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ChemicalBook >> CAS DataBase List >> Collagenase

Collagenase

Collagenase price.
  • $24 - $6700
  • Product name: Collagenase
  • CAS: 9001-12-1
  • MF: C60H100N2
  • MW: 849.4494
  • EINECS:232-582-9
  • MDL Number:MFCD00130830
  • Synonyms:COLLAGENASE TYPE X;collagenase crude type ia cell culture*tested;collagenase F. clostridium histolyticum;collagenase from achromobacter iophagus;collagenase sterile filtered type vii-S;collagenase type I-S;Matrix metalloprotease-1;Metallocollagenase
135 prices
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  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Arctom
  • Biorbyt Ltd
  • Biosynth
  • Sigma-Aldrich
  • Thermo Scientific Chemicals
Package
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  • ManufacturerACHEMBLOCK
  • Product numberZ238752
  • Product descriptionCollagenase Type I 98%
  • Packaging1G
  • Price$315
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberZ238752
  • Product descriptionCollagenase Type I 98%
  • Packaging5G
  • Price$1260
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberM207
  • Product descriptionCollagenase
  • Packaging100mg
  • Price$128
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberENZ0000288
  • Product descriptionCLOSTRIDIOPEPTIDASE A 95.00%
  • Packaging30MG
  • Price$414.7
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberENZ0000288
  • Product descriptionCLOSTRIDIOPEPTIDASE A 95.00%
  • Packaging120MG
  • Price$458.8
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberENZ0001125
  • Product descriptionCOLLAGENASE TYPE X 95.00%
  • Packaging5MG
  • Price$499.95
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberENZ0000288
  • Product descriptionCLOSTRIDIOPEPTIDASE A 95.00%
  • Packaging300MG
  • Price$547
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIPR1005
  • Product descriptionRecombinantCollagenaseH >95%
  • Packaging5000CDU
  • Price$573
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIPR1003
  • Product descriptionRecombinantCollagenaseG/H >70%
  • Packaging1g
  • Price$573
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIPR1005
  • Product descriptionRecombinantCollagenaseH >95%
  • Packaging2000CDU
  • Price$312
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIPR1003
  • Product descriptionRecombinantCollagenaseG/H >70%
  • Packaging500mg
  • Price$319
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberHY-E70005D
  • Product descriptionCollagenase IV, Clostridium histolytica
  • Packaging500mg
  • Price$247
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-E70005I
  • Product descriptionCollagenase, Type VI
  • Packaging50mg
  • Price$263
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-E70005A
  • Product descriptionCollagenase, Type I
  • Packaging500mg
  • Price$285
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-E70005E
  • Product descriptionCollagenase, Type V
  • Packaging50mg
  • Price$131
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-E70005D
  • Product descriptionCollagenase IV, Clostridium histolytica
  • Packaging200mg
  • Price$124
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ACHEMBLOCK Z238752 Collagenase Type I 98% 1G $315 2026-05-27 Buy
ACHEMBLOCK Z238752 Collagenase Type I 98% 5G $1260 2026-05-27 Buy
AK Scientific M207 Collagenase 100mg $128 2021-12-16 Buy
American Custom Chemicals Corporation ENZ0000288 CLOSTRIDIOPEPTIDASE A 95.00% 30MG $414.7 2021-12-16 Buy
American Custom Chemicals Corporation ENZ0000288 CLOSTRIDIOPEPTIDASE A 95.00% 120MG $458.8 2021-12-16 Buy
American Custom Chemicals Corporation ENZ0001125 COLLAGENASE TYPE X 95.00% 5MG $499.95 2021-12-16 Buy
American Custom Chemicals Corporation ENZ0000288 CLOSTRIDIOPEPTIDASE A 95.00% 300MG $547 2021-12-16 Buy
Apolloscientific BIPR1005 RecombinantCollagenaseH >95% 5000CDU $573 2021-12-16 Buy
Apolloscientific BIPR1003 RecombinantCollagenaseG/H >70% 1g $573 2021-12-16 Buy
Apolloscientific BIPR1005 RecombinantCollagenaseH >95% 2000CDU $312 2021-12-16 Buy
Apolloscientific BIPR1003 RecombinantCollagenaseG/H >70% 500mg $319 2021-12-16 Buy
Arctom HY-E70005D Collagenase IV, Clostridium histolytica 500mg $247 2026-05-26 Buy
Arctom HY-E70005I Collagenase, Type VI 50mg $263 2026-05-26 Buy
Arctom HY-E70005A Collagenase, Type I 500mg $285 2026-05-26 Buy
Arctom HY-E70005E Collagenase, Type V 50mg $131 2026-05-26 Buy
Arctom HY-E70005D Collagenase IV, Clostridium histolytica 200mg $124 2026-05-26 Buy

Properties

storage temp. :-20°C
solubility :Soluble in aqueous buffers.
form :powder
color :light brown
PH :7.0
biological source :Clostridium histolyticum
Water Solubility :water: soluble
Merck :2481
Specific Activity :0.5-5.0FALGPA units/mg solid
InChIKey :YRQNKMKHABXEJZ-UVQQGXFZSA-N
CAS DataBase Reference :9001-12-1
EPA Substance Registry System :Collagenase (9001-12-1)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger P261, P285, P304+P341, P342+P311,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

Description

Collagenases are a category of enzymes that can digest native collagen, the major fibrous component of animal extracellular connective tissue. Collagenases can be produced by some bacterias such as Clostridium  and can also be made by the animal body as part of its normal immune response. They normally target the connective tissue in muscle cells and other body organs. They can break peptide bonds within collagen and help create collagen by cleaving pro-collagen, collagen's precursor, once it is secreted by the cell. Bacterial collagenases exhibit broader substrate specificity than animal collagenases and unlike animal collagenases that split collagen in its native triple-helical conformation, bacterial collagenase can degrade both water-insoluble native collagens and water-soluble denatured ones. In addition, bacterial collagenase can attack almost all collagen types, and is able to make multiple cleavages within triple helical regions.  Collagenases have a molecular weight ranging from 68 kilodaltons (kDa) to 130 Kda due to differing sizes based on the class to which the isolate belongs. The optimal pH for stability ranges from approximately 6.3 to 7.5 with a theoretical isoelectric point of 5.62. Numerous compounds and molecules have the capability of acting as collagenases activator or inhibitor. For example, Ca2+ and Zn2+ ions are two known activators. On the other hand, ethylenediaminetetraacetic acid (EDTA), ethylene glycol tetraacetic acid (EGTA), cysteine, histidine, dithiothreitol (DTT), 2-mercaptoethanol, o-phenanthroline, Hg2+, Pb2+, Cd2+, Cu2+, and Zn2+ are all known inhibitors of collagenase activity.

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