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ChemicalBook >> CAS DataBase List >> Flumazenil

Flumazenil

Flumazenil price.
  • $12 - $2113.8
  • Product name: Flumazenil
  • CAS: 78755-81-4
  • MF: C15H14FN3O3
  • MW: 303.29
  • EINECS:616-650-9
  • MDL Number:MFCD00242764
  • Synonyms:FluMenazil;Ro 15-1788/000;Ro 1722;Ro 41-8157;FluMazenil API;FluMazenil(Ro 15-1788);ethyl 12-fluoro-8-Methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14),3,5,10,12-pentaene-5-carboxylate;Ethyl 8-fluoro-5-methyl-5,6-dihydro-6-oxo-4H-imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylate
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  • 10mM*1mLinDMSO(Solid+Solvent)
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  • Manufactureraablocks
  • Product numberAA005JC9
  • Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95%
  • Packaging1mg
  • Price$12
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005JC9
  • Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95%
  • Packaging5mg
  • Price$19
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005JC9
  • Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95%
  • Packaging10mg
  • Price$25
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005JC9
  • Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95%
  • Packaging50mg
  • Price$37
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005JC9
  • Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95%
  • Packaging100mg
  • Price$57
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005JC9
  • Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 98%
  • Packaging250mg
  • Price$79
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005JC9
  • Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 98%
  • Packaging1g
  • Price$196
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005JC9
  • Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 98%
  • Packaging5g
  • Price$874
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberY226294
  • Product descriptionFlumazenil 97.00%
  • Packaging5G
  • Price$1340
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberY226294
  • Product descriptionFlumazenil 97.00%
  • Packaging1G
  • Price$385
  • Updated2026-05-27
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  • ManufacturerAHH
  • Product numberMT-51819
  • Product descriptionFlumazenil 98%
  • Packaging0.5g
  • Price$530
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberMT-51819
  • Product descriptionFlumazenil 97%
  • Packaging0.5g
  • Price$530
  • Updated2026-05-25
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  • ManufacturerAHH
  • Product numberMT-51819
  • Product descriptionFlumazenil 97%
  • Packaging0.5g
  • Price$530
  • Updated2026-05-26
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  • ManufacturerAK Scientific
  • Product numberJ99861
  • Product descriptionFlumazenil
  • Packaging5g
  • Price$1200
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ99861
  • Product descriptionFlumazenil
  • Packaging250mg
  • Price$127
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA423241
  • Product descriptionFlumazenil 95+%
  • Packaging1g
  • Price$224
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA005JC9 Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95% 1mg $12 2026-05-28 Buy
aablocks AA005JC9 Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95% 5mg $19 2026-05-28 Buy
aablocks AA005JC9 Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95% 10mg $25 2026-05-28 Buy
aablocks AA005JC9 Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95% 50mg $37 2026-05-28 Buy
aablocks AA005JC9 Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95% 100mg $57 2026-05-28 Buy
aablocks AA005JC9 Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 98% 250mg $79 2026-05-28 Buy
aablocks AA005JC9 Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 98% 1g $196 2026-05-28 Buy
aablocks AA005JC9 Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 98% 5g $874 2026-05-28 Buy
ACHEMBLOCK Y226294 Flumazenil 97.00% 5G $1340 2026-05-27 Buy
ACHEMBLOCK Y226294 Flumazenil 97.00% 1G $385 2026-05-27 Buy
AHH MT-51819 Flumazenil 98% 0.5g $530 2021-12-16 Buy
AHH MT-51819 Flumazenil 97% 0.5g $530 2026-05-25 Buy
AHH MT-51819 Flumazenil 97% 0.5g $530 2026-05-26 Buy
AK Scientific J99861 Flumazenil 5g $1200 2021-12-16 Buy
AK Scientific J99861 Flumazenil 250mg $127 2021-12-16 Buy
Ambeed A423241 Flumazenil 95+% 1g $224 2021-12-16 Buy

Properties

Melting point :201-203°C
Boiling point :528.0±50.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in DMSO to 25mM
pka :0.86±0.20(Predicted)
form :solid
color :white
Water Solubility :128 mg/L
Merck :14,4135
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Major Application :pharmaceutical (small molecule)
InChI :InChI=1S/C15H14FN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3
InChIKey :OFBIFZUFASYYRE-UHFFFAOYSA-N
SMILES :N12C=NC(C(OCC)=O)=C1CN(C)C(=O)C1=CC(F)=CC=C12
CAS DataBase Reference :78755-81-4(CAS DataBase Reference)
NIST Chemistry Reference :Flumazenil(78755-81-4)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
Precautionary statements:
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P403 Store in a well-ventilated place.

Description

Flumazenil is an imidazobenzodiazepine derivative that competitively inhibits benzodiazepine binding to GABAA receptors with an IC50 value of 2 nM. Flumazenil is non-selective for α1, α2, α3, or α5 subunit-containing GABAA receptors and antagonizes the actions of benzodiazepines on the central nervous system without producing the behavioral or neurological effects typical of the benzodiazepines. Flumazenil has been used to reverse sedation induced by benzodiazepine drugs and has been found to be effective in the treatment of benzodiazepine overdose or withdrawal.

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