Cyclosporin A
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- $10 - $2759
- Product name: Cyclosporin A
- CAS: 59865-13-3
- MF: C62H111N11O12
- MW: 1202.61
- EINECS:611-907-1
- MDL Number:MFCD00274558
- Synonyms:ol27-400 ;s7481f1 ;sandimmun ;1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane, cyclic peptide deriv.;Cipol N;Neoplanta;(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-[(E,1R,2R)-1-hydroxy-2-methyl-hex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-dipropan-2-yl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,;(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-)
152 prices
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Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mg
- 50mg
- 10mM*1mLinDMSO(Solution)
- 5mg
- 20mg
- 25mg
- y0000361
- 100
- 250mg
- c2163000
- 200mg
- 10mM*1mLinDMSO
- 100mg
- 5x100mg
- 500mg
- 1ml
- 1.00g
- 1g
- 1000mg
- 4g
- 5g
- 10g
- 25g
- 1 g
- 5 g
- 100 mg
- 50g
- 100g
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA00IKFF
- Product descriptionCyclosporin A ≥98%
- Packaging250mg
- Price$11
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IKFF
- Product descriptionCyclosporin A >98%
- Packaging1g
- Price$15
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IKFF
- Product descriptionCyclosporin A >98%
- Packaging5g
- Price$30
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IKFF
- Product descriptionCyclosporin A >98%
- Packaging10g
- Price$60
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IKFF
- Product descriptionCyclosporin A >98%
- Packaging25g
- Price$135
- Updated2026-05-29
- Buy
- ManufacturerACHEMBLOCK
- Product numberU106466
- Product descriptionCyclosporin A 98.00%
- Packaging25G
- Price$160
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0079-G001
- Product descriptionCyclosporin A ≥98%
- Packaging1g
- Price$170
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0079-5100
- Product descriptionCyclosporin A ≥98%
- Packaging5x100mg
- Price$150
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-C0365-M100
- Product descriptionCyclosporin A ≥98%(HPLC)
- Packaging100mg
- Price$238
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0079-5100
- Product descriptionCyclosporin A ≥98%
- Packaging5x100mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-C0365-M025
- Product descriptionCyclosporin A ≥98%(HPLC)
- Packaging25mg
- Price$81
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0079-M100
- Product descriptionCyclosporin A ≥98%
- Packaging100mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0079-M100
- Product descriptionCyclosporin A ≥98%
- Packaging100mg
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberH890
- Product descriptionCyclosporin A 98%(HPLC)
- Packaging1g
- Price$46
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberH890
- Product descriptionCyclosporin A 98%(HPLC)
- Packaging250mg
- Price$16
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ99326
- Product descriptionCyclosporin A 95%
- Packaging1g
- Price$32
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00IKFF | Cyclosporin A ≥98% | 250mg | $11 | 2026-05-29 | Buy |
| aablocks | AA00IKFF | Cyclosporin A >98% | 1g | $15 | 2026-05-29 | Buy |
| aablocks | AA00IKFF | Cyclosporin A >98% | 5g | $30 | 2026-05-29 | Buy |
| aablocks | AA00IKFF | Cyclosporin A >98% | 10g | $60 | 2026-05-29 | Buy |
| aablocks | AA00IKFF | Cyclosporin A >98% | 25g | $135 | 2026-05-29 | Buy |
| ACHEMBLOCK | U106466 | Cyclosporin A 98.00% | 25G | $160 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CN2-0079-G001 | Cyclosporin A ≥98% | 1g | $170 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0079-5100 | Cyclosporin A ≥98% | 5x100mg | $150 | 2026-05-06 | Buy |
| Adipogen Life Sciences | CDX-C0365-M100 | Cyclosporin A ≥98%(HPLC) | 100mg | $238 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0079-5100 | Cyclosporin A ≥98% | 5x100mg | $135 | 2021-12-16 | Buy |
| Adipogen Life Sciences | CDX-C0365-M025 | Cyclosporin A ≥98%(HPLC) | 25mg | $81 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0079-M100 | Cyclosporin A ≥98% | 100mg | $45 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0079-M100 | Cyclosporin A ≥98% | 100mg | $50 | 2026-05-06 | Buy |
| AK Scientific | H890 | Cyclosporin A 98%(HPLC) | 1g | $46 | 2026-06-04 | Buy |
| AK Scientific | H890 | Cyclosporin A 98%(HPLC) | 250mg | $16 | 2026-06-04 | Buy |
| AK Scientific | J99326 | Cyclosporin A 95% | 1g | $32 | 2026-06-04 | Buy |
Properties
Melting point :148-151°C
Boiling point :838.63°C (rough estimate)
alpha :D20 -244° (c = 0.6 in chloroform); D20 -189° (c = 0.5 in methanol)
Density :0.9913 (rough estimate)
refractive index :1.6500 (estimate)
Flash point :87℃
storage temp. :-20°C
solubility :ethanol: 30 mg/mL
form :solid
pka :13.32±0.70(Predicted)
color :white
optical activity :-18922 (methanol)
Water Solubility :Soluble in dimethyl sulfoxide and ethanol. Insoluble in water.
Merck :14,2752
BRN :3647785
Stability :Stable for 3 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :PMATZTZNYRCHOR-CGLBZJNRSA-N
CAS DataBase Reference :59865-13-3(CAS DataBase Reference)
IARC :1 (Vol. 50, 100A) 2012
EPA Substance Registry System :Cyclosporin A (59865-13-3)
Boiling point :838.63°C (rough estimate)
alpha :D20 -244° (c = 0.6 in chloroform); D20 -189° (c = 0.5 in methanol)
Density :0.9913 (rough estimate)
refractive index :1.6500 (estimate)
Flash point :87℃
storage temp. :-20°C
solubility :ethanol: 30 mg/mL
form :solid
pka :13.32±0.70(Predicted)
color :white
optical activity :-18922 (methanol)
Water Solubility :Soluble in dimethyl sulfoxide and ethanol. Insoluble in water.
Merck :14,2752
BRN :3647785
Stability :Stable for 3 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :PMATZTZNYRCHOR-CGLBZJNRSA-N
CAS DataBase Reference :59865-13-3(CAS DataBase Reference)
IARC :1 (Vol. 50, 100A) 2012
EPA Substance Registry System :Cyclosporin A (59865-13-3)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Cyclosporin A is an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells (IC50 = 5 nM). It blocks the transcription of genes involved in T cell activation by interfering with the calcineurin-driven nuclear import of the transcription factor NFAT. Because of its powerful immunosuppressant activity, cyclosporin A has long been used for the prevention of transplant rejection.More related product prices
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Cyclosporin A
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