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ChemicalBook >> CAS DataBase List >> Doxazosin mesylate

Doxazosin mesylate

Doxazosin mesylate  price.
  • $9 - $1800
  • Product name: Doxazosin mesylate
  • CAS: 77883-43-3
  • MF: C24H29N5O8S
  • MW: 547.58
  • EINECS:1308068-626-2
  • MDL Number:MFCD00216023
  • Synonyms:ALFADIL;CARDENALIN;DOXAZOSIN MESYLATE;DOXAZOSIN METHANESULFONATE;UK-33274-27;doxazosinmesylate(patented-nosupply) ;piperazine,1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((2,3-dihydro-1,4-benzod ;DOXAZOSIN MEYLATE
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  • 10mM(in1mLDMSO)
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  • Product numberAA00ICTO
  • Product descriptionDoxazosin mesylate 99%
  • Packaging1mg
  • Price$9
  • Updated2026-05-29
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  • Product descriptionDoxazosin mesylate ≥99%
  • Packaging50mg
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  • Updated2026-05-29
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  • Product numberJ10294
  • Product descriptionDoxazosin mesylate 99%(HPLC),powder
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  • Updated2026-06-04
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00ICTO Doxazosin mesylate 99% 1mg $9 2026-05-29 Buy
aablocks AA00ICTO Doxazosin mesylate ≥99% 50mg $10 2026-05-29 Buy
aablocks AA00ICTO Doxazosin mesylate ≥99% 100mg $11 2026-05-29 Buy
aablocks AA00ICTO Doxazosin mesylate 99% 250mg $16 2026-05-29 Buy
aablocks AA00ICTO Doxazosin mesylate 99% 1g $20 2026-05-29 Buy
aablocks AA00ICTO Doxazosin mesylate 99% 5g $72 2026-05-29 Buy
aablocks AA00ICTO Doxazosin mesylate 99% 25g $222 2026-05-29 Buy
ACHEMBLOCK Z238020 Doxazosin mesylate 98% 25G $435 2026-05-27 Buy
ACHEMBLOCK Z238020 Doxazosin mesylate 98% 5G $140 2026-05-27 Buy
AHH API-1545 Doxazosin Mesylate 98% 10g $680 2021-12-16 Buy
AHH API-1545 Doxazosin mesylate 97% 10g $680 2026-05-26 Buy
AK Scientific A730 Doxazosin Mesylate 10g $534 2021-12-16 Buy
AK Scientific A730 Doxazosin mesylate 98%(HPLC) 5g $126 2026-06-04 Buy
AK Scientific J93654 Doxazosin mesylate 95% 5g $91 2026-06-04 Buy
AK Scientific A730 Doxazosin mesylate 98%(HPLC) 1g $36 2026-06-04 Buy
AK Scientific J10294 Doxazosin mesylate 99%(HPLC),powder 1g $68 2026-06-04 Buy

Properties

Melting point :275-277°C
storage temp. :2-8°C
solubility :Slightly soluble in water, soluble in a mixture of 15 volumes of water and 35 volumes of tetrahydrofuran, slightly soluble in methanol, practically insoluble in acetone. It shows polymorphism (5.9), some forms may be hygroscopic
form :powder
color :white
BCS Class :1
Stability :Protect from light
InChIKey :VJECBOKJABCYMF-UHFFFAOYSA-N
SMILES :S(O)(=O)(=O)C.NC1=NC(N2CCN(C(C3COC4C=CC=CC=4O3)=O)CC2)=NC2=CC(OC)=C(OC)C=C12
CAS DataBase Reference :77883-43-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): Health Hazard (GHS08)Environment (GHS09)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P314 Get medical advice/attention if you feel unwell.
P501 Dispose of contents/container to..…

Description

Doxazosin mesylate is a quinazoline compound that is a selective inhibitor of the alpha1 subtype of alpha adrenergic receptors. The chemical name of doxazosin mesylate is 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl) piperazine methanesulfonate.The empirical formula for doxazosin mesylate is C23H25N505 • CH4O3S and the molecular weight is 547.6.
Doxazosin mesylate is freely soluble in dimethylsulfoxide, soluble in dimethylformamide, slightly soluble in methanol, ethanol, and water (0.8% at 25°C), and very slightly soluble in acetone and methylene chloride. Each doxazosin mesylate tablet, for oral administration, contains 1 mg, 2 mg, 4 mg and 8 mg of doxazosin as the free base.
Doxazosin mesylate is a new generation of quinazolone α1 receptor blocker developed by the Pfizer company (United States), It has a long half-life, exerting its effects of dilating the blood vessels, reducing the vascular resistance and lowering the blood pressure through blocking the a 1 receptor. It selectively blocks the a1 adrenergic receptor of the prostate smooth muscle matrix, capsule and bladder neck, alleviating the symptoms of patients of benign prostatic hyperplasia, while having good curing effect on the dysuria caused by simple prostatic hyperplasia. In 1988, doxazosin, as a drug for the treatment of hypertension, had been listed in Denmark. In 1995, the US FDA had approved it for the treatment of benign prostatic hyperplasia. In 2002 September, Doxazosin controlled release tablets had been listed in China, providing a new option for the domestic treatment of benign prostatic hyperplasia. It has been recommended abroad as first-line clinical drugs of anti-hypertension and treatment of prostate disease.

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