(-)-COTININE
|
- $8 - $2083
- Product name: (-)-COTININE
- CAS: 486-56-6
- MF: C10H12N2O
- MW: 176.22
- EINECS:207-634-9
- MDL Number:MFCD00077696
- Synonyms:L-COTININE;(-)-COTININE;(S)-(-)-1-METHYL-5-(3-PYRIDIYL)-2-PYRROLIDINONE;[S]-1-METHYL-5-[3-PYRIDYL]-2-PYRROLIDINONE;S(-)-1-METHYL-5-(3-PYRIDYL)-2-PYRROLIDONE;(s)-1-methyl-5-(3-pyridinyl)-2-pyrrolidinone ;(s)-2-pyrrolidinon ;1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone
75 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Ambeed
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- Matrix Scientific
- Sigma-Aldrich
- SynQuest Laboratories
- Thermo Scientific Chemicals
- TRC
- Usbiological
Package
- 10mg
- 20mg
- 100.00mg
- 250.00mg
- 0.25g
- 0.5g
- 500ul
- 1mL
- 1.00g
- 2g
- 10x1mL
- 1 mL
- 10mM*1mLinDMSO(Solution)
- 10mM(in 1mL DMSO)
- 1mg
- 5mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500MG
- 10mM(in1mLDMSO)
- 5g
- 1g
- 10mM*1mLinDMSO(Solidorliquid+Solvent)
- Manufactureraablocks
- Product numberAA00DEML
- Product description(S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98%
- Packaging1mg
- Price$8
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DEML
- Product description(S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one ≥98%
- Packaging5mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DEML
- Product description(S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one ≥98%
- Packaging25mg
- Price$18
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DEML
- Product description(S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98%
- Packaging100mg
- Price$33
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DEML
- Product description(S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 97%
- Packaging250mg
- Price$63
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DEML
- Product description(S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 97%
- Packaging5g
- Price$474
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DEML
- Product description(S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 97%
- Packaging1g
- Price$140
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberG-5334
- Product description(-)-Cotinine 97%
- Packaging500MG
- Price$250
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberG-5334
- Product description(-)-Cotinine 97%
- Packaging1G
- Price$420
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberG-5334
- Product description(-)-Cotinine 97%
- Packaging5G
- Price$2083
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA431146
- Product description(S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98+%
- Packaging250mg
- Price$114
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA431146
- Product description(S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98+%
- Packaging50mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA431146
- Product description(S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98+%
- Packaging100mg
- Price$76
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7277
- Product description(-)-Cotinine
- Packaging50mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7277
- Product description(-)-Cotinine
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7277
- Product description(-)-Cotinine
- Packaging10mM(in1mLDMSO)
- Price$61
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00DEML | (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98% | 1mg | $8 | 2026-05-28 | Buy |
| aablocks | AA00DEML | (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one ≥98% | 5mg | $10 | 2026-05-28 | Buy |
| aablocks | AA00DEML | (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one ≥98% | 25mg | $18 | 2026-05-28 | Buy |
| aablocks | AA00DEML | (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98% | 100mg | $33 | 2026-05-28 | Buy |
| aablocks | AA00DEML | (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 97% | 250mg | $63 | 2026-05-28 | Buy |
| aablocks | AA00DEML | (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 97% | 5g | $474 | 2026-05-28 | Buy |
| aablocks | AA00DEML | (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 97% | 1g | $140 | 2026-05-28 | Buy |
| ACHEMBLOCK | G-5334 | (-)-Cotinine 97% | 500MG | $250 | 2026-05-27 | Buy |
| ACHEMBLOCK | G-5334 | (-)-Cotinine 97% | 1G | $420 | 2026-05-27 | Buy |
| ACHEMBLOCK | G-5334 | (-)-Cotinine 97% | 5G | $2083 | 2021-12-16 | Buy |
| Ambeed | A431146 | (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98+% | 250mg | $114 | 2021-12-16 | Buy |
| Ambeed | A431146 | (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98+% | 50mg | $42 | 2021-12-16 | Buy |
| Ambeed | A431146 | (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98+% | 100mg | $76 | 2021-12-16 | Buy |
| ApexBio Technology | B7277 | (-)-Cotinine | 50mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | B7277 | (-)-Cotinine | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| ApexBio Technology | B7277 | (-)-Cotinine | 10mM(in1mLDMSO) | $61 | 2026-05-06 | Buy |
Properties
Melting point :40-42 °C(lit.)
alpha :[α]D20 -18～-22° (c=1, C2H5OH)
Boiling point :250 °C150 mm Hg(lit.)
Density :1.1102 (rough estimate)
refractive index :1.7110 (estimate)
Flash point :>230 °F
storage temp. :Sealed in dry,2-8°C
solubility :Chloroform (Sparingly), DMSO (Slightly), Methanol (Sparingly)
form :Solid
pka :4.72±0.12(Predicted)
color :Colourless to Very Dark Orange Oil
optical activity :[α]/D -21±2°, c = 1 in ethanol
Water Solubility :Not miscible or difficult to mix in water. Soluble in dimethyl sulfoxide (100 mM), ethanol (50 mg/ml, yielding a clear, faint yellow to yellow solution), methanol and chloroform.
Merck :14,2553
BRN :83099
Henry's Law Constant :3.0×106 mol/(m3Pa) at 25℃, HSDB (2015)
Stability :Stable. Incompatible with strong oxidizing agents. May be heat sensitive - store cold.
InChI :1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/t9-/m0/s1
InChIKey :UIKROCXWUNQSPJ-VIFPVBQESA-N
SMILES :CN1[C@@H](CCC1=O)c2cccnc2
EPA Substance Registry System :Cotinine (486-56-6)
alpha :[α]D20 -18～-22° (c=1, C2H5OH)
Boiling point :250 °C150 mm Hg(lit.)
Density :1.1102 (rough estimate)
refractive index :1.7110 (estimate)
Flash point :>230 °F
storage temp. :Sealed in dry,2-8°C
solubility :Chloroform (Sparingly), DMSO (Slightly), Methanol (Sparingly)
form :Solid
pka :4.72±0.12(Predicted)
color :Colourless to Very Dark Orange Oil
optical activity :[α]/D -21±2°, c = 1 in ethanol
Water Solubility :Not miscible or difficult to mix in water. Soluble in dimethyl sulfoxide (100 mM), ethanol (50 mg/ml, yielding a clear, faint yellow to yellow solution), methanol and chloroform.
Merck :14,2553
BRN :83099
Henry's Law Constant :3.0×106 mol/(m3Pa) at 25℃, HSDB (2015)
Stability :Stable. Incompatible with strong oxidizing agents. May be heat sensitive - store cold.
InChI :1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/t9-/m0/s1
InChIKey :UIKROCXWUNQSPJ-VIFPVBQESA-N
SMILES :CN1[C@@H](CCC1=O)c2cccnc2
EPA Substance Registry System :Cotinine (486-56-6)
Safety Information
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Description
Cotinine is a minor alkaloid found in tobacco plants and is a major metabolite of nicotine. It has a long pharmacological half-life (15-19 hours) compared to that of nicotine (2-3 hours) and is often used as a biomarker to detect tobacco use. Cotinine binds nicotinic- and muscarinic-type acetylcholine receptors with minimal receptor desensitization and demonstrates antipsychotic drug-like properties in behavioral models, neuroprotective properties in neurodegenerative disease models, and enhances attention in a delayed matching-to-sample task.Related product price
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