GSK-CXCR2
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- $53 - $2500
- Product name: GSK-CXCR2
- CAS: 211096-49-0
- MF: C14H9BrN6O
- MW: 357.16
- EINECS:
- MDL Number:MFCD09971124
- Synonyms:GSK-CXCR2;N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-yl)urea;SB 265610;1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d] [1,2,3]triazol-7-yl)urea;Urea, N-(2-bromophenyl)-N'-(4-cyano-1H-benzotriazol-7-yl)-;SB265610 >=98% (HPLC);CXCR,nonpeptide,inhibit,Inhibitor,SB-265610,inflammation,recruitment,Delay,SB 265610,healing,neutrophil,SB265610,wound,CXC chemokine receptors;SB-265610, 10 mM in DMSO
70 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Alichem
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 1mg
- 5mg
- 10
- 10mg
- 1
- 25mg
- 50mg
- 100MG
- 250mg
- 500mg
- 1g
- 5g
- Manufactureraablocks
- Product numberAA002L2O
- Product descriptionSB 265610 99%
- Packaging1mg
- Price$53
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002L2O
- Product descriptionSB 265610 99%
- Packaging5mg
- Price$68
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002L2O
- Product descriptionSB 265610 99%
- Packaging10mg
- Price$87
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002L2O
- Product descriptionSB 265610 99%
- Packaging25mg
- Price$113
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002L2O
- Product descriptionSB 265610 99%
- Packaging50mg
- Price$192
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002L2O
- Product descriptionSB 265610 99
- Packaging500mg
- Price$1404
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY230337
- Product descriptionSB-265610 98%
- Packaging100MG
- Price$395
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY230337
- Product descriptionSB-265610 98%
- Packaging50MG
- Price$235
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY230337
- Product descriptionSB-265610 98%
- Packaging25MG
- Price$140
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3699BB
- Product descriptionN-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-YL)urea
- Packaging1mg
- Price$206
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3699BB
- Product descriptionN-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-YL)urea
- Packaging10mg
- Price$345
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number211096490
- Product description1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d][1,2,3]triazol-7-yl)urea
- Packaging1g
- Price$929.5
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number211096490
- Product description1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d][1,2,3]triazol-7-yl)urea
- Packaging5g
- Price$2207.7
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001078
- Product descriptionSB-265610 95.00%
- Packaging1MG
- Price$617.3
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5333
- Product descriptionSB265610
- Packaging10mg
- Price$252
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5333
- Product descriptionSB 265610
- Packaging10mg
- Price$330
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA002L2O | SB 265610 99% | 1mg | $53 | 2026-05-28 | Buy |
| aablocks | AA002L2O | SB 265610 99% | 5mg | $68 | 2026-05-28 | Buy |
| aablocks | AA002L2O | SB 265610 99% | 10mg | $87 | 2026-05-28 | Buy |
| aablocks | AA002L2O | SB 265610 99% | 25mg | $113 | 2026-05-28 | Buy |
| aablocks | AA002L2O | SB 265610 99% | 50mg | $192 | 2026-05-28 | Buy |
| aablocks | AA002L2O | SB 265610 99 | 500mg | $1404 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y230337 | SB-265610 98% | 100MG | $395 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y230337 | SB-265610 98% | 50MG | $235 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y230337 | SB-265610 98% | 25MG | $140 | 2026-05-27 | Buy |
| AK Scientific | 3699BB | N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-YL)urea | 1mg | $206 | 2021-12-16 | Buy |
| AK Scientific | 3699BB | N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-YL)urea | 10mg | $345 | 2021-12-16 | Buy |
| Alichem | 211096490 | 1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d][1,2,3]triazol-7-yl)urea | 1g | $929.5 | 2021-12-16 | Buy |
| Alichem | 211096490 | 1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d][1,2,3]triazol-7-yl)urea | 5g | $2207.7 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001078 | SB-265610 95.00% | 1MG | $617.3 | 2021-12-16 | Buy |
| ApexBio Technology | B5333 | SB265610 | 10mg | $252 | 2021-12-16 | Buy |
| ApexBio Technology | B5333 | SB 265610 | 10mg | $330 | 2026-05-06 | Buy |
Properties
Boiling point :527.0±45.0 °C(Predicted)
Density :1.77±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL, clear
pka :6.13±0.40(Predicted)
form :powder
color :white to light brown
InChI :1S/C14H9BrN6O/c15-9-3-1-2-4-10(9)17-14(22)18-11-6-5-8(7-16)12-13(11)20-21-19-12/h1-6H,(H2,17,18,22)(H,19,20,21)
InChIKey :SEDUMQWZEOMXSO-UHFFFAOYSA-N
SMILES :Brc1ccccc1NC(=O)Nc2ccc(C#N)c3nn[nH]c23
Density :1.77±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL, clear
pka :6.13±0.40(Predicted)
form :powder
color :white to light brown
InChI :1S/C14H9BrN6O/c15-9-3-1-2-4-10(9)17-14(22)18-11-6-5-8(7-16)12-13(11)20-21-19-12/h1-6H,(H2,17,18,22)(H,19,20,21)
InChIKey :SEDUMQWZEOMXSO-UHFFFAOYSA-N
SMILES :Brc1ccccc1NC(=O)Nc2ccc(C#N)c3nn[nH]c23
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
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Description
CXCR2 (IL-8RB) is a seven-transmembrane G protein-coupled receptor whose physiological ligands include IL-8 (CXCL8) and many other CXC chemokines involved in the trafficking and activation of inflammatory cells. It is involved in various inflammatory diseases, including chronic obstructive pulmonary disease, psoriasis, rheumatoid arthritis, and ulcerative colitis. SB 265610 is a nonpeptide, allosteric, inverse agonist of CXCR2 (Kd = 2.51 nM) that prevents receptor activation by binding to a region distinct from the agonist binding site. It does not bind to the related CXCR1 receptor. It has been shown to prevent neutrophil chemotaxis both in vitro and in a rat model of hyperoxia-induced lung injury.More related product prices
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