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ChemicalBook >> CAS DataBase List >> Glibenclamide

Glibenclamide

Glibenclamide price.
  • $6 - $1097
  • Product name: Glibenclamide
  • CAS: 10238-21-8
  • MF: C23H28ClN3O5S
  • MW: 494
  • EINECS:233-570-6
  • MDL Number:MFCD00056625
  • Synonyms:LABOTEST-BB LT00244861;GLIBENCLAMIDE;GLYBURIDE USP;GlibenclamideGlibenclamideBp;5-CHLORO-N-[4-(CYCLOHEXYLUREIDOSULFONYL)PHENETHYL]-2-METHOXYBENZAMIDE;5-CHLORO-N-[2-[4-[[[(CYCLOHEXYLAMINO)CARBONYL]AMINO]-SULFONYL]PHENYL]ETHYL]-2-METHOXYBENZAMIDE;adiab ;azuglucon
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  • aablocks
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  • Manufactureraablocks
  • Product numberAA003MLX
  • Product description5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide 98%
  • Packaging1g
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003MLX
  • Product description5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide 98%
  • Packaging5g
  • Price$12
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003MLX
  • Product description5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide 98%
  • Packaging25g
  • Price$15
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003MLX
  • Product description5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide ≥99%
  • Packaging100g
  • Price$46
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003MLX
  • Product description5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide 98%
  • Packaging500g
  • Price$174
  • Updated2026-05-28
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3613-G005
  • Product descriptionGlyburide (USP) ≥98%
  • Packaging5g
  • Price$50
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3613-G010
  • Product descriptionGlyburide(USP) ≥98%
  • Packaging10g
  • Price$80
  • Updated2021-12-16
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3613-G010
  • Product descriptionGlyburide (USP) ≥98%
  • Packaging10g
  • Price$90
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3613-G001
  • Product descriptionGlyburide(USP) ≥98%
  • Packaging1g
  • Price$28
  • Updated2021-12-16
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3613-G001
  • Product descriptionGlyburide (USP) ≥98%
  • Packaging1g
  • Price$28
  • Updated2026-05-06
  • Buy
  • ManufacturerAK Scientific
  • Product numberG621
  • Product descriptionGlibenclamide
  • Packaging500g
  • Price$354
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA212350
  • Product description5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide 98%
  • Packaging25g
  • Price$39
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA212350
  • Product description5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide 98%
  • Packaging1g
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA212350
  • Product description5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide 98%
  • Packaging100g
  • Price$94
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1296
  • Product descriptionGlibenclamide
  • Packaging1g
  • Price$50
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1296
  • Product descriptionGlibenclamide
  • Packaging10mM(in1mLDMSO)
  • Price$55
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003MLX 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide 98% 1g $10 2026-05-28 Buy
aablocks AA003MLX 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide 98% 5g $12 2026-05-28 Buy
aablocks AA003MLX 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide 98% 25g $15 2026-05-28 Buy
aablocks AA003MLX 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide ≥99% 100g $46 2026-05-28 Buy
aablocks AA003MLX 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide 98% 500g $174 2026-05-28 Buy
Adipogen Life Sciences AG-CR1-3613-G005 Glyburide (USP) ≥98% 5g $50 2026-05-06 Buy
Adipogen Life Sciences AG-CR1-3613-G010 Glyburide(USP) ≥98% 10g $80 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3613-G010 Glyburide (USP) ≥98% 10g $90 2026-05-06 Buy
Adipogen Life Sciences AG-CR1-3613-G001 Glyburide(USP) ≥98% 1g $28 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3613-G001 Glyburide (USP) ≥98% 1g $28 2026-05-06 Buy
AK Scientific G621 Glibenclamide 500g $354 2021-12-16 Buy
Ambeed A212350 5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide 98% 25g $39 2021-12-16 Buy
Ambeed A212350 5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide 98% 1g $6 2021-12-16 Buy
Ambeed A212350 5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide 98% 100g $94 2021-12-16 Buy
ApexBio Technology B1296 Glibenclamide 1g $50 2026-05-06 Buy
ApexBio Technology B1296 Glibenclamide 10mM(in1mLDMSO) $55 2026-05-06 Buy

Properties

Melting point :173-175°C
Density :1.1805 (rough estimate)
refractive index :1.6100 (estimate)
storage temp. :2-8°C
solubility :ethanol: soluble2mg/mL
form :White solid
pka :5.3(at 25℃)
color :White
Water Solubility :Soluble in ethanol (5 mg/mL), DMSO (25 mg/mL), chloroform (1:36), methanol (1:250), and DMF. Insoluble in water.
Merck :14,4478
BCS Class :2
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Major Application :pharmaceutical (small molecule)
InChIKey :ZNNLBTZKUZBEKO-UHFFFAOYSA-N
SMILES :COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3
CAS DataBase Reference :10238-21-8(CAS DataBase Reference)
NIST Chemistry Reference :Glyburide(10238-21-8)
EPA Substance Registry System :Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy- (10238-21-8)

Safety Information

Symbol(GHS): Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Glyburide (Glibenclamide) is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+ channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production. Glyburide (Glibenclamide) is an ATP-dependent K+ channel (KIR6, KATP) and CFTR Cl- channel blocker. This compound inhibits recombinant CFTR Cl- channels (IC50 = 20 ?M).

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