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ChemicalBook >> CAS DataBase List >> Harpagoside

Harpagoside

Harpagoside price.
  • $13 - $1680
  • Product name: Harpagoside
  • CAS: 19210-12-9
  • MF: C24H30O11
  • MW: 494.49
  • EINECS:242-881-6
  • MDL Number:MFCD00017415
  • Synonyms:HARPAGOSIDE;Harpagosid;[1S-[1alpha,4aalpha,5alpha,7alpha(E),7aalpha]]-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[(allyl-1-oxo-3-phenyl)oxy]cyclopenta[c]pyran-1-yl-beta-D-glucopyranoside;[(1S,4aS,5R,7S,7aS)-4a,5-Dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] (E)-3-phenylprop-2-enoate;HARPAGOSIDE WITH HPLC;7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl;β-D-Glucopyranoside, (1S,4aS,5R,7S,7aS)-1,4a,5,6;8-O-E CINNAMOYL HARPAGIDE
99 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • JR MediChem
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 5mg
  • 20mg
  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 10mg
  • y0000673
  • 25mg
  • 50.00mg
  • 50mg
  • 100mg
  • 100.00mg
  • 250mg
  • 250.00mg
  • 500mg
  • 1000mg
  • 1g
  • 1 mg
  • Manufactureraablocks
  • Product numberAA0074G5
  • Product descriptionHarpagoside 99%
  • Packaging1mg
  • Price$13
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0074G5
  • Product descriptionHarpagoside
  • Packaging10mg
  • Price$93
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0074G5
  • Product descriptionHarpagoside ≥98%
  • Packaging25mg
  • Price$122
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0074G5
  • Product descriptionHarpagoside ≥98%
  • Packaging50mg
  • Price$184
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0074G5
  • Product descriptionHarpagoside
  • Packaging100mg
  • Price$317
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0074G5
  • Product descriptionHarpagoside ≥98%
  • Packaging250mg
  • Price$589
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15421
  • Product descriptionHarpagoside 98%
  • Packaging100MG
  • Price$110
  • Updated2026-05-27
  • Buy
  • ManufacturerAHH
  • Product numberMT-52300
  • Product descriptionHarpagoside 98%
  • Packaging1g
  • Price$370
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-52300
  • Product descriptionHarpagoside 97%
  • Packaging1g
  • Price$370
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-52300
  • Product descriptionHarpagoside 97%
  • Packaging1g
  • Price$370
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0696
  • Product descriptionHarpagoside
  • Packaging1g
  • Price$1454
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0696
  • Product descriptionHarpagoside
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0696
  • Product descriptionHarpagoside
  • Packaging10mg
  • Price$128
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0696
  • Product descriptionHarpagoside
  • Packaging25mg
  • Price$177
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA268491
  • Product descriptionHarpagoside 98%
  • Packaging50mg
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA268491
  • Product descriptionHarpagoside 98%
  • Packaging5mg
  • Price$30
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0074G5 Harpagoside 99% 1mg $13 2026-05-28 Buy
aablocks AA0074G5 Harpagoside 10mg $93 2026-05-28 Buy
aablocks AA0074G5 Harpagoside ≥98% 25mg $122 2026-05-28 Buy
aablocks AA0074G5 Harpagoside ≥98% 50mg $184 2026-05-28 Buy
aablocks AA0074G5 Harpagoside 100mg $317 2026-05-28 Buy
aablocks AA0074G5 Harpagoside ≥98% 250mg $589 2026-05-28 Buy
ACHEMBLOCK M15421 Harpagoside 98% 100MG $110 2026-05-27 Buy
AHH MT-52300 Harpagoside 98% 1g $370 2021-12-16 Buy
AHH MT-52300 Harpagoside 97% 1g $370 2026-05-25 Buy
AHH MT-52300 Harpagoside 97% 1g $370 2026-05-26 Buy
AK Scientific V0696 Harpagoside 1g $1454 2021-12-16 Buy
AK Scientific V0696 Harpagoside 5mg $100 2021-12-16 Buy
AK Scientific V0696 Harpagoside 10mg $128 2021-12-16 Buy
AK Scientific V0696 Harpagoside 25mg $177 2021-12-16 Buy
Ambeed A268491 Harpagoside 98% 50mg $149 2021-12-16 Buy
Ambeed A268491 Harpagoside 98% 5mg $30 2021-12-16 Buy

Properties

Melting point :120°C (dec.)
Boiling point :720.7±60.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
pka :11.70±0.70(Predicted)
form :Solid
color :White to Light Yellow
optical activity :[α]/D -50 to -30°
Stability :Hygroscopic
Cosmetics Ingredients Functions :SKIN CONDITIONING
InChIKey :KVRQGMOSZKPBNS-FMHLWDFHSA-N
SMILES :O[C@@]12C=CO[C@@H](O[C@@]3([H])[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)[C@]1([H])[C@@](C)(OC(=O)/C=C/C1C=CC=CC=1)C[C@H]2O |&1:1,5,7,9,10,12,14,19,21,35,r|
LogP :-1.591 (est)
CAS DataBase Reference :19210-12-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Harpagoside is an anti-inflammatory small molecule natural product originally isolated from the Harpagophytum procumbens (Devil’s Claw) root, but can be isolated from other plants such as Crophularia ningpoensis Hemsl (Figwort). Treatment of HepG2 cells with Harpagoside demonstrated suppression of NF-κB nuclear translocation and degradation of IκB-α, blocking NF-κB activation. Multiple anti-inflammatory cellular effects were correlated with this blockade, as Harpagoside was observed to inhibit the expression of inflammation-mediating enzymes cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), and to reduce lipopolysaccharide-induced mRNA levels. The suppression of NF-κB activation is indicated as the mechanism beneath the anti-inflammatory effects of Harpagoside.

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