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ChemicalBook >> CAS DataBase List >> β-Estradiol

β-Estradiol

β-Estradiol price.
  • $11 - $4200
  • Product name: β-Estradiol
  • CAS: 50-28-2
  • MF: C18H24O2
  • MW: 272.39
  • EINECS:200-023-8
  • MDL Number:MFCD01074033
  • Synonyms:Cimara;Estradot;Estring;á-estradiol;ESTRADIOL,MICRONIZEDPOWDER,USP;Estradiol Base Benzoate & derivatives;Estradiol Solution, 100ppm;17β-Estradiol solution
118 prices
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  • Manufactureraablocks
  • Product numberAA0034QQ
  • Product description(17β)-Estra-1,3,5(10)-triene-3,17-diol 98%
  • Packaging5g
  • Price$16
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0034QQ
  • Product description(17β)-Estra-1,3,5(10)-triene-3,17-diol 98%
  • Packaging1g
  • Price$11
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0034QQ
  • Product description(17β)-Estra-1,3,5(10)-triene-3,17-diol 98%
  • Packaging10g
  • Price$29
  • Updated2026-05-28
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  • ManufacturerAK Scientific
  • Product numberJ93754
  • Product descriptionEstradiol
  • Packaging25g
  • Price$130
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8425
  • Product descriptionEstradiol
  • Packaging1g
  • Price$57
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberA8425
  • Product descriptionEstradiol
  • Packaging1g
  • Price$52
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8425
  • Product descriptionEstradiol
  • Packaging10mM(in1mLDMSO)
  • Price$61
  • Updated2026-05-06
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  • ManufacturerArctom
  • Product numberHY-B0141
  • Product descriptionEstradiol 99.93%
  • Packaging1g
  • Price$63
  • Updated2026-05-25
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  • ManufacturerArctom
  • Product numberHY-B0141
  • Product descriptionEstradiol 99.93%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$57
  • Updated2026-05-25
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  • ManufacturerArctom
  • Product numberHY-B0141
  • Product descriptionEstradiol 99.93%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$57
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-B0141
  • Product descriptionEstradiol 99.93%
  • Packaging500mg
  • Price$53
  • Updated2026-05-25
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  • ManufacturerArctom
  • Product numberHY-B0141
  • Product descriptionEstradiol 99.93%
  • Packaging500mg
  • Price$53
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-B0141
  • Product descriptionEstradiol 99.93%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$55
  • Updated2026-05-25
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  • ManufacturerArctom
  • Product numberHY-B0141
  • Product descriptionEstradiol 99.93%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$55
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-B0141R
  • Product descriptionEstradiol (Standard) 99.98%
  • Packaging25mg
  • Price$34
  • Updated2026-05-25
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  • ManufacturerArctom
  • Product numberHY-B0141R
  • Product descriptionEstradiol (Standard) 99.98%
  • Packaging25mg
  • Price$34
  • Updated2026-05-26
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0034QQ (17β)-Estra-1,3,5(10)-triene-3,17-diol 98% 5g $16 2026-05-28 Buy
aablocks AA0034QQ (17β)-Estra-1,3,5(10)-triene-3,17-diol 98% 1g $11 2026-05-28 Buy
aablocks AA0034QQ (17β)-Estra-1,3,5(10)-triene-3,17-diol 98% 10g $29 2026-05-28 Buy
AK Scientific J93754 Estradiol 25g $130 2021-12-16 Buy
ApexBio Technology A8425 Estradiol 1g $57 2026-05-06 Buy
ApexBio Technology A8425 Estradiol 1g $52 2021-12-16 Buy
ApexBio Technology A8425 Estradiol 10mM(in1mLDMSO) $61 2026-05-06 Buy
Arctom HY-B0141 Estradiol 99.93% 1g $63 2026-05-25 Buy
Arctom HY-B0141 Estradiol 99.93% 10mM*1mLinDMSO(Solution) $57 2026-05-25 Buy
Arctom HY-B0141 Estradiol 99.93% 10mM*1mLinDMSO(Solution) $57 2026-05-26 Buy
Arctom HY-B0141 Estradiol 99.93% 500mg $53 2026-05-25 Buy
Arctom HY-B0141 Estradiol 99.93% 500mg $53 2026-05-26 Buy
Arctom HY-B0141 Estradiol 99.93% 10mM*1mLinDMSO(Solid+Solvent) $55 2026-05-25 Buy
Arctom HY-B0141 Estradiol 99.93% 10mM*1mLinDMSO(Solid+Solvent) $55 2026-05-26 Buy
Arctom HY-B0141R Estradiol (Standard) 99.98% 25mg $34 2026-05-25 Buy
Arctom HY-B0141R Estradiol (Standard) 99.98% 25mg $34 2026-05-26 Buy

Properties

Melting point :178-179 °C(lit.)
Boiling point :355.44°C (rough estimate)
alpha :D25 +76 to +83° (dioxane)
Density :1.0708 (rough estimate)
refractive index :80.4 ° (C=1, Dioxane)
Flash point :2℃
storage temp. :room temp
solubility :Practically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent), slightly soluble in methylene chloride.
form :powder
pka :pKa 10.71±0.02(H2O(0.1% p-dioxane) t=25±0.1 I=0.03(KCl))(Approximate)
color :White to off-white
biological source :synthetic (organic)
Water Solubility :Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils.
Merck :14,3703
BRN :1914275
Henry's Law Constant :2.7×105 mol/(m3Pa) at 25℃, HSDB (2015)
BCS Class :1
Stability :Stable. Incompatible with strong oxidizing agents.
Cosmetics Ingredients Functions :SKIN CONDITIONING
InChI :1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
InChIKey :VOXZDWNPVJITMN-ZBRFXRBCSA-N
SMILES :O[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(O)=CC=C4[C@@]3([H])CC[C@@]21C
CAS DataBase Reference :50-28-2(CAS DataBase Reference)
NIST Chemistry Reference :Estra-1,3,5(10)-triene-3,17beta-diol(50-28-2)
EPA Substance Registry System :Estradiol (50-28-2)

Safety Information

Symbol(GHS): Health Hazard (GHS08)Environment (GHS09)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H362 May cause harm to breast-fed children Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy/while nursing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P273 Avoid release to the environment.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

β-Estradiol is the major estrogen secreted by the premenopausal ovary. It acts as an estrogenic hormone receptor (ER) agonist and activator of PI 3-kinase. Further, it is used in the treatment of infertility in women, prostate cancer and breast cancer. It is also employed as an agent of stimulating female puberty induction, as in the treatment of delayed puberty caused by hypogonadism or Turner's syndrome. In addition to this, it is used as part of the hormone replacement therapy for transgender women.

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