg/day betulin can reduce the size and improve the stability of atherosclerotic plaques in LDLR-knockout mice. At 2.5-5 μg/ml betulin, in combination with cholesterol, demonstrates anticancer effects by inducing apoptosis in Jurkat cells, A549 lung carcinoma cells, and HeLa cervical carcinoma cells.

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