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ChemicalBook >> CAS DataBase List >> HIRUDIN

HIRUDIN

HIRUDIN price.
  • $96 - $28732
  • Product name: HIRUDIN
  • CAS: 8001-27-2
  • MF: C287H440N80O113S7
  • MW: 7043.4877
  • EINECS:232-279-1
  • MDL Number:MFCD00081692
  • Synonyms:hirudex ;recombinanthirudin ;HIRUDIN RECOMBINANT;DESULFATO-HIRUDIN;DESULFO-HIRUDIN;NATIVE HIRUDIN;[TYR63]HIRUDIN (HV1), LEECH;(63-tyrosine)hirudin (hv1),leech,rec. F. yeast
22 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Biosynth
  • ChemScene
  • Sigma-Aldrich
Package
  • 2μg
  • 0.002mg
  • 0.01mg
  • 10μg
  • 1mg
  • 5mg
  • 2G
  • 10G
  • 1ea
  • 10units
  • 100units
  • 500??g
  • 500units
  • 2000units
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPEP0011558
  • Product descriptionRECOMBINANT HIRUDIN 95.00%
  • Packaging2G
  • Price$615.14
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPEP0011558
  • Product descriptionRECOMBINANT HIRUDIN 95.00%
  • Packaging10G
  • Price$747.77
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBITP1576
  • Product descriptionRecombinant Hirudin
  • Packaging2μg
  • Price$96
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberBITP1576
  • Product descriptionRecombinant Hirudin
  • Packaging10μg
  • Price$209
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberBITP1576
  • Product descriptionRecombinant Hirudin
  • Packaging1mg
  • Price$3626
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberPRO-362
  • Product descriptionHirudin Recombinant
  • Packaging1mg
  • Price$5104.38
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberXH173313
  • Product descriptionHirudin from leeches
  • Packaging1mg
  • Price$28732
  • Updated2026-06-05
  • Buy
  • ManufacturerBiosynth
  • Product numberPRO-362
  • Product descriptionHirudin Recombinant
  • Packaging0.01mg
  • Price$265.43
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberPRO-362
  • Product descriptionHirudin Recombinant
  • Packaging0.002mg
  • Price$150
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0143010
  • Product descriptionHirudin 95.0%
  • Packaging500??g
  • Price$731
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0143010
  • Product descriptionHirudin 95.0%
  • Packaging500??g
  • Price$731
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0143010
  • Product descriptionHirudin 95.0%
  • Packaging5mg
  • Price$3521
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0143010
  • Product descriptionHirudin 95.0%
  • Packaging5mg
  • Price$3521
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0143010
  • Product descriptionHirudin 95.0%
  • Packaging1mg
  • Price$1170
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0143010
  • Product descriptionHirudin 95.0%
  • Packaging1mg
  • Price$1170
  • Updated2026-06-04
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number94581
  • Product descriptionHirudin recombinant from yeast
  • Packaging1ea
  • Price$1500
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation PEP0011558 RECOMBINANT HIRUDIN 95.00% 2G $615.14 2021-12-16 Buy
American Custom Chemicals Corporation PEP0011558 RECOMBINANT HIRUDIN 95.00% 10G $747.77 2021-12-16 Buy
Apolloscientific BITP1576 Recombinant Hirudin 2μg $96 2026-06-04 Buy
Apolloscientific BITP1576 Recombinant Hirudin 10μg $209 2026-06-04 Buy
Apolloscientific BITP1576 Recombinant Hirudin 1mg $3626 2026-06-04 Buy
Biosynth PRO-362 Hirudin Recombinant 1mg $5104.38 2026-06-04 Buy
Biosynth XH173313 Hirudin from leeches 1mg $28732 2026-06-05 Buy
Biosynth PRO-362 Hirudin Recombinant 0.01mg $265.43 2026-06-04 Buy
Biosynth PRO-362 Hirudin Recombinant 0.002mg $150 2026-06-04 Buy
ChemScene CS-0143010 Hirudin 95.0% 500??g $731 2026-06-04 Buy
ChemScene CS-0143010 Hirudin 95.0% 500??g $731 2026-06-04 Buy
ChemScene CS-0143010 Hirudin 95.0% 5mg $3521 2026-06-04 Buy
ChemScene CS-0143010 Hirudin 95.0% 5mg $3521 2026-06-04 Buy
ChemScene CS-0143010 Hirudin 95.0% 1mg $1170 2026-06-04 Buy
ChemScene CS-0143010 Hirudin 95.0% 1mg $1170 2026-06-04 Buy
Sigma-Aldrich 94581 Hirudin recombinant from yeast 1ea $1500 2026-04-30 Buy

Properties

storage temp. :2-8°C
solubility :0.1 M Tris, 0.2 M NaCl, pH 8.4: 1vial/mL, clear, colorless
form :lyophilized powder
color :white
biological source :synthetic
yeast (Pichia pastoris) Water Solubility :pyridine: soluble
water: soluble Merck :13,4737
Specific Activity :≥7,000ATU/mg protein (ATU = antithrombin units)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Refludan was launched in Germany for heparin-associated thrombocytopenia. Originally isolated from the saliva of leeches (Hirudo medicinalis), the gene for recombinant hirudin was synthesized and expressed in Saccharomyces cerevisiae. The isolated protein is 65 amino acids differing from the native protein by the first two amino acids (Leu1 and Thr2) and Tyr63 is not sulfated, while it does retain the three disulfide bonds. Refludan is a potent, specific and almost irreversible inhibitor of thrombin with which it forms a 1:1 complex. The N-terminal domain binds to the active catalytic site of thrombin, while the C-terminal end binds to the anion binding exosite (fibrinogen binding cleft). It has several advantages over heparin: it can inhibit thrombin bound to extracellular matrices, does not require antithrombin Ⅲ as a cofactor, is not inhibited by activated platelet nor increases platelet activity, and is a pure, single compound with a single mechanism of action. It is useful for myocardial infarcts, unstable angia and cardiovascular events. Heparin treatment can be inhibited by platelets activated by the Fc fragment of antibodies developed to the antigen of heparin-platelet factor 4. A corresponding inactivation of Refuldan is not known.

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