Lacosamide
|
- $49 - $2140
- Product name: Lacosamide
- CAS: 175481-36-4
- MF: C13H18N2O3
- MW: 250.29
- EINECS:605-756-0
- MDL Number:MFCD08272557
- Synonyms:LACOSAMIDE;(2R)-2-(Acetylamino)-3-methoxy-N-(phenylmethyl)propanamide;ADD 243037;Harkoseride;SPM 927;(2R)-N-benzyl-2-acetaMido-3-MethoxypropanaMide;LacosaMide (1.0Mg/ML in Acetonitrile);(R)-2-Acetamido-N-benzyl-3-methoxypropionamide
26 prices
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Brand
- Axon Medchem
- Biosynth
- Cayman Chemical
- DC Chemicals
- Sigma-Aldrich
Package
- 5mg
- 25mg
- 10mg
- 10mM*1mLinDMSO
- 50mg
- 100mg
- 250mg
- 1g
- 1mL
- 2g
- 5g
- 10g
- 25g
- 50g
- 5 mg
- 25 mg
- ManufacturerAxon Medchem
- Product numberAxon1444
- Product descriptionLacosamide 99%
- Packaging10mg
- Price$82.5
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1444
- Product descriptionLacosamide 99%
- Packaging50mg
- Price$220
- Updated2026-05-19
- Buy
- ManufacturerBiosynth
- Product numberFL24825
- Product descriptionLacosamide
- Packaging2g
- Price$267.52
- Updated2026-06-04
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- ManufacturerBiosynth
- Product numberBL164605
- Product descriptionLacosamide
- Packaging50mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberBL164605
- Product descriptionLacosamide
- Packaging10mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberBL164605
- Product descriptionLacosamide - Bio-X ?
- Packaging10mg
- Price$150
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFL24825
- Product descriptionLacosamide
- Packaging5g
- Price$579.65
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFL24825
- Product descriptionLacosamide
- Packaging10g
- Price$891.8
- Updated2026-06-04
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- ManufacturerBiosynth
- Product numberFL24825
- Product descriptionLacosamide
- Packaging25g
- Price$1427.25
- Updated2026-06-04
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- ManufacturerBiosynth
- Product numberFL24825
- Product descriptionLacosamide
- Packaging50g
- Price$2140
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number10012592
- Product descriptionLacosamide ≥98%
- Packaging25mg
- Price$152
- Updated2024-03-01
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- ManufacturerCayman Chemical
- Product number10012592
- Product descriptionLacosamide ≥98%
- Packaging25mg
- Price$168
- Updated2026-04-30
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- ManufacturerCayman Chemical
- Product number10012592
- Product descriptionLacosamide ≥98%
- Packaging50mg
- Price$306
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number10012592
- Product descriptionLacosamide ≥98%
- Packaging5mg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10012592
- Product descriptionLacosamide ≥98%
- Packaging5mg
- Price$54
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number10012592
- Product descriptionLacosamide ≥98%
- Packaging10mg
- Price$87
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Axon Medchem | Axon1444 | Lacosamide 99% | 10mg | $82.5 | 2026-05-19 | Buy |
| Axon Medchem | Axon1444 | Lacosamide 99% | 50mg | $220 | 2026-05-19 | Buy |
| Biosynth | FL24825 | Lacosamide | 2g | $267.52 | 2026-06-04 | Buy |
| Biosynth | BL164605 | Lacosamide | 50mg | $175 | 2021-12-16 | Buy |
| Biosynth | BL164605 | Lacosamide | 10mg | $68 | 2021-12-16 | Buy |
| Biosynth | BL164605 | Lacosamide - Bio-X ? | 10mg | $150 | 2026-06-04 | Buy |
| Biosynth | FL24825 | Lacosamide | 5g | $579.65 | 2026-06-04 | Buy |
| Biosynth | FL24825 | Lacosamide | 10g | $891.8 | 2026-06-04 | Buy |
| Biosynth | FL24825 | Lacosamide | 25g | $1427.25 | 2026-06-04 | Buy |
| Biosynth | FL24825 | Lacosamide | 50g | $2140 | 2026-06-04 | Buy |
| Cayman Chemical | 10012592 | Lacosamide ≥98% | 25mg | $152 | 2024-03-01 | Buy |
| Cayman Chemical | 10012592 | Lacosamide ≥98% | 25mg | $168 | 2026-04-30 | Buy |
| Cayman Chemical | 10012592 | Lacosamide ≥98% | 50mg | $306 | 2026-04-30 | Buy |
| Cayman Chemical | 10012592 | Lacosamide ≥98% | 5mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 10012592 | Lacosamide ≥98% | 5mg | $54 | 2026-04-30 | Buy |
| Cayman Chemical | 10012592 | Lacosamide ≥98% | 10mg | $87 | 2024-03-01 | Buy |
Properties
Melting point :141-143C
alpha :D23 +16.0° (c = 1 in CH3OH)
Boiling point :536.4±50.0 °C(Predicted)
Density :1.120±0.06 g/cm3(Predicted)
Flash point :2℃
storage temp. :Refrigerator
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 2 mg/ml
form :A crystalline solid
pka :14.19±0.46(Predicted)
color :white to beige
optical activity :[α]/D 13 to 18° (C=0.5g/100mL, MeOH)
InChI :InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1
InChIKey :VPPJLAIAVCUEMN-GFCCVEGCSA-N
SMILES :C(NCC1=CC=CC=C1)(=O)[C@H](NC(C)=O)COC
CAS DataBase Reference :175481-36-4
alpha :D23 +16.0° (c = 1 in CH3OH)
Boiling point :536.4±50.0 °C(Predicted)
Density :1.120±0.06 g/cm3(Predicted)
Flash point :2℃
storage temp. :Refrigerator
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 2 mg/ml
form :A crystalline solid
pka :14.19±0.46(Predicted)
color :white to beige
optical activity :[α]/D 13 to 18° (C=0.5g/100mL, MeOH)
InChI :InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1
InChIKey :VPPJLAIAVCUEMN-GFCCVEGCSA-N
SMILES :C(NCC1=CC=CC=C1)(=O)[C@H](NC(C)=O)COC
CAS DataBase Reference :175481-36-4
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Lacosamide (LCM), (SPM 927, (R)-2-acetamido-N-benzyl-3-methoxypropionamide, previously referred to as harkoseride or ADD 234037) is a member of a series of functionalized amino acids that were specifically synthesized as anticonvulsant or antiepileptic drug. It reduces the spread of seizure activity in the brain. Lacosamide appears to have a dual mode of action: selective enhancement of sodium channel inactivation and modulation of collapsin response mediator protein-2. Compared to novel antiepileptic drugs, lacosamide has broader and higher efficacy, better tolerability, and improved pharmacokinetic properties. Lacosamide is in phase III clinical development for adjunctive treatment of patients with uncontrolled partial-onset seizures, and for monotherapy of patients with painful diabetic neuropathy. It is absorbed rapidly and completely after oral administration. Lacosamide has an elimination half-life of approximately 13 hours and a low potential for drug interactions. Additionally, lacosamide exhibits linear, dose-proportional pharmacokinetics with low intra- and interpatient variability.Related product price
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