GSK5959
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- $32 - $7569.7
- Product name: GSK5959
- CAS: 901245-65-6
- MF: C22H26N4O3
- MW: 394.47
- EINECS:
- MDL Number:MFCD14744183
- Synonyms:GSK5959;Benzamide, N-[2,3-dihydro-1,3-dimethyl-2-oxo-6-(1-piperidinyl)-1H-benzimidazol-5-yl]-2-methoxy-;CS-1636;GSK-5959;GSK5959;N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-piperidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide;BRPF1-IN-3;BRPF3,GSK5959,bromodomain,Inhibitor,inhibit,BRD1,BRPF1,Epigenetic Reader Domain,GSK-5959,GSK 5959,BRPF2,epigenetics;N-(1,3-dimethyl-2-oxo-6-(piperidin-1-yl)-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-2-methoxybenzamide
51 prices
Selected condition：
Brand
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- Axon Medchem
- Biosynth
- BroadPharm
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
- TRC
- Usbiological
Package
- 250mg
- 0.5g
- 10mM*1mLinDMSO(Solution)
- 50
- 10
- 1g
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 5mg
- 10mg
- 25MG
- 50mg
- 100MG
- ManufacturerACHEMBLOCK
- Product numberY226997
- Product descriptionGSK-5959 97.00%
- Packaging25MG
- Price$105
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY226997
- Product descriptionGSK-5959 97.00%
- Packaging100MG
- Price$305
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number1994CW
- Product descriptionCID15990224
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1994CW
- Product descriptionCID15990224
- Packaging5mg
- Price$209
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1994CW
- Product descriptionCID15990224
- Packaging10mg
- Price$302
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4916
- Product descriptionGSK5959
- Packaging50mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4916
- Product descriptionGSK 5959
- Packaging50mg
- Price$450
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4916
- Product descriptionGSK5959
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4916
- Product descriptionGSK 5959
- Packaging10mg
- Price$150
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-18665
- Product descriptionGSK-5959 99.73%
- Packaging10mg
- Price$105
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-18665
- Product descriptionGSK-5959 99.73%
- Packaging5mg
- Price$63
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-18665
- Product descriptionGSK-5959 99.73%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$65
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-18665
- Product descriptionGSK-5959 99.73%
- Packaging10mM*1mLinDMSO(Solution)
- Price$69
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-18665
- Product descriptionGSK-5959 99.73%
- Packaging50mg
- Price$304
- Updated2026-05-26
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2410
- Product descriptionGSK 5959
- Packaging10mg
- Price$148.5
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2410
- Product descriptionGSK 5959
- Packaging50mg
- Price$588.5
- Updated2026-05-19
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | Y226997 | GSK-5959 97.00% | 25MG | $105 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y226997 | GSK-5959 97.00% | 100MG | $305 | 2026-05-27 | Buy |
| AK Scientific | 1994CW | CID15990224 | 1mg | $133 | 2021-12-16 | Buy |
| AK Scientific | 1994CW | CID15990224 | 5mg | $209 | 2021-12-16 | Buy |
| AK Scientific | 1994CW | CID15990224 | 10mg | $302 | 2021-12-16 | Buy |
| ApexBio Technology | B4916 | GSK5959 | 50mg | $450 | 2021-12-16 | Buy |
| ApexBio Technology | B4916 | GSK 5959 | 50mg | $450 | 2026-05-06 | Buy |
| ApexBio Technology | B4916 | GSK5959 | 10mg | $150 | 2021-12-16 | Buy |
| ApexBio Technology | B4916 | GSK 5959 | 10mg | $150 | 2026-05-06 | Buy |
| Arctom | HY-18665 | GSK-5959 99.73% | 10mg | $105 | 2026-05-26 | Buy |
| Arctom | HY-18665 | GSK-5959 99.73% | 5mg | $63 | 2026-05-26 | Buy |
| Arctom | HY-18665 | GSK-5959 99.73% | 10mM*1mLinDMSO(Solid+Solvent) | $65 | 2026-05-26 | Buy |
| Arctom | HY-18665 | GSK-5959 99.73% | 10mM*1mLinDMSO(Solution) | $69 | 2026-05-26 | Buy |
| Arctom | HY-18665 | GSK-5959 99.73% | 50mg | $304 | 2026-05-26 | Buy |
| Axon Medchem | Axon2410 | GSK 5959 | 10mg | $148.5 | 2026-05-19 | Buy |
| Axon Medchem | Axon2410 | GSK 5959 | 50mg | $588.5 | 2026-05-19 | Buy |
Properties
Boiling point :527.3±50.0 °C(Predicted)
Density :1.263±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : 13 mg/mL (32.96 mM; Need ultrasonic and warming)
form :Powder
pka :13.06±0.20(Predicted)
color :Light yellow to yellow
Density :1.263±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : 13 mg/mL (32.96 mM; Need ultrasonic and warming)
form :Powder
pka :13.06±0.20(Predicted)
color :Light yellow to yellow
Safety Information
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Description
The bromodomain and PHD finger-containing (BRPF) proteins are scaffolding components of chromatin-binding MOZ/MORF histone acetyltransferase complexes, which have activity as transcriptional regulators. BRPF1 (BR140 or Peregrin) is important for maintaining Hox gene expression and the development of multiple tissues, axial skeleton, and the hematopoietic system. GSK5959 is a potent, cell-permeable inhibitor of the BRPF1 bromodomain (IC50 = 80 nM). It exhibits greater than 100-fold selectivity for the BRPF1 bromodomain over a panel of 35 other bromodomains. GSK5959 disrupts chromatin binding of BRPF1 in a cellular assay by blocking the interaction of BRPF1 with histone H3.3.More related product prices
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