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ChemicalBook >> CAS DataBase List >> Fosaprepitant dimeglumine

Fosaprepitant dimeglumine

Fosaprepitant dimeglumine price.
  • $5 - $80099
  • Product name: Fosaprepitant dimeglumine
  • CAS: 265121-04-8
  • MF: C30H39F7N5O11P
  • MW: 809.63
  • EINECS:682-419-4
  • MDL Number:MFCD23102059
  • Synonyms:Phosphonic acid, (3-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)methyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)-, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:2);Unii-D35fm8T64x;[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-Morpholinyl]Methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(MethylaMino)-D-glucitol;1-Deoxy-1-(MethylaMino)-D-glucitol [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-Morpholinyl]Methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate;1-DEOXY-1-(METHYLAMINO)-D-GLUCITOL [[(2R,3S]-2-[(1R)-1-[3,5-BIS (TRIFLUOROMETHYL)PHENYL] PHENYL]ETHOXY]-(4-FLUOROPHENYL);3-[2(R)-[1(R)-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)Morpholin-4-ylMethyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-phosphinic acid bis(N-Methyl-D-glucaMine) salt;Fosaprepitant dimeglumine, >=99%;Fosaprepitant dimegluminer
90 prices
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  • Sigma-Aldrich
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Package
  • 10mM(in1mLDMSO)
  • 1mg
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  • 10mM*1mLinDMSO
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  • Manufactureraablocks
  • Product numberAA00BF0O
  • Product descriptionFosaprepitant dimeglumine 98%(HNMR)
  • Packaging5mg
  • Price$10
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00BF0O
  • Product descriptionFosaprepitant dimeglumine 98%(HNMR)
  • Packaging50mg
  • Price$21
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00BF0O
  • Product descriptionFosaprepitant dimeglumine 98%(HNMR)
  • Packaging100mg
  • Price$29
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00BF0O
  • Product descriptionFosaprepitant dimeglumine 98%
  • Packaging250mg
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  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00BF0O
  • Product descriptionFosaprepitant dimeglumine 98%(HNMR)
  • Packaging1g
  • Price$121
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberZ238363
  • Product descriptionFosaprepitant dimeglumine 98%
  • Packaging1G
  • Price$150
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberZ238363
  • Product descriptionFosaprepitant dimeglumine 98%
  • Packaging5G
  • Price$525
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product numberX3475
  • Product descriptionFosaprepitant dimeglumine 98%(HPLC)
  • Packaging10g
  • Price$720
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberX3475
  • Product descriptionFosaprepitant dimeglumine 98%(HPLC)
  • Packaging1g
  • Price$125
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ11396
  • Product descriptionFosaprepitantdimeglumine
  • Packaging10mg
  • Price$226
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberX3475
  • Product descriptionFosaprepitant dimeglumine 98%(HPLC)
  • Packaging5g
  • Price$420
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberX3475
  • Product descriptionFosaprepitant dimeglumine 98%(HPLC)
  • Packaging250mg
  • Price$46
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ11396
  • Product descriptionFosaprepitant dimeglumine 98%(HPLC)
  • Packaging25mg
  • Price$28
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ11396
  • Product descriptionFosaprepitant dimeglumine 98%(HPLC)
  • Packaging5mg
  • Price$22
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ11396
  • Product descriptionFosaprepitant dimeglumine 98%(HPLC)
  • Packaging100mg
  • Price$68
  • Updated2026-06-04
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  • ManufacturerAmbeed
  • Product numberA455841
  • Product descriptionFosaprepitantdimeglumine 98+%
  • Packaging100mg
  • Price$28
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00BF0O Fosaprepitant dimeglumine 98%(HNMR) 5mg $10 2026-05-28 Buy
aablocks AA00BF0O Fosaprepitant dimeglumine 98%(HNMR) 50mg $21 2026-05-28 Buy
aablocks AA00BF0O Fosaprepitant dimeglumine 98%(HNMR) 100mg $29 2026-05-28 Buy
aablocks AA00BF0O Fosaprepitant dimeglumine 98% 250mg $44 2026-05-28 Buy
aablocks AA00BF0O Fosaprepitant dimeglumine 98%(HNMR) 1g $121 2026-05-28 Buy
ACHEMBLOCK Z238363 Fosaprepitant dimeglumine 98% 1G $150 2026-05-27 Buy
ACHEMBLOCK Z238363 Fosaprepitant dimeglumine 98% 5G $525 2026-05-27 Buy
AK Scientific X3475 Fosaprepitant dimeglumine 98%(HPLC) 10g $720 2026-06-04 Buy
AK Scientific X3475 Fosaprepitant dimeglumine 98%(HPLC) 1g $125 2026-06-04 Buy
AK Scientific J11396 Fosaprepitantdimeglumine 10mg $226 2021-12-16 Buy
AK Scientific X3475 Fosaprepitant dimeglumine 98%(HPLC) 5g $420 2026-06-04 Buy
AK Scientific X3475 Fosaprepitant dimeglumine 98%(HPLC) 250mg $46 2026-06-04 Buy
AK Scientific J11396 Fosaprepitant dimeglumine 98%(HPLC) 25mg $28 2026-06-04 Buy
AK Scientific J11396 Fosaprepitant dimeglumine 98%(HPLC) 5mg $22 2026-06-04 Buy
AK Scientific J11396 Fosaprepitant dimeglumine 98%(HPLC) 100mg $68 2026-06-04 Buy
Ambeed A455841 Fosaprepitantdimeglumine 98+% 100mg $28 2021-12-16 Buy

Properties

storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :≥50.24 mg/mL in DMSO; insoluble in EtOH; ≥13.16 mg/mL in H2O with ultrasonic
form :Powder
pka :Fosaprepitant dimeglumine has four functional groups which have pKa values of 3.05 ± 0.03, 4.92 ± 0.02, 9.67 ± 0.01 and 10.59 ± 0.03. The pka value of 3.05 corresponds to the morpholinium group, the pka of 4.92 corresponds to the monophosphonate group, the pka of 9.67 corresponds to the meglumine counter ion, and the pka of 10.59 corresponds to the triazolinone NH group.
color :White to off-white
optical activity :[α]/D +27 to +34°, c =0.5 in methanol
Water Solubility :H2O: 2mg/mL, clear
InChIKey :UGJUJYSRBQWCEK-QBRZKSSTNA-N
SMILES :FC1=CC=C([C@@H]2N(CCO[C@@H]2O[C@@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)CC(NC4=O)=NN4P(O)(O)=O)C=C1.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Fosaprepitant dimeglumine is a water-soluble prodrug form of the neurokinin-1 receptor antagonist aprepitant. Formulations containing fosaprepitant dimeglumine have been used to prevent chemotherapy-induced nausea and vomiting.

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