DESMETHYL SILDENAFIL
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- $28 - $1593.9
- Product name: DESMETHYL SILDENAFIL
- CAS: 139755-82-1
- MF: C21H28N6O4S
- MW: 460.55
- EINECS:
- MDL Number:MFCD00908398
- Synonyms:DESMETHYL SILDENAFIL;5-[2-Ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl- 7H-pyrazolo[4,3-d]pyrimidin-7-one;UK 103320;Sildenafil N-DesMethyl IMpurity;5-(2-Ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one;Sildenafil N-desmethyl;Sildenafil N-desmethy impurity;Sildenafil EP Impurity F (Sildenafil N-Desmethyl Metabolite)
62 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Chemtos
- Crysdot
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 1mg
- 2mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 0.25g
- 0.5g
- 1g
- 5g
- 10g
- 25g
- Manufactureraablocks
- Product numberAA007Z0M
- Product description5-[2-Ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one 95%
- Packaging250mg
- Price$39
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007Z0M
- Product description5-[2-Ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one ≥99%
- Packaging50mg
- Price$28
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007Z0M
- Product description5-[2-Ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one 95%
- Packaging1g
- Price$79
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007Z0M
- Product description5-[2-Ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one 95%
- Packaging5g
- Price$255
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product numberY0500
- Product descriptionN-Desmethylsildenafil
- Packaging5g
- Price$721
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ11755
- Product descriptionSildenafilEPImpurityF(N-DesmethylSildenafil)
- Packaging1g
- Price$894
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ55575
- Product descriptionN-Desmethylsildenafil
- Packaging10g
- Price$900
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ11755
- Product descriptionSildenafilEPImpurityF(N-DesmethylSildenafil)
- Packaging25mg
- Price$94
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156415
- Product description5-(2-Ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one 95%
- Packaging5g
- Price$324
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156415
- Product description5-(2-Ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one 95%
- Packaging250mg
- Price$44
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156415
- Product description5-(2-Ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one 95%
- Packaging1g
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0046132
- Product descriptionSILDENAFIL PIPERAZINE IMPURITY 95.00%
- Packaging5MG
- Price$457.51
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberMTB0000257
- Product descriptionN-DESMETHYL SILDENAFIL 95.00%
- Packaging5MG
- Price$738.1
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberMTB0000257
- Product descriptionN-DESMETHYL SILDENAFIL 95.00%
- Packaging50MG
- Price$1593.9
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4642
- Product descriptionN-Desmethyl Sildenafil
- Packaging5mg
- Price$171
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4642
- Product descriptionN-Desmethyl Sildenafil
- Packaging25mg
- Price$542
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA007Z0M | 5-[2-Ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one 95% | 250mg | $39 | 2026-05-28 | Buy |
| aablocks | AA007Z0M | 5-[2-Ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one ≥99% | 50mg | $28 | 2026-05-28 | Buy |
| aablocks | AA007Z0M | 5-[2-Ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one 95% | 1g | $79 | 2026-05-28 | Buy |
| aablocks | AA007Z0M | 5-[2-Ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one 95% | 5g | $255 | 2026-05-28 | Buy |
| AK Scientific | Y0500 | N-Desmethylsildenafil | 5g | $721 | 2021-12-16 | Buy |
| AK Scientific | J11755 | SildenafilEPImpurityF(N-DesmethylSildenafil) | 1g | $894 | 2021-12-16 | Buy |
| AK Scientific | J55575 | N-Desmethylsildenafil | 10g | $900 | 2021-12-16 | Buy |
| AK Scientific | J11755 | SildenafilEPImpurityF(N-DesmethylSildenafil) | 25mg | $94 | 2021-12-16 | Buy |
| Ambeed | A156415 | 5-(2-Ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one 95% | 5g | $324 | 2021-12-16 | Buy |
| Ambeed | A156415 | 5-(2-Ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one 95% | 250mg | $44 | 2021-12-16 | Buy |
| Ambeed | A156415 | 5-(2-Ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one 95% | 1g | $115 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0046132 | SILDENAFIL PIPERAZINE IMPURITY 95.00% | 5MG | $457.51 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | MTB0000257 | N-DESMETHYL SILDENAFIL 95.00% | 5MG | $738.1 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | MTB0000257 | N-DESMETHYL SILDENAFIL 95.00% | 50MG | $1593.9 | 2021-12-16 | Buy |
| ApexBio Technology | A4642 | N-Desmethyl Sildenafil | 5mg | $171 | 2026-05-06 | Buy |
| ApexBio Technology | A4642 | N-Desmethyl Sildenafil | 25mg | $542 | 2026-05-06 | Buy |
Properties
Melting point :158-160°C
Density :1.44±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMF: 5 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.15 mg/ml
form :A crystalline solid
pka :10.05±0.20(Predicted)
color :White to off-white
Stability :Moisture Sensitive
Density :1.44±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMF: 5 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.15 mg/ml
form :A crystalline solid
pka :10.05±0.20(Predicted)
color :White to off-white
Stability :Moisture Sensitive
Safety Information
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Description
Sildenafil is a potent cGMP-specific phosphodiesterase (PDE) inhibitor that is highly selective for PDE5 (IC50 = 3.6 nM). Inhibition of PDE5 prolongs nitric oxide-mediated relaxation of smooth muscle in a range of vascular tissues. N-Desmethyl sildenafil is a major metabolite of sildenafil. The conversion of sildenafil to this metabolite is affected by age and by renal and hepatic impairment.Related product price
-
Thiosildenafil
$43-1306.31 -
Desethyl Sildenafil
$149-1947 -
1391053-95-4
$94-9000
Suppliers and manufacturers
Moxin Chemicals
Standardpharm Co. Ltd.
Career Henan Chemica Co
sgtlifesciences pvt ltd
HANGZHOU LEAP CHEM CO., LTD.
Zibo Hangyu Biotechnology Development Co., Ltd
Shanghai Acmec Biochemical Technology Co., Ltd.
Aladdin Scientific
Sildenafil EP Impurity F
CAS:139755-82-1
