CAL-101
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- $18 - $3603.6
- Product name: CAL-101
- CAS: 870281-82-6
- MF: C22H18FN7O
- MW: 415.42
- EINECS:807-438-9
- MDL Number:MFCD19443647
- Synonyms:CAL101,CAL-101;CAL-101;GS1101;CAL-101 (GS-1101);5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone;CAL-101 (Idelalisib, GS-1101);(S)-2-(1-((9H-Purin-6-yl)aMino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;4(3H)-Quinazolinone, 5-fluoro-3-phenyl-2-[(1S)-1-(1H-purin-6-ylaMino)propyl]-
66 prices
Selected condition：
Brand
- aablocks
- Abosyn
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Matrix Scientific
- TRC
- Usbiological
Package
- EvaluationSample
- 1MG
- 5mg
- 10mg
- 50mg
- 20mg
- 100mg
- 10mM*1mLinDMSO
- 10mM(in1mLDMSO)
- 25mg
- 200mg
- 250mg
- 250.00mg
- 1.00g
- 1g
- 5.00g
- 5g
- 10g
- 25g
- 50G
- Manufactureraablocks
- Product numberAA00GTZ9
- Product description5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone 98%
- Packaging50mg
- Price$18
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTZ9
- Product description5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone 98%
- Packaging100mg
- Price$23
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTZ9
- Product description5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone 98%
- Packaging250mg
- Price$38
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTZ9
- Product description5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone 98%
- Packaging1g
- Price$94
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTZ9
- Product description5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone 98%
- Packaging5g
- Price$274
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTZ9
- Product description5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone 98%
- Packaging10g
- Price$474
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTZ9
- Product description5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone 98%
- Packaging25g
- Price$940
- Updated2026-05-28
- Buy
- ManufacturerAbosyn
- Product number61-10788
- Product description(S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 95-98%
- Packaging5g
- Price$675
- Updated2021-12-16
- Buy
- ManufacturerAbosyn
- Product number61-10788
- Product description(S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 95-98%
- Packaging1g
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerACHEMBLOCK
- Product number10335
- Product descriptionCAL-101 98%
- Packaging5G
- Price$240
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10335
- Product descriptionCAL-101 98%
- Packaging1G
- Price$80
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10335
- Product descriptionCAL-101 98%
- Packaging100MG
- Price$25
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5707
- Product descriptionCAL-101
- Packaging10mg
- Price$123
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5707
- Product descriptionCAL-101
- Packaging50mg
- Price$406
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024413
- Product descriptionCAL-101 95.00%
- Packaging1MG
- Price$667.01
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024413
- Product descriptionCAL-101 95.00%
- Packaging50G
- Price$3603.6
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GTZ9 | 5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone 98% | 50mg | $18 | 2026-05-28 | Buy |
| aablocks | AA00GTZ9 | 5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone 98% | 100mg | $23 | 2026-05-28 | Buy |
| aablocks | AA00GTZ9 | 5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone 98% | 250mg | $38 | 2026-05-28 | Buy |
| aablocks | AA00GTZ9 | 5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone 98% | 1g | $94 | 2026-05-28 | Buy |
| aablocks | AA00GTZ9 | 5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone 98% | 5g | $274 | 2026-05-28 | Buy |
| aablocks | AA00GTZ9 | 5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone 98% | 10g | $474 | 2026-05-28 | Buy |
| aablocks | AA00GTZ9 | 5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone 98% | 25g | $940 | 2026-05-28 | Buy |
| Abosyn | 61-10788 | (S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 95-98% | 5g | $675 | 2021-12-16 | Buy |
| Abosyn | 61-10788 | (S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 95-98% | 1g | $225 | 2021-12-16 | Buy |
| ACHEMBLOCK | 10335 | CAL-101 98% | 5G | $240 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10335 | CAL-101 98% | 1G | $80 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10335 | CAL-101 98% | 100MG | $25 | 2026-05-27 | Buy |
| AK Scientific | SYN5707 | CAL-101 | 10mg | $123 | 2021-12-16 | Buy |
| AK Scientific | SYN5707 | CAL-101 | 50mg | $406 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024413 | CAL-101 95.00% | 1MG | $667.01 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024413 | CAL-101 95.00% | 50G | $3603.6 | 2021-12-16 | Buy |
Properties
Melting point :250-252oC
Boiling point :733.4±70.0 °C(Predicted)
Density :1.47
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :White solid.
pka :10.00±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey :IFSDAJWBUCMOAH-HNNXBMFYSA-N
SMILES :N1C2=C(C(F)=CC=C2)C(=O)N(C2=CC=CC=C2)C=1[C@@H](NC1=C2C(=NC=N1)NC=N2)CC
Boiling point :733.4±70.0 °C(Predicted)
Density :1.47
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :White solid.
pka :10.00±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey :IFSDAJWBUCMOAH-HNNXBMFYSA-N
SMILES :N1C2=C(C(F)=CC=C2)C(=O)N(C2=CC=CC=C2)C=1[C@@H](NC1=C2C(=NC=N1)NC=N2)CC
Safety Information
| Symbol(GHS): |
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| Signal word: | Danger | ||||||||||||||
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Description
The phosphatidylinositol 3-kinase (PI3K) signaling pathway has central roles in cell growth, development, and survival. CAL-101 is a cell permeable inhibitor of the PI3K catalytic subunit p110δ (IC50 = 2.5 nM) that demonstrates 40- to 300-fold selectivity against other PI3K class I enzymes (IC50s = 820, 565, and 89 nM for p110α, β, and γ, respectively). At 1 μM it can block constitutive PI3K signaling in malignant B-cell lines and primary patient tumor cells, resulting in decreased phosphorylation of Akt and other downstream effectors, an increase in poly(ADP-ribose) polymerase, and apoptosis. It has also been shown to inhibit the chemotaxis of chronic lymphocytic leukemia cells and to downregulate the secretion of chemokines triggered by B-cell receptor signaling.More related product prices
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Suppliers and manufacturers
Changzhou Rokechem Technology Co., Ltd.
Idelalisib(CAL-101)
CAS:870281-82-6
Hebei Yanxi Chemical Co., Ltd.
Protheragen-ING
Capot Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Lianyungang happen teng technology co., LTD
Zhejiang ZETian Fine Chemicals Co. LTD
Biochempartner
Hangzhou Cyanochem Co., Ltd.
CAL-101
CAS:870281-82-6
