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ChemicalBook >> CAS DataBase List >> Icatibant Acetate

Icatibant Acetate

Icatibant Acetate price.
  • $72 - $5654.2
  • Product name: Icatibant Acetate
  • CAS: 138614-30-9
  • MF: C59H89N19O13S.C2H4O2
  • MW: 1364.59
  • EINECS:206-141-6
  • MDL Number:MFCD04112967
  • Synonyms:Firazyr;HOE 140 SYNTHETIC >99% SELECTIVE B2 BRAD YKIN;d-arg-l-arg-l-pro-l-hyp-gly-l-(2-thienyl)ala-l-ser-d-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-l-(2α,3β,7aβ)-octahydro-1h-indole-2-carbonyl-l-arg;Icatibant acetate, D-Arg-L-Arg-L-Pro-L-Hyp-Gly-L-(2-thienyl)Ala-L-Ser-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3β,7aβ)-octahydro-1H-indole-2-carbonyl-L-Arg;HOE 140 Acetate;lcatibant Acetate;HOE-140 (Icatibant);HOE140; ICATIBANT;HOE 140
70 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solution)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 250μg
  • 10mM*1mLinDMSO
  • 500μg
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA0018T0
  • Product descriptionL-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (salt)
  • Packaging2mg
  • Price$99
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0018T0
  • Product descriptionL-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (salt)
  • Packaging5mg
  • Price$178
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0018T0
  • Product descriptionL-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (salt) ≥98%
  • Packaging50mg
  • Price$189
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0018T0
  • Product descriptionL-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (salt) ≥98%
  • Packaging100mg
  • Price$324
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0018T0
  • Product descriptionL-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (salt)
  • Packaging1mg
  • Price$72
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0018T0
  • Product descriptionL-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (salt) ≥98%
  • Packaging250mg
  • Price$551
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberZ238474
  • Product descriptionIcatibant Acetate 98%
  • Packaging100MG
  • Price$250
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberZ238474
  • Product descriptionIcatibant Acetate 98%
  • Packaging25MG
  • Price$125
  • Updated2026-05-27
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010072
  • Product descriptionICATIBANT ACETATE 95.00%
  • Packaging1MG
  • Price$525
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010072
  • Product descriptionICATIBANT ACETATE 95.00%
  • Packaging5MG
  • Price$775
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC6403
  • Product descriptionIcatibant Acetate
  • Packaging25mg
  • Price$620
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC6403
  • Product descriptionIcatibant Acetate
  • Packaging1mg
  • Price$90
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC6403
  • Product descriptionIcatibant Acetate
  • Packaging5mg
  • Price$225
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC6403
  • Product descriptionIcatibant Acetate
  • Packaging10mg
  • Price$360
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberHY-108896
  • Product descriptionIcatibant acetate 99.87%
  • Packaging10mg
  • Price$361
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-108896
  • Product descriptionIcatibant acetate 99.87%
  • Packaging5mg
  • Price$228
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0018T0 L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (salt) 2mg $99 2026-05-28 Buy
aablocks AA0018T0 L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (salt) 5mg $178 2026-05-28 Buy
aablocks AA0018T0 L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (salt) ≥98% 50mg $189 2026-05-28 Buy
aablocks AA0018T0 L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (salt) ≥98% 100mg $324 2026-05-28 Buy
aablocks AA0018T0 L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (salt) 1mg $72 2026-05-28 Buy
aablocks AA0018T0 L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (salt) ≥98% 250mg $551 2026-05-28 Buy
ACHEMBLOCK Z238474 Icatibant Acetate 98% 100MG $250 2026-05-27 Buy
ACHEMBLOCK Z238474 Icatibant Acetate 98% 25MG $125 2026-05-27 Buy
American Custom Chemicals Corporation API0010072 ICATIBANT ACETATE 95.00% 1MG $525 2021-12-16 Buy
American Custom Chemicals Corporation API0010072 ICATIBANT ACETATE 95.00% 5MG $775 2021-12-16 Buy
ApexBio Technology C6403 Icatibant Acetate 25mg $620 2026-05-06 Buy
ApexBio Technology C6403 Icatibant Acetate 1mg $90 2026-05-06 Buy
ApexBio Technology C6403 Icatibant Acetate 5mg $225 2026-05-06 Buy
ApexBio Technology C6403 Icatibant Acetate 10mg $360 2026-05-06 Buy
Arctom HY-108896 Icatibant acetate 99.87% 10mg $361 2026-05-26 Buy
Arctom HY-108896 Icatibant acetate 99.87% 5mg $228 2026-05-26 Buy

Properties

storage temp. :-20°C
solubility :DMSO:65.0(Max Conc. mg/mL);47.63(Max Conc. mM)
Ethanol:0.25(Max Conc. mg/mL);0.18(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);7.33(Max Conc. mM) form :A crystalline solid
color :White to off-white
InChIKey :HKMZRZUEADSZDQ-SUJPMXFINA-N

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Although it is a rare disease, HAE is an autosomal dominant disorder that can be potentially life-threatening when swelling manifests itself within the upper airways. Antagonism of the constitutively expressed B2 receptor, therefore, would not only be beneficial in the treatment of HAE but also find application in inflammatory, allergic, and hyperalgesic disorders.Designed to possess enhanced metabolic stability with the inclusion of five non-proteinogenic amino acids, icatibant is a competitive and selective B2 receptor antagonist (devoid of activity against the inducible B1 receptor) with a Ki of 2.2±0.7 nM, and it is the first downstream targeting agent to receive regulatory approval. It joins purified C1 esterase inhibitor, danazol (an attenuated androgen), and tranexamic acid (an antifibrinolytic agent) as acute and prophylactic treatments for HAE.

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