Gemfibrozil
|
- $5 - $2055.9
- Product name: Gemfibrozil
- CAS: 25812-30-0
- MF: C15H22O3
- MW: 250.33
- EINECS:247-280-2
- MDL Number:MFCD00079335
- Synonyms:PENTANOIC ACID, 5-(2,5-DIMETHYLPHENOXY)-2,2-DIMETHYL-;5-(2,5-DIMETHYLPHYLPHENOXY)-2,2-DIMETHYLPENTANOIC ACID;5-(2,5-DIMETHYL-PHENOXY)-2,2-DIMETHYL-PENTANOIC ACID;2,2-DIMETHYL-5-[2,5-DIMETHYL-PHENOXY]PENTANOIC ACID;2,2-DIMETHYL-5-(2,5-XYLYLOXY) VALERIC ACID;GEMFIBROZIL;Gemcitabine intermediates;5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic Acid, CI-719, Decrelip, Genlip, Gevilon, Lipozid, Lpur, Lopid
114 prices
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Brand
- aablocks
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Aronis compounds
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 50μg
- 100μg
- 500μg
- 1mg
- 25mg
- 1mlx10mM(inDMSO)
- 10mg
- y0000513
- 50mg
- 100mg
- 200mg
- 500mg
- 1g
- 250mg
- y0000514
- 5g
- 10g
- 25.00g
- 25g
- 50g
- 100g
- 100.00g
- 250g
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM(in1mLDMSO)
- 10mM*1mLinDMSO(Solution)
- 5 mg
- 196 μg
- 500.00g
- 500g
- 2000g
- 10mM(in 1mL DMSO)
- 1000g
- Manufactureraablocks
- Product numberAA0034VZ
- Product description5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid ≥99%
- Packaging1g
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0034VZ
- Product description5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid ≥99%
- Packaging5g
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0034VZ
- Product description5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid ≥99%
- Packaging10g
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0034VZ
- Product description5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid 98%
- Packaging25g
- Price$23
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0034VZ
- Product description5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid 98%
- Packaging100g
- Price$56
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0034VZ
- Product description5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid 98%
- Packaging500g
- Price$206
- Updated2026-05-28
- Buy
- ManufacturerAHH
- Product numberAPI-1649
- Product descriptionGemfibrozil 98%
- Packaging1000g
- Price$490
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberAPI-1649
- Product descriptionGemfibrozil 97%
- Packaging1000g
- Price$490
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberJ10068
- Product descriptionGemfibrozil >98%(GC),powder
- Packaging1g
- Price$195
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberH900
- Product descriptionGemfibrozil 98%(HPLC)
- Packaging25g
- Price$39
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ10068
- Product descriptionGemfibrozil >98%(GC),powder
- Packaging25mg
- Price$42
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ93003
- Product description2,2-Dimethyl-5-(2,5-dimethylphenoxy)pentanoic acid 95%
- Packaging25g
- Price$27
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberH900
- Product descriptionGemfibrozil 98%(HPLC)
- Packaging5g
- Price$18
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ93003
- Product description2,2-Dimethyl-5-(2,5-dimethylphenoxy)pentanoic acid 95%
- Packaging5g
- Price$13
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberH900
- Product descriptionGemfibrozil
- Packaging25g
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ93003
- Product description2,2-Dimethyl-5-(2,5-dimethylphenoxy)pentanoic acid 95%
- Packaging100g
- Price$71
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0034VZ | 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid ≥99% | 1g | $10 | 2026-05-28 | Buy |
| aablocks | AA0034VZ | 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid ≥99% | 5g | $12 | 2026-05-28 | Buy |
