COUMERMYCIN A1
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- $158 - $1000
- Product name: COUMERMYCIN A1
- CAS: 4434-05-3
- MF: C55H59N5O20
- MW: 1110.08
- EINECS:
- MDL Number:MFCD00864860
- Synonyms:coumamycin ;coumermycins ;iyl)bis(carbonylimino))bis(7-((5,5-di-c-methyl-4-o-methyl-alpha-l-lyxopyranosy ;l)oxy)-4-hydroxy-8-methylcoumarin) ;notomycina1 ;pyrrole-2-carboxylicacid,5-methyl-,diesterwith3,3’-((3-methylpyrrole-2,4-d ;Cumamycin;N,N'-Bis[7-[[3-O-(5-methyl-1H-pyrrol-2-ylcarbonyl)-5-C-methyl-4-O-methyl-6-deoxy-α-L-lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-3-methyl-1H-pyrrole-2,4-dicarboxamide
7 prices
Selected condition：
Brand
- aablocks
- Arctom
- Sigma-Aldrich
Package
- 1mg
- 5mg
- 10mg
- 50mg
- Manufactureraablocks
- Product numberAA00D9VU
- Product descriptionCoumermycin A1 >98%
- Packaging5mg
- Price$758
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D9VU
- Product descriptionCoumermycin A1 >98%
- Packaging1mg
- Price$324
- Updated2026-05-28
- Buy
- ManufacturerArctom
- Product numberHY-N7452
- Product descriptionCoumermycin A1 99.86%
- Packaging1mg
- Price$363
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N7452
- Product descriptionCoumermycin A1 99.86%
- Packaging5mg
- Price$909
- Updated2026-05-26
- Buy
- ManufacturerSigma-Aldrich
- Product numberC9270
- Product descriptionCoumermycin A1
- Packaging50mg
- Price$1000
- Updated2023-06-20
- Buy
- ManufacturerSigma-Aldrich
- Product numberC9270
- Product descriptionCoumermycin A1
- Packaging5mg
- Price$158
- Updated2023-06-20
- Buy
- ManufacturerSigma-Aldrich
- Product numberC9270
- Product descriptionCoumermycin A1
- Packaging10mg
- Price$252
- Updated2023-06-20
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00D9VU | Coumermycin A1 >98% | 5mg | $758 | 2026-05-28 | Buy |
| aablocks | AA00D9VU | Coumermycin A1 >98% | 1mg | $324 | 2026-05-28 | Buy |
| Arctom | HY-N7452 | Coumermycin A1 99.86% | 1mg | $363 | 2026-05-26 | Buy |
| Arctom | HY-N7452 | Coumermycin A1 99.86% | 5mg | $909 | 2026-05-26 | Buy |
| Sigma-Aldrich | C9270 | Coumermycin A1 | 50mg | $1000 | 2023-06-20 | Buy |
| Sigma-Aldrich | C9270 | Coumermycin A1 | 5mg | $158 | 2023-06-20 | Buy |
| Sigma-Aldrich | C9270 | Coumermycin A1 | 10mg | $252 | 2023-06-20 | Buy |
Properties
Melting point :259°C (rough estimate)
Boiling point :821.5°C (rough estimate)
Density :1.1866 (rough estimate)
refractive index :1.7210 (estimate)
storage temp. :Store at -20°C
solubility :DMSO: 50 mg/mL, clear, faintly yellow
pka :pKa 6.0±0.02(H2O ) (Uncertain)
form :powder
color :White to off-white
BRN :470805
InChIKey :WTIJXIZOODAMJT-UHTWMVPANA-N
Boiling point :821.5°C (rough estimate)
Density :1.1866 (rough estimate)
refractive index :1.7210 (estimate)
storage temp. :Store at -20°C
solubility :DMSO: 50 mg/mL, clear, faintly yellow
pka :pKa 6.0±0.02(H2O ) (Uncertain)
form :powder
color :White to off-white
BRN :470805
InChIKey :WTIJXIZOODAMJT-UHTWMVPANA-N
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Coumermycin A1, a cell permeable antibiotic, has been found to be a dimerizing agent that can activate a modified Raf-1 protein and stimulate the mitogen-activated protein kinase cascade. This compound has also been reported to induce autophosphorylation of GyrB-Janus Kinase (JAK) 2 fusion proteins, thus bypassing receptor activation. JAKs are cytoplasmic protein kinases that interact with intracellular domains of cytokine receptors which plays an important role in signal transduction. The activation of JAK is thought to induce cell proliferation. Studies suggest that Coumermycin A1 can inhibit the supercoiling activity of gyrase by binding to the gyrase B subunit.More related product prices
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Suppliers and manufacturers
BOC Sciences
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd
Guangzhou Isun Pharmaceutical Co., Ltd
Shanghai EFE Biological Technology Co., Ltd.
Shanghai Chaolan Chemical Technology Center
Shenzhen SUNGENING Bio-Medical Co., Ltd.
Zhejiang Huida Biotech Co., LTD
Beijing Jin Ming Biotechnology Co., Ltd.