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ChemicalBook >> CAS DataBase List >> Chidamide

Chidamide

Chidamide price.
  • $26 - $1500
  • Product name: Chidamide
  • CAS: 743420-02-2
  • MF: C22H19FN4O2
  • MW: 390.41
  • EINECS:
  • MDL Number:MFCD18382123
  • Synonyms:(E)-N-(2-amino-5-fluorophenyl)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzamide Chidamide;Chidamide;(E)-N-(2-aMino-5-fluorophenyl)-4-((3-(pyridin-3-yl)acrylaMido)Methyl)benzaMide;N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propenyl]amino]methyl]benzamide;De-4-fluoro 5-Fluoro Chidamide;CHIDAMIDE;(E)-N-(2-AMINO-5-FLUOROPHENYL)-4-((3-(PYRIDIN-3-YL)ACRYLAMIDO)METHYL)BENZAMIDE;(E)-N-(2-AMINO-5-FLUOROPHENYL)-4-((3-(PYRIDIN-3-YL)ACRYLAMIDO)METHYL)BENZAMIDE CHIDAMIDE;N-(2-AMINO-5-FLUOROPHENYL)-4-[[[1-OXO-3-(3-PYRIDINYL)-2-PROPENYL]AMINO]METHYL;N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propenyl]amino]methyl;Chidamide D4
58 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
  • Usbiological
Package
  • 2mg
  • 10mM*1mLinDMSO
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 250mg
  • 1G
  • 10mM(in1mLDMSO)
  • 10mM(in 1mL DMSO)
  • Manufactureraablocks
  • Product numberAA00FBFX
  • Product descriptionChidamide 98%
  • Packaging50mg
  • Price$99
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FBFX
  • Product descriptionChidamide 98%
  • Packaging25mg
  • Price$83
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FBFX
  • Product descriptionChidamide 98%
  • Packaging10mg
  • Price$68
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FBFX
  • Product descriptionChidamide 98%
  • Packaging5mg
  • Price$57
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FBFX
  • Product descriptionChidamide ≥98%
  • Packaging1mg
  • Price$44
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33892
  • Product descriptionChidamide 98%
  • Packaging1G
  • Price$723
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33892
  • Product descriptionChidamide 98%
  • Packaging5MG
  • Price$26
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33892
  • Product descriptionChidamide 98%
  • Packaging25MG
  • Price$77
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33892
  • Product descriptionChidamide 98%
  • Packaging100MG
  • Price$166
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number1671AH
  • Product descriptionChidamide
  • Packaging25mg
  • Price$395
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA186722
  • Product descriptionChidamide 98+%
  • Packaging25mg
  • Price$469
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA186722
  • Product descriptionChidamide 98+%
  • Packaging10mg
  • Price$276
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA186722
  • Product descriptionChidamide 98+%
  • Packaging5mg
  • Price$163
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0105894
  • Product descriptionN-(2-AMINO-5-FLUOROPHENYL)-4-(((1-OXO-3-(3-PYRIDINYL)-2-PROPEN-1-YL)AMINO)METHYL)-BENZAMIDE 95.00%
  • Packaging1MG
  • Price$153.3
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5916
  • Product descriptionChidamide
  • Packaging5mg
  • Price$154
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5916
  • Product descriptionChidamide
  • Packaging10mM(in1mLDMSO)
  • Price$160
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00FBFX Chidamide 98% 50mg $99 2026-05-28 Buy
aablocks AA00FBFX Chidamide 98% 25mg $83 2026-05-28 Buy
aablocks AA00FBFX Chidamide 98% 10mg $68 2026-05-28 Buy
aablocks AA00FBFX Chidamide 98% 5mg $57 2026-05-28 Buy
aablocks AA00FBFX Chidamide ≥98% 1mg $44 2026-05-28 Buy
ACHEMBLOCK O33892 Chidamide 98% 1G $723 2026-05-27 Buy
ACHEMBLOCK O33892 Chidamide 98% 5MG $26 2026-05-27 Buy
ACHEMBLOCK O33892 Chidamide 98% 25MG $77 2026-05-27 Buy
ACHEMBLOCK O33892 Chidamide 98% 100MG $166 2026-05-27 Buy
AK Scientific 1671AH Chidamide 25mg $395 2021-12-16 Buy
Ambeed A186722 Chidamide 98+% 25mg $469 2021-12-16 Buy
Ambeed A186722 Chidamide 98+% 10mg $276 2021-12-16 Buy
Ambeed A186722 Chidamide 98+% 5mg $163 2021-12-16 Buy
American Custom Chemicals Corporation HCH0105894 N-(2-AMINO-5-FLUOROPHENYL)-4-(((1-OXO-3-(3-PYRIDINYL)-2-PROPEN-1-YL)AMINO)METHYL)-BENZAMIDE 95.00% 1MG $153.3 2021-12-16 Buy
ApexBio Technology B5916 Chidamide 5mg $154 2026-05-06 Buy
ApexBio Technology B5916 Chidamide 10mM(in1mLDMSO) $160 2026-05-06 Buy

Properties

Melting point :>145°C (dec.)
Boiling point :600.2±55.0 °C(Predicted)
Density :1.336±0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
form :Solid
pka :12.30±0.70(Predicted)
color :Off-White to Pale Beige
InChI :InChI=1S/C22H19FN4O2/c23-18-8-9-19(24)20(12-18)27-22(29)17-6-3-16(4-7-17)14-26-21(28)10-5-15-2-1-11-25-13-15/h1-13H,14,24H2,(H,26,28)(H,27,29)
InChIKey :WXHHICFWKXDFOW-UHFFFAOYSA-N
SMILES :C(NC1=CC(F)=CC=C1N)(=O)C1=CC=C(CNC(=O)C=CC2=CC=CN=C2)C=C1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Chidamide is a histone deacetylase inhibitor that increases histone H3 acetylation levels in LoVo and HT-29 colon cancer cells at concentrations as low as 4 μM. Additionally, chidamide affects the activation of oncogenic signaling kinases by dose-dependently reducing phosphorylated Akt, mTOR, p70S6k, Raf, and Erk1/2 protein expression in colon cancer cells. Furthermore, chidamide treatment dose-dependently upregulates p21 protein expression, downregulates Cdk4, and induces cell cycle arrest at the G0/G1 phase.

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