| aablocks | AA0034VZ | 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid ≥99% | 10g | $16 | 2026-05-28 | Buy |
| aablocks | AA0034VZ | 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid 98% | 25g | $23 | 2026-05-28 | Buy |
| aablocks | AA0034VZ | 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid 98% | 100g | $56 | 2026-05-28 | Buy |
| aablocks | AA0034VZ | 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid 98% | 500g | $206 | 2026-05-28 | Buy |
| AHH | API-1649 | Gemfibrozil 98% | 1000g | $490 | 2021-12-16 | Buy |
| AHH | API-1649 | Gemfibrozil 97% | 1000g | $490 | 2026-05-26 | Buy |
| AK Scientific | J10068 | Gemfibrozil >98%(GC),powder | 1g | $195 | 2026-06-04 | Buy |
| AK Scientific | H900 | Gemfibrozil 98%(HPLC) | 25g | $39 | 2026-06-04 | Buy |
| AK Scientific | J10068 | Gemfibrozil >98%(GC),powder | 25mg | $42 | 2026-06-04 | Buy |
| AK Scientific | J93003 | 2,2-Dimethyl-5-(2,5-dimethylphenoxy)pentanoic acid 95% | 25g | $27 | 2026-06-04 | Buy |
| AK Scientific | H900 | Gemfibrozil 98%(HPLC) | 5g | $18 | 2026-06-04 | Buy |
| AK Scientific | J93003 | 2,2-Dimethyl-5-(2,5-dimethylphenoxy)pentanoic acid 95% | 5g | $13 | 2026-06-04 | Buy |
| AK Scientific | H900 | Gemfibrozil | 25g | $70 | 2021-12-16 | Buy |
| AK Scientific | J93003 | 2,2-Dimethyl-5-(2,5-dimethylphenoxy)pentanoic acid 95% | 100g | $71 | 2026-06-04 | Buy |
Properties
Melting point :61-63°C
Boiling point :158-159 C
Density :1.1109 (rough estimate)
refractive index :1.5020 (estimate)
storage temp. :2-8°C
solubility :Practically insoluble in water, very soluble in methylene chloride, freely soluble in anhydrous ethanol and in methanol.
form :powder
pka :4.75±0.45(Predicted)
color :White to Off-White
Water Solubility :>0.5g/L(temperature not stated)
Merck :14,4388
BCS Class :2
Major Application :forensics and toxicology
pharmaceutical (small molecule) InChI :1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17)
InChIKey :HEMJJKBWTPKOJG-UHFFFAOYSA-N
SMILES :Cc1ccc(C)c(OCCCC(C)(C)C(O)=O)c1
CAS DataBase Reference :25812-30-0(CAS DataBase Reference)
IARC :3 (Vol. 66) 1996
EPA Substance Registry System :Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl- (25812-30-0)
Boiling point :158-159 C
Density :1.1109 (rough estimate)
refractive index :1.5020 (estimate)
storage temp. :2-8°C
solubility :Practically insoluble in water, very soluble in methylene chloride, freely soluble in anhydrous ethanol and in methanol.
form :powder
pka :4.75±0.45(Predicted)
color :White to Off-White
Water Solubility :>0.5g/L(temperature not stated)
Merck :14,4388
BCS Class :2
Major Application :forensics and toxicology
pharmaceutical (small molecule) InChI :1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17)
InChIKey :HEMJJKBWTPKOJG-UHFFFAOYSA-N
SMILES :Cc1ccc(C)c(OCCCC(C)(C)C(O)=O)c1
CAS DataBase Reference :25812-30-0(CAS DataBase Reference)
IARC :3 (Vol. 66) 1996
EPA Substance Registry System :Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl- (25812-30-0)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Gemfibrozil is a fibrate that activates peroxisome proliferator-activator α (PPARα, EC50 = 193 μM) with 100% efficacy. It also activates PPARγ (EC50 = 148 μM), but with only 79% efficacy. Presumably through its effects on PPARα, gemfibrozil lowers triglycerides and increases high density lipoprotein cholesterol levels and is used in the context of atherogenic dyslipidemia. Gemfibrozil strongly binds liver fatty acid-binding protein (Ki = 1.8 μM). Phase II metabolites of gemfibrozil inhibit certain cytochrome P450 isoforms, increasing drug-drug interaction risks.More related product prices
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