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ChemicalBook >> CAS DataBase List >> Bicalutamide

Bicalutamide

Bicalutamide price.
  • $6 - $1960
  • Product name: Bicalutamide
  • CAS: 90357-06-5
  • MF: C18H14F4N2O4S
  • MW: 430.38
  • EINECS:200-001-8
  • MDL Number:MFCD00869971
  • Synonyms:(+-)--2-hydroxy-2-methyl ;propanamide,n-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)sulfonyl) ;Bicalutamide (Subject to patent free);ICI-176334;BICALUTAMIDE;N-[(4-CYANO-3-TRIFLUOROMETHYL)PHENYL]-3-[(4-FLUOROPHENYL)SULFONYL]-2-HYDROXY-2-METHYLPROPANAMIDE;N-[4-CYANO-3-(TRIFLUOROMETHYL)PHENYL]-3-[(4-FLUOROPHENYL)SULFONYL]-2-HYDROXY-2-METHYLPROPIONANILIDE;Bicalutamide&Int.
96 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AstaTech
  • AvaChem
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • Chem-Impex
  • Crysdot
  • CSNpharm
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
  • 10mg
  • 20mg
  • 50mg
  • 500mg
  • y0001448
  • 10
  • 50
  • 10 mg
  • y0001444
  • 160 mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 25mg
  • 100MG
  • 200mg
  • 250mg
  • 1g
  • 2.5g
  • 10mM*1mLinDMSO(Solution)
  • 100G
  • 10mM(in1mLDMSO)
  • 5g
  • 25g
  • Manufactureraablocks
  • Product numberAA00H0UA
  • Product descriptionPropanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl- 98%
  • Packaging5g
  • Price$52
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00H0UA
  • Product descriptionPropanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl- 98%
  • Packaging1g
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00H0UA
  • Product descriptionPropanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl- 98%
  • Packaging250mg
  • Price$7
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00H0UA
  • Product descriptionPropanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl- 98%
  • Packaging200mg
  • Price$6
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00H0UA
  • Product descriptionPropanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl- 98%
  • Packaging25g
  • Price$180
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT98935
  • Product descriptionN-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)sulfonyl)-2-hydroxy-2-methylpropanamide 95%
  • Packaging25G
  • Price$105
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT98935
  • Product descriptionN-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)sulfonyl)-2-hydroxy-2-methylpropanamide 95%
  • Packaging100G
  • Price$315
  • Updated2026-05-27
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-B0305-GG25
  • Product descriptionBicalutamide ≥98%(HPLC)
  • Packaging2.5g
  • Price$300
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-B0305-G001
  • Product descriptionBicalutamide ≥98%(HPLC)
  • Packaging1g
  • Price$150
  • Updated2026-05-06
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  • ManufacturerAK Scientific
  • Product numberG387
  • Product descriptionBicalutamide 98%(HPLC)
  • Packaging5g
  • Price$88
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberG387
  • Product descriptionBicalutamide 98%(HPLC)
  • Packaging1g
  • Price$27
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberG387
  • Product descriptionBicalutamide 98%(HPLC)
  • Packaging25g
  • Price$299
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberG387
  • Product descriptionBicalutamide
  • Packaging5g
  • Price$747
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberG387
  • Product descriptionBicalutamide 98%(HPLC)
  • Packaging100g
  • Price$911
  • Updated2026-06-04
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001710
  • Product descriptionBICALUTAMIDE 95.00%
  • Packaging1G
  • Price$1593.9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001710
  • Product descriptionBICALUTAMIDE 95.00%
  • Packaging100MG
  • Price$704.55
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00H0UA Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl- 98% 5g $52 2026-05-28 Buy
aablocks AA00H0UA Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl- 98% 1g $16 2026-05-28 Buy
aablocks AA00H0UA Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl- 98% 250mg $7 2026-05-28 Buy
aablocks AA00H0UA Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl- 98% 200mg $6 2026-05-28 Buy
aablocks AA00H0UA Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl- 98% 25g $180 2026-05-28 Buy
ACHEMBLOCK T98935 N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)sulfonyl)-2-hydroxy-2-methylpropanamide 95% 25G $105 2026-05-27 Buy
ACHEMBLOCK T98935 N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)sulfonyl)-2-hydroxy-2-methylpropanamide 95% 100G $315 2026-05-27 Buy
Adipogen Life Sciences CDX-B0305-GG25 Bicalutamide ≥98%(HPLC) 2.5g $300 2026-05-06 Buy
Adipogen Life Sciences CDX-B0305-G001 Bicalutamide ≥98%(HPLC) 1g $150 2026-05-06 Buy
AK Scientific G387 Bicalutamide 98%(HPLC) 5g $88 2026-06-04 Buy
AK Scientific G387 Bicalutamide 98%(HPLC) 1g $27 2026-06-04 Buy
AK Scientific G387 Bicalutamide 98%(HPLC) 25g $299 2026-06-04 Buy
AK Scientific G387 Bicalutamide 5g $747 2021-12-16 Buy
AK Scientific G387 Bicalutamide 98%(HPLC) 100g $911 2026-06-04 Buy
American Custom Chemicals Corporation API0001710 BICALUTAMIDE 95.00% 1G $1593.9 2021-12-16 Buy
American Custom Chemicals Corporation API0001710 BICALUTAMIDE 95.00% 100MG $704.55 2021-12-16 Buy

Properties

Melting point :191-193°C
Boiling point :650.3±55.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >5mg/mL
pka :11.49±0.29(Predicted)
form :powder
color :White to Off-White
λmax :270nm(CH3CN)(lit.)
Merck :14,1200
InChI :InChI=1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)
InChIKey :LKJPYSCBVHEWIU-UHFFFAOYSA-N
SMILES :C(NC1=CC=C(C#N)C(C(F)(F)F)=C1)(=O)C(O)(C)CS(C1=CC=C(F)C=C1)(=O)=O
CAS DataBase Reference :90357-06-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): Health Hazard (GHS08)Environment (GHS09)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P391 Collect spillage. Hazardous to the aquatic environment
P405 Store locked up.

Description

Bicalutamide is a non-steroidal androgen receptor antagonist that binds the androgen receptor (Ki = 12.5 μM; IC50 = 1.2 μM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones. Bicalutamide is frequently used to examine the role of androgen receptor inactivation in the proliferation of prostate cancer cells and has served as a molecular template for the design and structural optimization of more selective androgen receptor modulators for androgen therapy.

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